DE60043958D1 - Modifizierte Virusoberflächenproteine, die an Tumorgefäßzellen binden - Google Patents
Modifizierte Virusoberflächenproteine, die an Tumorgefäßzellen bindenInfo
- Publication number
- DE60043958D1 DE60043958D1 DE60043958T DE60043958T DE60043958D1 DE 60043958 D1 DE60043958 D1 DE 60043958D1 DE 60043958 T DE60043958 T DE 60043958T DE 60043958 T DE60043958 T DE 60043958T DE 60043958 D1 DE60043958 D1 DE 60043958D1
- Authority
- DE
- Germany
- Prior art keywords
- viral
- vector particles
- modified
- surface protein
- virus vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108010052285 Membrane Proteins Proteins 0.000 title abstract 5
- 241000700605 Viruses Species 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 102000018697 Membrane Proteins Human genes 0.000 title 1
- 210000005167 vascular cell Anatomy 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 10
- 239000013598 vector Substances 0.000 abstract 9
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 6
- 230000003612 virological effect Effects 0.000 abstract 6
- 102400000368 Surface protein Human genes 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 239000013603 viral vector Substances 0.000 abstract 4
- 241000702421 Dependoparvovirus Species 0.000 abstract 2
- 108010003533 Viral Envelope Proteins Proteins 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 210000004779 membrane envelope Anatomy 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000001177 retroviral effect Effects 0.000 abstract 2
- 241001529453 unidentified herpesvirus Species 0.000 abstract 2
- 108010067390 Viral Proteins Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
- 210000005166 vasculature Anatomy 0.000 abstract 1
- 239000000277 virosome Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13045—Special targeting system for viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42927399A | 1999-10-29 | 1999-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60043958D1 true DE60043958D1 (de) | 2010-04-15 |
Family
ID=23702555
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60033951T Expired - Lifetime DE60033951T2 (de) | 1999-10-29 | 2000-10-27 | Modifizierte virale oberflächeproteine, welche an vaskulaturzellen eines tumor binden |
| DE60043958T Expired - Lifetime DE60043958D1 (de) | 1999-10-29 | 2000-10-27 | Modifizierte Virusoberflächenproteine, die an Tumorgefäßzellen binden |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60033951T Expired - Lifetime DE60033951T2 (de) | 1999-10-29 | 2000-10-27 | Modifizierte virale oberflächeproteine, welche an vaskulaturzellen eines tumor binden |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1224302B1 (de) |
| JP (1) | JP2003512074A (de) |
| AT (2) | ATE356879T1 (de) |
| AU (1) | AU1045701A (de) |
| CA (1) | CA2390081C (de) |
| DE (2) | DE60033951T2 (de) |
| IL (2) | IL149144A0 (de) |
| NZ (1) | NZ536851A (de) |
| WO (1) | WO2001031036A2 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070178066A1 (en) | 2003-04-21 | 2007-08-02 | Hall Frederick L | Pathotropic targeted gene delivery system for cancer and other disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5536814A (en) | 1993-09-27 | 1996-07-16 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| ATE388720T1 (de) * | 1997-04-10 | 2008-03-15 | Univ Southern California | Sich an extrazelluläre matrixbestandteile anbindende modifizierte proteine |
-
2000
- 2000-10-27 IL IL14914400A patent/IL149144A0/xx unknown
- 2000-10-27 NZ NZ536851A patent/NZ536851A/en unknown
- 2000-10-27 EP EP00971628A patent/EP1224302B1/de not_active Expired - Lifetime
- 2000-10-27 JP JP2001533171A patent/JP2003512074A/ja active Pending
- 2000-10-27 AT AT00971628T patent/ATE356879T1/de not_active IP Right Cessation
- 2000-10-27 WO PCT/IB2000/001567 patent/WO2001031036A2/en active IP Right Grant
- 2000-10-27 DE DE60033951T patent/DE60033951T2/de not_active Expired - Lifetime
- 2000-10-27 AT AT07004943T patent/ATE459722T1/de not_active IP Right Cessation
- 2000-10-27 AU AU10457/01A patent/AU1045701A/en not_active Abandoned
- 2000-10-27 DE DE60043958T patent/DE60043958D1/de not_active Expired - Lifetime
- 2000-10-27 CA CA2390081A patent/CA2390081C/en not_active Expired - Fee Related
- 2000-10-27 EP EP07004943A patent/EP1854892B1/de not_active Expired - Lifetime
-
2002
- 2002-04-15 IL IL149144A patent/IL149144A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1854892A1 (de) | 2007-11-14 |
| ATE459722T1 (de) | 2010-03-15 |
| EP1224302A2 (de) | 2002-07-24 |
| CA2390081C (en) | 2011-07-05 |
| DE60033951D1 (de) | 2007-04-26 |
| EP1854892B1 (de) | 2010-03-03 |
| WO2001031036A2 (en) | 2001-05-03 |
| AU1045701A (en) | 2001-05-08 |
| IL149144A0 (en) | 2002-11-10 |
| NZ536851A (en) | 2006-05-26 |
| EP1224302B1 (de) | 2007-03-14 |
| WO2001031036A9 (en) | 2002-11-14 |
| WO2001031036A3 (en) | 2001-11-22 |
| CA2390081A1 (en) | 2001-05-03 |
| ATE356879T1 (de) | 2007-04-15 |
| IL149144A (en) | 2010-12-30 |
| DE60033951T2 (de) | 2007-11-29 |
| JP2003512074A (ja) | 2003-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |