DE602004010658D1 - Automatisches makromolekülprobenvorbereitungssystem - Google Patents
Automatisches makromolekülprobenvorbereitungssystemInfo
- Publication number
- DE602004010658D1 DE602004010658D1 DE602004010658T DE602004010658T DE602004010658D1 DE 602004010658 D1 DE602004010658 D1 DE 602004010658D1 DE 602004010658 T DE602004010658 T DE 602004010658T DE 602004010658 T DE602004010658 T DE 602004010658T DE 602004010658 D1 DE602004010658 D1 DE 602004010658D1
- Authority
- DE
- Germany
- Prior art keywords
- macromolecule
- mixture
- liquid mixture
- filter
- macromole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
- G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
- B01D61/146—Ultrafiltration comprising multiple ultrafiltration steps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/16—Feed pretreatment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/04—Specific process operations in the feed stream; Feed pretreatment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/20—Devices for withdrawing samples in the liquid or fluent state for flowing or falling materials
- G01N1/2035—Devices for withdrawing samples in the liquid or fluent state for flowing or falling materials by deviating part of a fluid stream, e.g. by drawing-off or tapping
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Electrochemistry (AREA)
- Sampling And Sample Adjustment (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/601,277 US7601545B2 (en) | 2003-06-20 | 2003-06-20 | Automated macromolecule sample preparation system |
PCT/US2004/019499 WO2004113875A1 (en) | 2003-06-20 | 2004-06-18 | Automated macromolecule sample preparation system |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004010658D1 true DE602004010658D1 (de) | 2008-01-24 |
Family
ID=33517939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004010658T Active DE602004010658D1 (de) | 2003-06-20 | 2004-06-18 | Automatisches makromolekülprobenvorbereitungssystem |
Country Status (5)
Country | Link |
---|---|
US (2) | US7601545B2 (de) |
EP (1) | EP1636563B1 (de) |
AT (1) | ATE381006T1 (de) |
DE (1) | DE602004010658D1 (de) |
WO (1) | WO2004113875A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110059462A1 (en) * | 2006-02-21 | 2011-03-10 | University Of South Florida | Automated particulate concentration system |
US20080308494A1 (en) * | 2007-05-30 | 2008-12-18 | Groton Biosystems, Llc | Fluid sampling interface apparatus |
US7986399B2 (en) * | 2007-10-23 | 2011-07-26 | Los Alamos National Security, Llc | Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy |
WO2009143555A1 (en) * | 2008-05-27 | 2009-12-03 | Ecowise Australia Pty Ltd | Concentration filtering and analysis of fluids |
US20100043883A1 (en) * | 2008-06-25 | 2010-02-25 | Groton Biosystems, Llc | System and method for automated sterile sampling of fluid from a vessel |
US20100047122A1 (en) * | 2008-06-25 | 2010-02-25 | Groton Biosystems, Llc | System and method for automated sterile sampling of fluid from a vessel |
EP2435154B1 (de) * | 2009-05-29 | 2019-07-31 | Waters Technologies Corporation | Chromatographievorrichtung und -verfahren unter verwendung mehrerer mikrofluidischer substrate |
WO2011038008A2 (en) | 2009-09-23 | 2011-03-31 | Groton Biosystems, Llc | Method and apparatus for sterile sampling for gmp reactor applications |
US9499782B2 (en) | 2011-05-06 | 2016-11-22 | Bend Research, Inc. | Automatic aseptic sampling valve for sampling from enclosed containers |
EP2771449A1 (de) | 2011-10-24 | 2014-09-03 | Bend Research, Inc. | Systeme und verfahren zur herstellung von bioprodukten |
US9389151B2 (en) * | 2012-11-05 | 2016-07-12 | Bend Research, Inc. | Fixed volume aseptic sampling valve for sampling from enclosed containers |
EP2950076B1 (de) * | 2014-05-26 | 2017-06-28 | CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement | Tragbares System zur automatischen Vorbereitung flüssiger und/oder fester Proben |
US10465157B2 (en) | 2014-08-19 | 2019-11-05 | General Electric Company | Systems and methods for aseptic sampling |
US10190950B2 (en) | 2014-10-31 | 2019-01-29 | General Electric Company | Semi-automated sampling system for aseptic sampling |
WO2016168747A1 (en) * | 2015-04-16 | 2016-10-20 | Terumo Bct, Inc. | Automated protein production and cell lysing |
US9810708B2 (en) * | 2015-11-05 | 2017-11-07 | The United States Of America, As Represented By The Secretary Of Agriculture | Automated sampling system |
US11348429B2 (en) | 2016-06-08 | 2022-05-31 | Siemens Healthcare Diagnostics Inc. | Apparatus, systems, and methods providing remote access warning |
US10566926B2 (en) * | 2016-10-26 | 2020-02-18 | Craig Bradley Edward Wildman | Systems and methods for collecting solar energy using a parabolic trough solar collector |
US20210008572A1 (en) * | 2018-03-27 | 2021-01-14 | M-I L.L.C. | Centrifuge system |
EP4206324A1 (de) * | 2022-01-04 | 2023-07-05 | Phynexus, Inc. | Reinigung von makromolekülen |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4167117A (en) | 1978-07-10 | 1979-09-11 | Exxon Production Research Company | Apparatus and method for sampling flowing fluids and slurries |
US4830969A (en) * | 1981-08-31 | 1989-05-16 | The Research Foundation Of State University Of New York | Process for the rapid and simple isolation of nucleic acids |
US5147522A (en) | 1987-03-16 | 1992-09-15 | Helena Laboratories Corporation | Automatic electrophoresis apparatus and method |
US4785676A (en) | 1987-08-19 | 1988-11-22 | Deoca Henry M | Aseptic sample fitting |
CA1332293C (en) | 1988-09-01 | 1994-10-11 | Gunilla K. E. Seifert | Automatic aseptic sampling apparatus |
US5169511A (en) | 1988-11-29 | 1992-12-08 | Isco, Inc. | Capillary electrophoresis technique |
US6645758B1 (en) * | 1989-02-03 | 2003-11-11 | Johnson & Johnson Clinical Diagnostics, Inc. | Containment cuvette for PCR and method of use |
US4999307A (en) | 1989-02-13 | 1991-03-12 | Baxter International Inc. | Apparatus and method for periodic aseptic withdrawal of liquid samples from a sterile liquid source |
DK3991D0 (da) | 1991-01-10 | 1991-01-10 | Novo Nordisk As | Fremgangsmaade til fremstilling af et proteinhydrolysat |
US5075905A (en) | 1991-01-17 | 1991-12-31 | Talmadge Rutherford | Drain trap assembly |
US5332481A (en) | 1991-01-29 | 1994-07-26 | Beckman Instruments, Inc. | Capillary electrophoresis using replaceable gels |
DE4133538C2 (de) | 1991-10-10 | 1993-11-11 | Waldemar Dr Neumueller | Verfahren zur Gewinnung von lebensmittelfähigen Proteinen aus einer proteinhaltigen Substanz |
US5785869A (en) * | 1992-02-10 | 1998-07-28 | Baxter International Inc. | Method for creating a leukocyte rich sample from a mixed population of blood cells |
US5296197A (en) | 1992-07-09 | 1994-03-22 | Nl Technologies, Limited | Automated sample extractor or feeder/inoculator for bioreactors and similar equipment |
US5429728A (en) | 1992-08-31 | 1995-07-04 | Hewlett-Packard Company | Electroosmotic flow control using back pressure in capillary electrophoresis |
US5395588A (en) | 1992-12-14 | 1995-03-07 | Becton Dickinson And Company | Control of flow cytometer having vacuum fluidics |
US5482608A (en) | 1993-01-19 | 1996-01-09 | Hewlett Packard Company | Capillary electrophoresis flow control system |
US5348633A (en) | 1993-01-22 | 1994-09-20 | Northeastern University | Method for quantitating trace amounts of an analyte in a sample by affinity capillary electrophoresis |
EP0620432B1 (de) | 1993-04-15 | 2004-08-25 | Zeptosens AG | Verfahren zur Steuerung der Probeneinführung bei Mikrosäulentrennungstechniken und Probenentnahmevorrichtungen |
US5372695A (en) | 1993-05-07 | 1994-12-13 | Applied Biosystems, Inc. | Application specific capillary electrophoresis |
US5460054A (en) | 1993-09-28 | 1995-10-24 | Tran; Sa C. | Apparatus for choke-free sampling of fluids and slurries |
GB9509905D0 (en) | 1995-05-11 | 1995-07-12 | Watson Arthur H | Fast sample device for capillary isoelectric focusing |
US5856174A (en) * | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
US5771917A (en) | 1995-09-25 | 1998-06-30 | Tri-Clover, Inc. | Sanitary aseptic drain system |
FR2740222B1 (fr) | 1995-10-23 | 1997-11-14 | Bio Merieux | Ensemble de traitement d'un echantillon en milieu liquide, notamment d'un materiel biologique |
SE9604441D0 (sv) | 1996-12-02 | 1996-12-02 | Vincenzo Vassarotti | Method, device and apparatus for concentrating and/or purifying macromolecules in a solution |
US5833826A (en) | 1996-12-13 | 1998-11-10 | The Perkin-Elmer Corporation | Method and apparatus for reducing the distortion of a sample zone eluting from a capillary electrophoresis capillary |
US5755155A (en) | 1997-02-28 | 1998-05-26 | Tetra Laval Holdings & Finance S.A. | Aseptic process interface group |
FI103438B1 (fi) | 1997-10-01 | 1999-06-30 | Valtion Teknillinen | Kapillaarielektroforeesilaite |
US5948998A (en) | 1998-02-09 | 1999-09-07 | Alberta Research Council | Sampling device for taking sterile samples |
US6537432B1 (en) | 1998-02-24 | 2003-03-25 | Target Discovery, Inc. | Protein separation via multidimensional electrophoresis |
US5971358A (en) | 1998-06-11 | 1999-10-26 | Penn Troy Machine Co., Inc. | Gate assembly for a double disk gate valve |
US6787111B2 (en) | 1998-07-02 | 2004-09-07 | Amersham Biosciences (Sv) Corp. | Apparatus and method for filling and cleaning channels and inlet ports in microchips used for biological analysis |
CA2374423C (en) * | 1999-05-28 | 2013-04-09 | Cepheid | Apparatus and method for analyzing a liquid sample |
US6418799B1 (en) | 1999-07-20 | 2002-07-16 | Csi Technology, Inc. | Sampling apparatus |
US6491872B1 (en) | 1999-09-17 | 2002-12-10 | The United States Of America As Represented By The Secretary Of The Army | Method and system for detecting and recording submicron sized particles |
FI116099B (fi) | 1999-12-08 | 2005-09-15 | Valtion Teknillinen | Menetelmä prosessista saadun näytteen analysoimiseksi on-line kapillaarielektroforeesilaitteiston avulla |
US6692702B1 (en) * | 2000-07-07 | 2004-02-17 | Coulter International Corp. | Apparatus for biological sample preparation and analysis |
WO2002093133A2 (en) | 2001-05-16 | 2002-11-21 | Akzo Nobel N.V. | Sampling of flammable liquefied gas |
US7060171B1 (en) | 2001-07-31 | 2006-06-13 | Caliper Life Sciences, Inc. | Methods and systems for reducing background signal in assays |
US6637257B2 (en) * | 2002-01-02 | 2003-10-28 | Integrated Sensing Systems | Micromachined fluid analysis device and method |
US7482169B2 (en) * | 2002-07-15 | 2009-01-27 | Phynexus, Inc. | Low dead volume extraction column device |
US7341652B2 (en) * | 2003-06-20 | 2008-03-11 | Groton Biosytems, Llc | Stationary capillary electrophoresis system |
US7169599B2 (en) | 2003-06-20 | 2007-01-30 | Groton Biosystems, Llc | Fluid interface for bioprocessor systems |
US20040260414A1 (en) * | 2003-06-20 | 2004-12-23 | Groton Biosystems, Llc | Method and apparatus for operating an automated biomolecular preparation system |
-
2003
- 2003-06-20 US US10/601,277 patent/US7601545B2/en not_active Expired - Fee Related
-
2004
- 2004-06-18 EP EP04755586A patent/EP1636563B1/de not_active Not-in-force
- 2004-06-18 WO PCT/US2004/019499 patent/WO2004113875A1/en active IP Right Grant
- 2004-06-18 AT AT04755586T patent/ATE381006T1/de not_active IP Right Cessation
- 2004-06-18 DE DE602004010658T patent/DE602004010658D1/de active Active
-
2009
- 2009-10-05 US US12/573,438 patent/US20100021880A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE381006T1 (de) | 2007-12-15 |
WO2004113875A1 (en) | 2004-12-29 |
US7601545B2 (en) | 2009-10-13 |
US20040259266A1 (en) | 2004-12-23 |
EP1636563A1 (de) | 2006-03-22 |
US20100021880A1 (en) | 2010-01-28 |
EP1636563B1 (de) | 2007-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |