DE60039442D1 - Kommerzielle herstellung von chymosin in pflanzen - Google Patents

Kommerzielle herstellung von chymosin in pflanzen

Info

Publication number
DE60039442D1
DE60039442D1 DE60039442T DE60039442T DE60039442D1 DE 60039442 D1 DE60039442 D1 DE 60039442D1 DE 60039442 T DE60039442 T DE 60039442T DE 60039442 T DE60039442 T DE 60039442T DE 60039442 D1 DE60039442 D1 DE 60039442D1
Authority
DE
Germany
Prior art keywords
commercial production
chymosin
chymosine
plants
seed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60039442T
Other languages
English (en)
Inventor
Rooijen Gijs Van
Richard Glenn Keon
Joseph Boothe
Yin Shen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SemBioSys Genetics Inc
Original Assignee
SemBioSys Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SemBioSys Genetics Inc filed Critical SemBioSys Genetics Inc
Application granted granted Critical
Publication of DE60039442D1 publication Critical patent/DE60039442D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6483—Chymosin (3.4.23.4), i.e. rennin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23—Aspartic endopeptidases (3.4.23)
    • C12Y304/23004—Chymosin (3.4.23.4), i.e. rennin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE60039442T 1999-08-23 2000-08-23 Kommerzielle herstellung von chymosin in pflanzen Expired - Lifetime DE60039442D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37869699A 1999-08-23 1999-08-23
PCT/CA2000/000975 WO2001014571A1 (en) 1999-08-23 2000-08-23 Commercial production of chymosin in plants

Publications (1)

Publication Number Publication Date
DE60039442D1 true DE60039442D1 (de) 2008-08-21

Family

ID=23494182

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60039442T Expired - Lifetime DE60039442D1 (de) 1999-08-23 2000-08-23 Kommerzielle herstellung von chymosin in pflanzen

Country Status (7)

Country Link
EP (1) EP1216306B1 (de)
AT (1) ATE400661T1 (de)
AU (1) AU6678000A (de)
CA (1) CA2381438C (de)
DE (1) DE60039442D1 (de)
MX (1) MXPA02001904A (de)
WO (1) WO2001014571A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201900260T4 (tr) 2002-06-17 2019-02-21 Chr Hansen As Bir rekombinant konakçı organizmada bir aspartik proteaz üretmeye yönelik gelişmiş yöntem.
WO2005089040A2 (en) * 2004-03-23 2005-09-29 Chr. Hansen A/S Method of producing chymosin c and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD265164A1 (de) * 1987-09-09 1989-02-22 Akad Wissenschaften Ddr Verfahren zur herstellung proteinogener wirkstoffe
US5543576A (en) * 1990-03-23 1996-08-06 Mogen International Production of enzymes in seeds and their use
DK162790D0 (da) * 1990-07-06 1990-07-06 Novo Nordisk As Plantecelle
AU669478B2 (en) * 1991-04-09 1996-06-13 Unilever Plc Plant promoter involved in controlling lipid biosynthesis in seeds
NZ500736A (en) * 1997-04-25 2005-01-28 Sembiosys Genetics Inc Method for recovery of recombinantly produced polypeptides involving the cleavage of fusion proteins

Also Published As

Publication number Publication date
AU6678000A (en) 2001-03-19
EP1216306A1 (de) 2002-06-26
EP1216306B1 (de) 2008-07-09
ATE400661T1 (de) 2008-07-15
CA2381438A1 (en) 2001-03-01
CA2381438C (en) 2010-10-05
MXPA02001904A (es) 2002-10-31
WO2001014571A1 (en) 2001-03-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition