DE60127821D1 - Verfahren zur Bestimmung der Reaktionen und der Metabolischen Aktivitat mit Fluoreszentem temperaturempfindlichem Material - Google Patents
Verfahren zur Bestimmung der Reaktionen und der Metabolischen Aktivitat mit Fluoreszentem temperaturempfindlichem MaterialInfo
- Publication number
- DE60127821D1 DE60127821D1 DE60127821T DE60127821T DE60127821D1 DE 60127821 D1 DE60127821 D1 DE 60127821D1 DE 60127821 T DE60127821 T DE 60127821T DE 60127821 T DE60127821 T DE 60127821T DE 60127821 D1 DE60127821 D1 DE 60127821D1
- Authority
- DE
- Germany
- Prior art keywords
- reactions
- determination
- sensitive material
- metabolic activity
- fluorescence temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5029—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell motility
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Clinical Laboratory Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plasma & Fusion (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01401376A EP1262764B1 (de) | 2001-05-25 | 2001-05-25 | Verfahren zur Bestimmung der Reaktionen und der Metabolischen Aktivitat mit Fluoreszentem temperaturempfindlichem Material |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60127821D1 true DE60127821D1 (de) | 2007-05-24 |
Family
ID=8182745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60127821T Expired - Lifetime DE60127821D1 (de) | 2001-05-25 | 2001-05-25 | Verfahren zur Bestimmung der Reaktionen und der Metabolischen Aktivitat mit Fluoreszentem temperaturempfindlichem Material |
Country Status (3)
Country | Link |
---|---|
US (1) | US20030012692A1 (de) |
EP (1) | EP1262764B1 (de) |
DE (1) | DE60127821D1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080319795A1 (en) * | 2002-11-21 | 2008-12-25 | Cdex, Inc. | System and methods for detection and identification of chemical substances |
US7027163B2 (en) * | 2003-01-24 | 2006-04-11 | General Dynamics Advanced Information Systems, Inc. | Grating sensor |
US8597597B2 (en) | 2003-06-26 | 2013-12-03 | Seng Enterprises Ltd. | Picoliter well holding device and method of making the same |
US9200245B2 (en) | 2003-06-26 | 2015-12-01 | Seng Enterprises Ltd. | Multiwell plate |
US7888110B2 (en) | 2003-06-26 | 2011-02-15 | Seng Enterprises Ltd. | Pico liter well holding device and method of making the same |
WO2007074449A2 (en) * | 2005-12-28 | 2007-07-05 | Seng Enterprises Ltd. | Substantially invisible three-dimensional structure for the study of cells |
DE602005023534D1 (de) | 2005-01-25 | 2010-10-21 | Seng Entpr Ltd | Mikrofluidische vorrichtung zur untersuchung zellen |
US20060223051A1 (en) * | 2005-04-05 | 2006-10-05 | Ye Fang | System and method for performing G protein coupled receptor (GPCR) cell assays using waveguide-grating sensors |
CN101500481B (zh) | 2005-04-05 | 2014-07-02 | 康宁股份有限公司 | 一种测定刺激事件对细胞产生的影响的方法 |
WO2007052245A1 (en) | 2005-11-03 | 2007-05-10 | Seng Enterprises Ltd. | Method and device for studying floating, living cells |
US20080113391A1 (en) | 2006-11-14 | 2008-05-15 | Ian Gibbons | Detection and quantification of analytes in bodily fluids |
WO2008130488A1 (en) * | 2007-04-19 | 2008-10-30 | Corning Incorporated | Live-cell signals of pathogen intrusion and methods thereof |
WO2009019619A1 (en) * | 2007-08-09 | 2009-02-12 | Koninklijke Philips Electronics N. V. | Microelectronic sensor device for optical examinations in a sample medium |
US20090309617A1 (en) * | 2007-08-24 | 2009-12-17 | Ye Fang | Biosensor antibody functional mapping |
US8703428B2 (en) | 2007-10-06 | 2014-04-22 | Corning Incorporated | Single-cell label-free assay |
US8426148B2 (en) | 2007-10-06 | 2013-04-23 | Corning Incorporated | Label-free methods using a resonant waveguide grating biosensor to determine GPCR signaling pathways |
US9975118B2 (en) | 2007-11-15 | 2018-05-22 | Seng Enterprises Ltd. | Device for the study of living cells |
US9145540B1 (en) | 2007-11-15 | 2015-09-29 | Seng Enterprises Ltd. | Device for the study of living cells |
US20090181409A1 (en) * | 2008-01-10 | 2009-07-16 | Ye Fang | Optical biosensor method for cell-cell interaction |
KR100948810B1 (ko) * | 2008-04-08 | 2010-03-24 | 전남대학교산학협력단 | 다채널 생물반응기 온라인 모니터링장치 |
US9393566B2 (en) * | 2008-06-23 | 2016-07-19 | Canon U.S. Life Sciences, Inc. | System and method for temperature referencing for melt curve data collection |
EP2504103A2 (de) * | 2009-11-23 | 2012-10-03 | 3M Innovative Properties Company | Mikrowellenarrayartikel und verfahren zu ihrer verwendung |
EP2524206A1 (de) * | 2010-01-13 | 2012-11-21 | Flowsion ApS | Mikrofluidisches system mit einer lichtemittierenden vorrichtung |
US20110207789A1 (en) * | 2010-02-19 | 2011-08-25 | Ye Fang | Methods related to casein kinase ii (ck2) inhibitors and the use of purinosome-disrupting ck2 inhibitors for anti-cancer therapy agents |
CN103018808B (zh) * | 2011-09-23 | 2015-05-13 | 中国科学院微电子研究所 | 光子筛及其制作方法 |
CN103091749A (zh) * | 2011-10-31 | 2013-05-08 | 中国科学院微电子研究所 | 一种高透过率光子筛 |
EP2604342B1 (de) * | 2011-12-12 | 2014-06-25 | ibidi GmbH | Probenkammer mit Trennplatte |
US9423234B2 (en) | 2012-11-05 | 2016-08-23 | The Regents Of The University Of California | Mechanical phenotyping of single cells: high throughput quantitative detection and sorting |
EP2859948A1 (de) * | 2013-10-09 | 2015-04-15 | Yantai AusBio Laboratories Co., Ltd. | Verfahren zur Bestimmung des Ergebnisses einer Agglutinationsreaktion und Mikroplatte zur Bestimmung der Produkte von Agglutinationsreaktionen |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4819658A (en) * | 1982-02-11 | 1989-04-11 | American Telephone And Telegraph Company, At&T Bell Laboratories | Method and apparatus for measuring the temperature profile of a surface |
US4455741A (en) * | 1982-02-11 | 1984-06-26 | At&T Bell Laboratories | Fabrication of solid state electronic devices using fluorescent imaging of surface temperature profiles |
EP0226604B1 (de) * | 1985-05-29 | 1991-08-21 | Artificial Sensing Instruments ASI AG | Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahländerungen in messubstanzen |
US4838665A (en) * | 1986-07-25 | 1989-06-13 | Pioneer Electronic Corporation | Temperature-compensated lens system |
DE59410197D1 (de) * | 1993-03-26 | 2002-11-21 | Hoffmann La Roche | Optisches Verfahren und Vorrichtung zur Analyse von Substanzen an Sensoroberflächen |
GB9314991D0 (en) * | 1993-07-20 | 1993-09-01 | Sandoz Ltd | Mechanical device |
US5804380A (en) * | 1993-11-12 | 1998-09-08 | Geron Corporation | Telomerase activity assays |
US5671303A (en) * | 1996-04-17 | 1997-09-23 | Motorola, Inc. | Molecular detection apparatus and method using optical waveguide detection |
US6045259A (en) * | 1996-10-04 | 2000-04-04 | University Of South Florida | Fiber-optic high temperature sensor |
US5705821A (en) * | 1996-11-07 | 1998-01-06 | Sandia Corporation | Scanning fluorescent microthermal imaging apparatus and method |
US6327410B1 (en) * | 1997-03-14 | 2001-12-04 | The Trustees Of Tufts College | Target analyte sensors utilizing Microspheres |
US5971610A (en) * | 1997-04-16 | 1999-10-26 | Kolodner; Paul Robert | Fluorescent thermal imaging using rare-earth chelate films |
DE19900135A1 (de) * | 1998-01-07 | 1999-08-05 | Univ Rockefeller | Verfahren zur Bestimmung der Temperatur einer einzelnen Zelle in einer Zellprobe oder Gewebebiopsie sowie Verfahren zu dessen Verwendung |
WO1999035496A1 (en) * | 1998-01-08 | 1999-07-15 | Bioimage A/S | Method and apparatus for high density format screening for bioactive molecules |
AU5569699A (en) * | 1998-08-17 | 2000-03-06 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Identification of a region of the major surface glycoprotein ((msg)) gene of human (pneumocystis carinii) |
US6132958A (en) * | 1999-05-27 | 2000-10-17 | The Rockefeller University | Fluorescent bead for determining the temperature of a cell and methods of use thereof |
-
2001
- 2001-05-25 EP EP01401376A patent/EP1262764B1/de not_active Expired - Lifetime
- 2001-05-25 DE DE60127821T patent/DE60127821D1/de not_active Expired - Lifetime
-
2002
- 2002-05-22 US US10/154,465 patent/US20030012692A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030012692A1 (en) | 2003-01-16 |
EP1262764B1 (de) | 2007-04-11 |
EP1262764A1 (de) | 2002-12-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |