DE602004014629D1 - Chinolinverbindungen und deren verwendungen - Google Patents
Chinolinverbindungen und deren verwendungenInfo
- Publication number
- DE602004014629D1 DE602004014629D1 DE602004014629T DE602004014629T DE602004014629D1 DE 602004014629 D1 DE602004014629 D1 DE 602004014629D1 DE 602004014629 T DE602004014629 T DE 602004014629T DE 602004014629 T DE602004014629 T DE 602004014629T DE 602004014629 D1 DE602004014629 D1 DE 602004014629D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- chinoline
- release
- methods
- receptor signaling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50260503P | 2003-09-12 | 2003-09-12 | |
| PCT/US2004/028411 WO2005033103A1 (en) | 2003-09-12 | 2004-09-01 | Quinoline compounds and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004014629D1 true DE602004014629D1 (de) | 2008-08-07 |
Family
ID=34421502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004014629T Expired - Fee Related DE602004014629D1 (de) | 2003-09-12 | 2004-09-01 | Chinolinverbindungen und deren verwendungen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8008501B2 (de) |
| EP (1) | EP1675850B1 (de) |
| AT (1) | ATE399165T1 (de) |
| DE (1) | DE602004014629D1 (de) |
| ES (1) | ES2308251T3 (de) |
| WO (1) | WO2005033103A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1984894A (zh) * | 2004-05-14 | 2007-06-20 | Irm责任有限公司 | 作为ppar调节剂的化合物和组合物 |
| WO2012154518A1 (en) | 2011-05-10 | 2012-11-15 | Merck Sharp & Dohme Corp. | Bipyridylaminopyridines as syk inhibitors |
| CA2834062A1 (en) | 2011-05-10 | 2012-11-15 | Merck Sharp & Dohme Corp. | Pyridyl aminopyridines as syk inhibitors |
| BR112013028900A2 (pt) | 2011-05-10 | 2017-01-03 | Merck Sharp & Dohe Corp | Composto, composição farmacêutica, e, método para o tratamento ou a prevenção de doenças |
| WO2013052394A1 (en) | 2011-10-05 | 2013-04-11 | Merck Sharp & Dohme Corp. | 2-pyridyl carboxamide-containing spleen tyrosine kinase (syk) inhibitors |
| US9006444B2 (en) | 2011-10-05 | 2015-04-14 | Merck Sharp & Dohme Corp. | Phenyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors |
| EP2763975B1 (de) | 2011-10-05 | 2016-04-06 | Merck Sharp & Dohme Corp. | 3-pyridyl-carboxamidhaltige milztyrosinkinase-(syk)-hemmer |
| EP2863914B1 (de) | 2012-06-20 | 2018-10-03 | Merck Sharp & Dohme Corp. | Pyrazolylderivate als syk-hemmer |
| US9487504B2 (en) | 2012-06-20 | 2016-11-08 | Merck Sharp & Dohme Corp. | Imidazolyl analogs as syk inhibitors |
| US9416111B2 (en) | 2012-06-22 | 2016-08-16 | Merck Sharp & Dohme Corp. | Substituted diazine and triazine spleen tyrosine kinease (Syk) inhibitors |
| EP2863916B1 (de) | 2012-06-22 | 2018-07-18 | Merck Sharp & Dohme Corp. | Substituierte pyridin-milz-tyrosinkinaseinhibitoren |
| WO2014031438A2 (en) | 2012-08-20 | 2014-02-27 | Merck Sharp & Dohme Corp. | SUBSTITUTED PHENYL SPLEEN TYROSINE KINASE (Syk) INHIBITORS |
| EP2900665B1 (de) | 2012-09-28 | 2018-01-03 | Merck Sharp & Dohme Corp. | Triazolylderivate als syk-hemmer |
| US9624210B2 (en) | 2012-12-12 | 2017-04-18 | Merck Sharp & Dohme Corp. | Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors |
| EP2934525B1 (de) | 2012-12-21 | 2019-05-08 | Merck Sharp & Dohme Corp. | Thiazolsubstituierte aminopyridine als milztyrosinkinasehemmer |
| EP2988749B1 (de) | 2013-04-26 | 2019-08-14 | Merck Sharp & Dohme Corp. | Thiazolsubstituierte aminopyridine als milztyrosinkinasehemmer |
| US9745295B2 (en) | 2013-04-26 | 2017-08-29 | Merck Sharp & Dohme Corp. | Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors |
| WO2015095445A1 (en) | 2013-12-20 | 2015-06-25 | Merck Sharp & Dohme Corp. | Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors |
| WO2015095444A1 (en) | 2013-12-20 | 2015-06-25 | Merck Sharp & Dohme Corp. | Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors |
| EP3082807B1 (de) | 2013-12-20 | 2018-07-04 | Merck Sharp & Dohme Corp. | Thiazolsubstituierte aminoheteroaryle als milztyrosinkinasehemmer |
| US9775839B2 (en) | 2014-03-13 | 2017-10-03 | Merck Sharp & Dohme Corp. | 2-pyrazine carboxamides as spleen tyrosine kinase inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES448386A1 (es) * | 1975-06-05 | 1978-04-16 | Hoechst Ag | Procedimiento para la preparacion de anilidas de acido 5-me-til-isoxazol-4-carboxilico. |
| DE3225169A1 (de) | 1982-07-06 | 1984-01-12 | Basf Ag, 6700 Ludwigshafen | Chinolinderivate, verfahren zu ihrer herstellung, diese enthaltende mikrobizide und ihre verwendung zur bekaempfung von pilzen |
| DE3621540A1 (de) | 1986-06-27 | 1988-01-07 | Basf Ag | Chinolinderivate, verfahren zu ihrer herstellung, diese enthaltende mikrobizide und ihre verwendung zur bekaempfung von bakterien und pilzen |
| WO1994024095A1 (en) | 1993-04-16 | 1994-10-27 | Abbott Laboratories | Immunosuppressive agents |
| JP4245682B2 (ja) * | 1997-12-25 | 2009-03-25 | 協和発酵キリン株式会社 | キノリン誘導体、イソキノリン誘導体、およびシンノリン誘導体、並びに抗炎症剤および抗アレルギー剤 |
-
2004
- 2004-09-01 DE DE602004014629T patent/DE602004014629D1/de not_active Expired - Fee Related
- 2004-09-01 WO PCT/US2004/028411 patent/WO2005033103A1/en active Search and Examination
- 2004-09-01 EP EP04782827A patent/EP1675850B1/de not_active Not-in-force
- 2004-09-01 ES ES04782827T patent/ES2308251T3/es active Active
- 2004-09-01 US US10/931,481 patent/US8008501B2/en active Active
- 2004-09-01 AT AT04782827T patent/ATE399165T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1675850A1 (de) | 2006-07-05 |
| ES2308251T3 (es) | 2008-12-01 |
| US8008501B2 (en) | 2011-08-30 |
| EP1675850B1 (de) | 2008-06-25 |
| US20050113412A1 (en) | 2005-05-26 |
| ATE399165T1 (de) | 2008-07-15 |
| WO2005033103A1 (en) | 2005-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |