DE60141045D1 - Auf rtvp basierende zusammensetzungen und verfahren zur behandlung von prostata-krebs - Google Patents
Auf rtvp basierende zusammensetzungen und verfahren zur behandlung von prostata-krebsInfo
- Publication number
- DE60141045D1 DE60141045D1 DE60141045T DE60141045T DE60141045D1 DE 60141045 D1 DE60141045 D1 DE 60141045D1 DE 60141045 T DE60141045 T DE 60141045T DE 60141045 T DE60141045 T DE 60141045T DE 60141045 D1 DE60141045 D1 DE 60141045D1
- Authority
- DE
- Germany
- Prior art keywords
- rtvp
- mrtvp
- prostate cancer
- mouse
- activities
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010060862 Prostate cancer Diseases 0.000 title abstract 4
- 208000000236 Prostatic Neoplasms Diseases 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000006907 apoptotic process Effects 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 230000001394 metastastic effect Effects 0.000 abstract 2
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 102100021569 Apoptosis regulator Bcl-2 Human genes 0.000 abstract 1
- 108090000397 Caspase 3 Proteins 0.000 abstract 1
- 102100029855 Caspase-3 Human genes 0.000 abstract 1
- 102100026548 Caspase-8 Human genes 0.000 abstract 1
- 108090000538 Caspase-8 Proteins 0.000 abstract 1
- 102100026550 Caspase-9 Human genes 0.000 abstract 1
- 108090000566 Caspase-9 Proteins 0.000 abstract 1
- 102100030497 Cytochrome c Human genes 0.000 abstract 1
- 108010075031 Cytochromes c Proteins 0.000 abstract 1
- 206010053759 Growth retardation Diseases 0.000 abstract 1
- 101000971171 Homo sapiens Apoptosis regulator Bcl-2 Proteins 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 238000009825 accumulation Methods 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 230000001772 anti-angiogenic effect Effects 0.000 abstract 1
- 230000002001 anti-metastasis Effects 0.000 abstract 1
- 230000005975 antitumor immune response Effects 0.000 abstract 1
- 102000055102 bcl-2-Associated X Human genes 0.000 abstract 1
- 108700000711 bcl-X Proteins 0.000 abstract 1
- 102000055104 bcl-X Human genes 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000012761 co-transfection Methods 0.000 abstract 1
- 230000001086 cytosolic effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000002919 epithelial cell Anatomy 0.000 abstract 1
- 230000014509 gene expression Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 238000010172 mouse model Methods 0.000 abstract 1
- 230000009826 neoplastic cell growth Effects 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000002018 overexpression Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001629 suppression Effects 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20998900P | 2000-06-08 | 2000-06-08 | |
| PCT/US2001/018487 WO2002006344A2 (en) | 2000-06-08 | 2001-06-08 | Rtvp based compositions and methods for the treatment of prostate cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60141045D1 true DE60141045D1 (de) | 2010-02-25 |
Family
ID=22781163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60141045T Expired - Lifetime DE60141045D1 (de) | 2000-06-08 | 2001-06-08 | Auf rtvp basierende zusammensetzungen und verfahren zur behandlung von prostata-krebs |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20020052025A1 (de) |
| EP (1) | EP1355944B1 (de) |
| AT (1) | ATE454400T1 (de) |
| AU (1) | AU2001266767A1 (de) |
| CA (1) | CA2412183C (de) |
| DE (1) | DE60141045D1 (de) |
| WO (1) | WO2002006344A2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020052025A1 (en) * | 2000-06-08 | 2002-05-02 | Thompson Timothy C. | RTVP based compositions and methods for the treatment of prostate cancer |
| US20050187153A1 (en) * | 2001-06-08 | 2005-08-25 | Baylor College Of Medicine | RTVP based compositions and methods for the treatment of prostate cancer, autoimmunity and infectious disease |
| WO2005002413A2 (en) * | 2003-07-01 | 2005-01-13 | Bar Ilan University | Methods and reagents for diagnosing gliomas and treating gliomas |
| US7824685B2 (en) * | 2004-01-26 | 2010-11-02 | Baylor College Of Medicine | RTVP based compositions and methods for the treatment of prostate cancer |
| WO2007099529A1 (en) * | 2006-02-28 | 2007-09-07 | Sandisk Il Ltd | Bookmarked synchronization of files |
| US8367052B2 (en) | 2007-03-26 | 2013-02-05 | General Regeneratives Holdings Inc. | Methods for promoting protection and regeneration of bone marrow using CXCL9 and anti-CXCL9 antibodies |
| US20130156777A1 (en) * | 2011-09-12 | 2013-06-20 | Raymond A. Koski | Glipr1 inhibitors and therapeutic uses thereof |
| US10256831B2 (en) | 2016-09-21 | 2019-04-09 | Analog Devices Global | Method and apparatus to reduce effect of dielectric absorption in SAR ADC |
| WO2020033536A1 (en) * | 2018-08-07 | 2020-02-13 | Glipper Oncology Research, Inc. | Compositions of glipr fusion proteins and methods for the treatment of prostate cancer |
| USD947732S1 (en) | 2020-08-04 | 2022-04-05 | Polaris Industries Inc. | Hood for an off-road vehicle |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5789200A (en) * | 1996-10-31 | 1998-08-04 | Smithkline Beecham Corporation | Human ETS family member, ELF3 |
| US5856130A (en) * | 1996-12-26 | 1999-01-05 | Incyte Pharmaceuticals, Inc. | Human pathogenesis-related protein |
| AU3316600A (en) | 1999-02-22 | 2000-09-21 | Torben F. Orntoft | Gene expression in bladder tumors |
| US20020052308A1 (en) | 1999-03-12 | 2002-05-02 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| US20030219743A1 (en) | 2000-05-18 | 2003-11-27 | Tang Y. Tom | Novel nucleic acids and polypeptides |
| US20020052025A1 (en) | 2000-06-08 | 2002-05-02 | Thompson Timothy C. | RTVP based compositions and methods for the treatment of prostate cancer |
| IT1318937B1 (it) * | 2000-09-27 | 2003-09-19 | Getters Spa | Metodo per la produzione di dispositivi getter porosi con ridottaperdita di particelle e dispositivi cosi' prodotti |
| US20030119009A1 (en) | 2001-02-23 | 2003-06-26 | Stuart Susan G. | Genes regulated by MYCN activation |
| US6783969B1 (en) | 2001-03-05 | 2004-08-31 | Nuvelo, Inc. | Cathepsin V-like polypeptides |
| WO2003029468A1 (en) | 2001-10-02 | 2003-04-10 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
| JP2003135075A (ja) | 2001-11-05 | 2003-05-13 | Research Association For Biotechnology | 新規な全長ｃＤＮＡ |
| US20040029151A1 (en) | 2002-04-09 | 2004-02-12 | Affymetrix, Inc. | Molecular genetic profiling of gleason grades 3 and 4/5 prostate cancer |
| US7601806B2 (en) | 2003-06-09 | 2009-10-13 | Baylor College Of Medicine | RTVP-GliPR-like compositions and methods for the detection, treatment and prevention of prostate cancer |
| WO2005002413A2 (en) | 2003-07-01 | 2005-01-13 | Bar Ilan University | Methods and reagents for diagnosing gliomas and treating gliomas |
-
2001
- 2001-06-08 US US09/876,225 patent/US20020052025A1/en not_active Abandoned
- 2001-06-08 DE DE60141045T patent/DE60141045D1/de not_active Expired - Lifetime
- 2001-06-08 AT AT01944345T patent/ATE454400T1/de not_active IP Right Cessation
- 2001-06-08 EP EP01944345A patent/EP1355944B1/de not_active Expired - Lifetime
- 2001-06-08 WO PCT/US2001/018487 patent/WO2002006344A2/en active Search and Examination
- 2001-06-08 AU AU2001266767A patent/AU2001266767A1/en not_active Abandoned
- 2001-06-08 CA CA2412183A patent/CA2412183C/en not_active Expired - Lifetime
-
2003
- 2003-04-17 US US10/417,727 patent/US7645452B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1355944B1 (de) | 2010-01-06 |
| US7645452B2 (en) | 2010-01-12 |
| AU2001266767A1 (en) | 2002-01-30 |
| WO2002006344A2 (en) | 2002-01-24 |
| WO2002006344A3 (en) | 2003-08-21 |
| CA2412183A1 (en) | 2002-01-24 |
| ATE454400T1 (de) | 2010-01-15 |
| CA2412183C (en) | 2010-08-03 |
| US20040009508A1 (en) | 2004-01-15 |
| EP1355944A2 (de) | 2003-10-29 |
| US20020052025A1 (en) | 2002-05-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Jang et al. | Breast cancer cell–derived soluble CD44 promotes tumor progression by triggering macrophage IL1β production | |
| Chang et al. | Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model | |
| Sharma et al. | Immunohistochemical evaluation of mast cells and angiogenesis in oral squamous cell carcinoma | |
| MX9804009A (es) | Inhibicion de crecimiento tumoral por oligonucleotidos de antisentido para il-8 y receptor de il-8. | |
| DE60141045D1 (de) | Auf rtvp basierende zusammensetzungen und verfahren zur behandlung von prostata-krebs | |
| Laakkonen et al. | Peptide targeting of tumor lymph vessels | |
| CY1107074T1 (el) | Συνθεση εναντιομερων 4-αμινο-θαλιδομιδης | |
| CA2311409A1 (en) | Treatment with anti-erbb2 antibodies | |
| MXPA02011379A (es) | Ensayo de deteccion de genes para mejorar la probabilidad de una respuesta efectiva a terapia de cancer con el antagonista erbb. | |
| WO2003027094A3 (en) | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | |
| WO2004048525A3 (en) | Therapy of non-malignant diseases or disorders with anti-erbb2 antibodies | |
| DK1187918T3 (da) | TEK-antagonister | |
| RS105304A (en) | Methods of treating angiogenesis,tumor growth,and metastasis | |
| RU2015149285A (ru) | Схемы дозирования иммуноконъюгата anti-folr1 | |
| DE69921130D1 (de) | Verfahren und stoffe zur behandlung des prostatakarzinomes | |
| Yin et al. | RETRACTED: Resibufogenin suppresses growth and metastasis through inducing caspase‐1‐dependent pyroptosis via ROS‐mediated NF‐κB suppression in non‐small cell lung cancer | |
| DE60328772D1 (de) | Epothilonderivat zur behandlung von hepatoma und anderen krebserkrankungen | |
| DE60136212D1 (de) | Diagnose und behandlung von tumor-suppressor assoziierten krankheiten | |
| Reichrath et al. | Notch-signaling and nonmelanoma skin cancer: an ancient friend, revisited | |
| SG148190A1 (en) | Angiogenesis inhibiting molecules and their use in the treatment and diagnosis of cancer | |
| ATE462441T1 (de) | Saposin c und rezeptoren als ziele für die behandlung von gutartigen und bösartigen erkrankungen | |
| Jindal et al. | Heat shock proteins in pathology: a review | |
| JP2018509469A5 (de) | ||
| ATE293985T1 (de) | Verwendung von extrakten aus cimicifuga-arten als organselektives arzneimittel zur behandlung von sexualhormonabhängigen erkrankungen des urogenitaltraktes | |
| Zheng et al. | IGHG1 functions as an oncogene in tongue squamous cell carcinoma via JAK1/STAT5 signaling. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |