DE60109651D1 - Carnitin und huperzin enthaltende zusammensetzungen zur behandlung und vorbeugung von hyperaktivität mit aufmerksamkeitstörungen bei kindern - Google Patents
Carnitin und huperzin enthaltende zusammensetzungen zur behandlung und vorbeugung von hyperaktivität mit aufmerksamkeitstörungen bei kindernInfo
- Publication number
- DE60109651D1 DE60109651D1 DE60109651T DE60109651T DE60109651D1 DE 60109651 D1 DE60109651 D1 DE 60109651D1 DE 60109651 T DE60109651 T DE 60109651T DE 60109651 T DE60109651 T DE 60109651T DE 60109651 D1 DE60109651 D1 DE 60109651D1
- Authority
- DE
- Germany
- Prior art keywords
- huperzine
- prevention
- treatment
- carnitine
- children
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
- ZQPQGKQTIZYFEF-WCVJEAGWSA-N Huperzine Natural products C1([C@H]2[C@H](O)C(=O)N[C@H]2[C@@H](O)C=2C=CC=CC=2)=CC=CC=C1 ZQPQGKQTIZYFEF-WCVJEAGWSA-N 0.000 title 1
- 229960004203 carnitine Drugs 0.000 title 1
- 208000013403 hyperactivity Diseases 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
- UBAPRWGDQPSCEH-UHFFFAOYSA-N Des-N-methyl-beta-obscurine Natural products N1CCCC2C3CC(C)CC21C(C=CC(=O)N1)=C1C3 UBAPRWGDQPSCEH-UHFFFAOYSA-N 0.000 abstract 1
- 241001090156 Huperzia serrata Species 0.000 abstract 1
- ZRJBHWIHUMBLCN-SEQYCRGISA-N Huperzine A Natural products N1C(=O)C=CC2=C1C[C@H]1/C(=C/C)[C@]2(N)CC(C)=C1 ZRJBHWIHUMBLCN-SEQYCRGISA-N 0.000 abstract 1
- YYWGABLTRMRUIT-XHBSWPGZSA-N Huperzine B Natural products N1CCC[C@@H]2[C@@H]3C=C(C)C[C@]21C(C=CC(=O)N1)=C1C3 YYWGABLTRMRUIT-XHBSWPGZSA-N 0.000 abstract 1
- 208000020358 Learning disease Diseases 0.000 abstract 1
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 abstract 1
- ZRJBHWIHUMBLCN-UHFFFAOYSA-N Shuangyiping Natural products N1C(=O)C=CC2=C1CC1C(=CC)C2(N)CC(C)=C1 ZRJBHWIHUMBLCN-UHFFFAOYSA-N 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 235000013402 health food Nutrition 0.000 abstract 1
- ZRJBHWIHUMBLCN-YQEJDHNASA-N huperzine A Chemical compound N1C(=O)C=CC2=C1C[C@H]1\C(=C/C)[C@]2(N)CC(C)=C1 ZRJBHWIHUMBLCN-YQEJDHNASA-N 0.000 abstract 1
- 201000003723 learning disability Diseases 0.000 abstract 1
- ZRJBHWIHUMBLCN-BMIGLBTASA-N rac-huperzine A Natural products N1C(=O)C=CC2=C1C[C@@H]1C(=CC)[C@@]2(N)CC(C)=C1 ZRJBHWIHUMBLCN-BMIGLBTASA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001RM000218A ITRM20010218A1 (it) | 2001-04-23 | 2001-04-23 | Composizione per la prevenzione o il trattamento dei disturbi dell'apprendimento in bambini affetti da deficit dell'attenzione ed iperattivi |
| ITRM20010218 | 2001-04-23 | ||
| PCT/IT2001/000430 WO2002085341A2 (en) | 2001-04-23 | 2001-08-03 | Composition, containing carnitine and huperzin for the preventionor treatment of learning disorders in children suffering from attention deficit/hyperactive disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60109651D1 true DE60109651D1 (de) | 2005-04-28 |
| DE60109651T2 DE60109651T2 (de) | 2006-04-27 |
Family
ID=11455486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60109651T Expired - Fee Related DE60109651T2 (de) | 2001-04-23 | 2001-08-03 | Carnitin und huperzin enthaltende zusammensetzungen zur behandlung und vorbeugung von hyperaktivität mit aufmerksamkeitstörungen bei kindern |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20040058947A1 (de) |
| EP (1) | EP1383579B1 (de) |
| AT (1) | ATE291468T1 (de) |
| CA (1) | CA2436240A1 (de) |
| DE (1) | DE60109651T2 (de) |
| ES (1) | ES2237591T3 (de) |
| HU (1) | HUP0303963A3 (de) |
| IT (1) | ITRM20010218A1 (de) |
| MX (1) | MXPA03009631A (de) |
| PL (1) | PL367613A1 (de) |
| PT (1) | PT1383579E (de) |
| WO (1) | WO2002085341A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2390055B (en) | 2002-03-22 | 2005-09-07 | Cypher Science Internat Ltd | A marking apparatus |
| CN100441200C (zh) * | 2004-11-26 | 2008-12-10 | 谢德隆 | 石杉碱甲、乙复合成分的蛇足石杉提取物及其制备方法 |
| GB201205856D0 (en) * | 2012-04-02 | 2012-05-16 | Randall Jeremy A P | Food supplement to support brain function |
| CN102702101B (zh) * | 2012-05-23 | 2016-04-06 | 长沙市惠瑞生物科技有限公司 | 一种从千层塔中提取石杉碱甲的方法 |
| CN103667072B (zh) * | 2013-09-27 | 2016-04-13 | 浙江工业大学 | 一种蛇足石杉内生真菌及其在制备8α,15α-环氧化石杉碱甲的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998048785A2 (en) * | 1997-04-29 | 1998-11-05 | Kenneth Blum, Inc. | Allelic polygene diagnosis of reward deficiency syndrome and treatment |
| US5869528A (en) * | 1997-07-22 | 1999-02-09 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutical method for the treatment of attention-deficit/hyperactive disorders |
| US6964969B2 (en) * | 2001-04-19 | 2005-11-15 | Mccleary Edward Larry | Composition and method for treating impaired or deteriorating neurological function |
-
2001
- 2001-04-23 IT IT2001RM000218A patent/ITRM20010218A1/it unknown
- 2001-08-03 CA CA002436240A patent/CA2436240A1/en not_active Abandoned
- 2001-08-03 ES ES01961133T patent/ES2237591T3/es not_active Expired - Lifetime
- 2001-08-03 US US10/250,359 patent/US20040058947A1/en not_active Abandoned
- 2001-08-03 PT PT01961133T patent/PT1383579E/pt unknown
- 2001-08-03 EP EP01961133A patent/EP1383579B1/de not_active Expired - Lifetime
- 2001-08-03 MX MXPA03009631A patent/MXPA03009631A/es unknown
- 2001-08-03 PL PL01367613A patent/PL367613A1/xx unknown
- 2001-08-03 WO PCT/IT2001/000430 patent/WO2002085341A2/en active IP Right Grant
- 2001-08-03 DE DE60109651T patent/DE60109651T2/de not_active Expired - Fee Related
- 2001-08-03 HU HU0303963A patent/HUP0303963A3/hu unknown
- 2001-08-03 AT AT01961133T patent/ATE291468T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ITRM20010218A0 (it) | 2001-04-23 |
| WO2002085341A2 (en) | 2002-10-31 |
| US20040058947A1 (en) | 2004-03-25 |
| MXPA03009631A (es) | 2004-06-30 |
| PT1383579E (pt) | 2005-06-30 |
| HUP0303963A3 (en) | 2005-04-28 |
| EP1383579B1 (de) | 2005-03-23 |
| ITRM20010218A1 (it) | 2002-10-23 |
| ES2237591T3 (es) | 2005-08-01 |
| EP1383579A2 (de) | 2004-01-28 |
| HUP0303963A2 (hu) | 2004-04-28 |
| ATE291468T1 (de) | 2005-04-15 |
| DE60109651T2 (de) | 2006-04-27 |
| CA2436240A1 (en) | 2002-10-31 |
| PL367613A1 (en) | 2005-03-07 |
| WO2002085341A3 (en) | 2003-05-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |