DE60130782D1 - Atemwegspezifische, trypsin-ähnliche enzyme und verfahren zu deren anwendung - Google Patents

Atemwegspezifische, trypsin-ähnliche enzyme und verfahren zu deren anwendung

Info

Publication number
DE60130782D1
DE60130782D1 DE60130782T DE60130782T DE60130782D1 DE 60130782 D1 DE60130782 D1 DE 60130782D1 DE 60130782 T DE60130782 T DE 60130782T DE 60130782 T DE60130782 T DE 60130782T DE 60130782 D1 DE60130782 D1 DE 60130782D1
Authority
DE
Germany
Prior art keywords
airway
trypsin
methods
specific
similar enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60130782T
Other languages
English (en)
Other versions
DE60130782T2 (de
Inventor
Hiroshi Eguchi
Manabu Chokki
Satoshi Yamamura
Reiko Mita
Tsukio Masegi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of DE60130782D1 publication Critical patent/DE60130782D1/de
Application granted granted Critical
Publication of DE60130782T2 publication Critical patent/DE60130782T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6427—Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60130782T 2000-08-28 2001-08-28 Atemwegspezifische, trypsin-ähnliche enzyme und verfahren zu deren anwendung Expired - Lifetime DE60130782T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2000257104 2000-08-28
JP2000257104 2000-08-28
JP2001059753 2001-03-05
JP2001059753 2001-03-05
PCT/JP2001/007349 WO2002018562A1 (fr) 2000-08-28 2001-08-28 Enzymes de type trypsine propres aux voies respiratoires et leur procede d'utilisation

Publications (2)

Publication Number Publication Date
DE60130782D1 true DE60130782D1 (de) 2007-11-15
DE60130782T2 DE60130782T2 (de) 2008-07-03

Family

ID=26598571

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60130782T Expired - Lifetime DE60130782T2 (de) 2000-08-28 2001-08-28 Atemwegspezifische, trypsin-ähnliche enzyme und verfahren zu deren anwendung

Country Status (6)

Country Link
EP (1) EP1314779B1 (de)
AU (1) AU2001280198A1 (de)
DE (1) DE60130782T2 (de)
HK (1) HK1052371B (de)
TW (2) TWI317379B (de)
WO (1) WO2002018562A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
DE10258051A1 (de) * 2002-12-11 2004-07-22 Metagen Pharmaceuticals Gmbh Verwendung von an HAT bindenden Substanzen zur Diagnose und Behandlung des Plattenepithelkarzinoms der Lunge
GB2445920A (en) * 2007-01-25 2008-07-30 Mucokinetica Ltd Amidino compounds for treatment of respiratory disease
WO2011015380A1 (en) * 2009-08-05 2011-02-10 Celltrend Gmbh Method for prognosis of pulmonary arterial hypertension by detecting anti-par2-antibodies
WO2021142245A1 (en) * 2020-01-10 2021-07-15 Translate Bio, Inc. Compounds, pharmaceutical compositions and methods for modulating expression of muc5b in lung cells and tissues

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0699763B1 (de) * 1994-07-29 1998-09-30 Teijin Limited Trypsintyp-Enzyme, dafür kodierende Nukleinsäuresequenz und Verfahren zur Herstellung des Enzymes
WO1999031271A1 (en) * 1997-12-16 1999-06-24 Teijin Limited Analysis of predisposition based on human airway tripsin protease gene polymorphism
ID27813A (id) * 1998-01-28 2001-04-26 Corixa Corp Senyawa-senyawa untuk terapi dan diagnosa kanker paru-paru dan metoda untuk penggunaannya
WO2000060077A2 (en) * 1999-04-02 2000-10-12 Corixa Corporation Compounds for therapy and diagnosis of lung cancer and methods for their use
EP1152057A4 (de) * 1999-12-06 2004-05-12 Teijin Ltd Antikorper, die menschliches trypsin-ahnliches enzym aus dem atemweg binden und deren verwendung

Also Published As

Publication number Publication date
AU2001280198A1 (en) 2002-03-13
EP1314779A4 (de) 2005-02-16
HK1052371A1 (en) 2003-09-11
EP1314779A1 (de) 2003-05-28
TWI317379B (en) 2009-11-21
WO2002018562A1 (fr) 2002-03-07
TW200808969A (en) 2008-02-16
TWI317380B (en) 2009-11-21
DE60130782T2 (de) 2008-07-03
EP1314779B1 (de) 2007-10-03
HK1052371B (zh) 2007-12-28

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