DE60136277D1 - METHOD FOR DETECTING CANCER - Google Patents

METHOD FOR DETECTING CANCER

Info

Publication number
DE60136277D1
DE60136277D1 DE60136277T DE60136277T DE60136277D1 DE 60136277 D1 DE60136277 D1 DE 60136277D1 DE 60136277 T DE60136277 T DE 60136277T DE 60136277 T DE60136277 T DE 60136277T DE 60136277 D1 DE60136277 D1 DE 60136277D1
Authority
DE
Germany
Prior art keywords
cancer
gene
classification
expression
altered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60136277T
Other languages
German (de)
Inventor
Yasuhiro Tsubosa
Kazuhiko Aoyagi
Hiroki Sasaki
Masaaki Terada
Junichi Mineno
Kiyozo Asada
Ikunoshin Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takara Bio Inc
Original Assignee
Takara Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Bio Inc filed Critical Takara Bio Inc
Application granted granted Critical
Publication of DE60136277D1 publication Critical patent/DE60136277D1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

To provide a method for selecting a marker gene useful for cancer classification; a method for classifying cancer using the gene; a method for detecting cancer; a kit usable for the classification method or detection method; and a DNA array carrying the gene. According to the present invention, there can be obtained a gene, wherein expression of the above gene is altered independently from genes each of which expression is altered specifically during cell proliferation and expression level of the above gene is specifically altered depending on every type of cancer samples to be tested, whereby the classification or detection of cancer can be carried out conveniently and quickly without giving surgical treatment. Therefore, the present invention is useful for the diagnosis, the treatment, and the like of cancer.
DE60136277T 2000-07-19 2001-07-18 METHOD FOR DETECTING CANCER Expired - Fee Related DE60136277D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000219807 2000-07-19
PCT/JP2001/006201 WO2002006484A1 (en) 2000-07-19 2001-07-18 Method of detecting cancer

Publications (1)

Publication Number Publication Date
DE60136277D1 true DE60136277D1 (en) 2008-12-04

Family

ID=18714521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60136277T Expired - Fee Related DE60136277D1 (en) 2000-07-19 2001-07-18 METHOD FOR DETECTING CANCER

Country Status (7)

Country Link
US (2) US20050048480A1 (en)
EP (1) EP1304377B1 (en)
AT (1) ATE412053T1 (en)
AU (1) AU2002222939A1 (en)
DE (1) DE60136277D1 (en)
TW (1) TWI316959B (en)
WO (1) WO2002006484A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10250530A1 (en) * 2002-10-29 2004-05-13 Mediagnost Gesellschaft für Forschung und Herstellung von Diagnostika mbH Method for the detection of hepatocellular carcinoma and test system
US20090005268A1 (en) * 2005-07-18 2009-01-01 Epigenomics Ag Compositions and Methods for Cancer Diagnostics Comprising Pan-Cancer Markers
EP1934377B1 (en) * 2005-09-02 2012-03-07 The University of Toledo Methods for identifying biomarkers useful in diagnosis of biological states
US20070207467A1 (en) * 2006-03-01 2007-09-06 Ming Xu Detection of lymph node metastasis from gastric carcinoma
GB2436564A (en) * 2006-03-31 2007-10-03 Plant Bioscience Ltd Prediction of heterosis and other traits by transcriptome analysis
US20070281305A1 (en) * 2006-06-05 2007-12-06 Sean Wuxiong Cao Detection of lymph node metastasis from gastric carcinoma
EP2032989B2 (en) * 2006-06-30 2015-10-28 Merck Sharp & Dohme Corp. Igfbp2 biomarker
WO2009145924A2 (en) * 2008-05-31 2009-12-03 Indiana University Research & Technology Corporation Methods and materials for identifying patients at heightened risk for developing her2+ related brain tumors
WO2009154790A2 (en) * 2008-06-20 2009-12-23 University Of Massachusetts Novel metastasis suppresor genes and uses thereof
MA40913A (en) 2014-11-14 2017-09-20 Novartis Ag ANTIBODY-DRUG CONJUGATES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552277A (en) * 1994-07-19 1996-09-03 The Johns Hopkins University School Of Medicine Genetic diagnosis of prostate cancer
WO2001074405A1 (en) * 2000-03-31 2001-10-11 Gene Logic, Inc. Gene expression profiles in esophageal tissue

Also Published As

Publication number Publication date
EP1304377A4 (en) 2004-08-11
EP1304377A1 (en) 2003-04-23
EP1304377B1 (en) 2008-10-22
WO2002006484A1 (en) 2002-01-24
TWI316959B (en) 2009-11-11
ATE412053T1 (en) 2008-11-15
US20050048480A1 (en) 2005-03-03
AU2002222939A1 (en) 2002-01-30
US20090156420A1 (en) 2009-06-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee