DE60033955D1 - Melanoma impfstoff und seine herstellung und verwendung - Google Patents
Melanoma impfstoff und seine herstellung und verwendungInfo
- Publication number
- DE60033955D1 DE60033955D1 DE60033955T DE60033955T DE60033955D1 DE 60033955 D1 DE60033955 D1 DE 60033955D1 DE 60033955 T DE60033955 T DE 60033955T DE 60033955 T DE60033955 T DE 60033955T DE 60033955 D1 DE60033955 D1 DE 60033955D1
- Authority
- DE
- Germany
- Prior art keywords
- vaccine
- cancer
- cells
- cell membranes
- melanoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229940115256 melanoma vaccine Drugs 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 5
- 210000000170 cell membrane Anatomy 0.000 abstract 3
- 210000000172 cytosol Anatomy 0.000 abstract 3
- 229960005486 vaccine Drugs 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 241000700618 Vaccinia virus Species 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 201000001441 melanoma Diseases 0.000 abstract 2
- 108010002350 Interleukin-2 Proteins 0.000 abstract 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 210000000612 antigen-presenting cell Anatomy 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 230000001024 immunotherapeutic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464484—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
- A61K39/464486—MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/46449—Melanoma antigens
- A61K39/464491—Melan-A/MART
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/46449—Melanoma antigens
- A61K39/464492—Glycoprotein 100 [Gp100]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464499—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55533—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/57—Skin; melanoma
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24093399P | 1999-10-18 | 1999-10-18 | |
US240933P | 1999-10-18 | ||
PCT/US2000/028837 WO2001028583A2 (en) | 1999-10-18 | 2000-10-18 | Melanoma vaccine and methods of making and using same |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60033955D1 true DE60033955D1 (de) | 2007-04-26 |
DE60033955T2 DE60033955T2 (de) | 2007-12-06 |
Family
ID=22908527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60033955T Expired - Fee Related DE60033955T2 (de) | 1999-10-18 | 2000-10-18 | Melanoma-impfstoff und seine herstellung und verwendung |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1227838B1 (de) |
JP (1) | JP2003512335A (de) |
AT (1) | ATE356632T1 (de) |
AU (1) | AU779325B2 (de) |
CA (1) | CA2387855A1 (de) |
DE (1) | DE60033955T2 (de) |
HK (1) | HK1049114A1 (de) |
IL (2) | IL149184A0 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005321898B2 (en) * | 2004-12-29 | 2012-07-19 | Mannkind Corporation | Use of compositions comprising various tumor-associated antigens as anti-cancer vaccines |
US10888594B2 (en) | 2016-05-30 | 2021-01-12 | National University Corporation Tottori University | Genetically engineered vaccinia viruses |
AU2017272721B2 (en) * | 2016-05-30 | 2023-03-30 | Astellas Pharma Inc. | Novel genetically engineered vaccinia viruses |
US20190336552A1 (en) | 2016-05-30 | 2019-11-07 | Astellas Pharma Inc. | Genetically engineered vaccinia viruses |
TWI824020B (zh) | 2018-09-26 | 2023-12-01 | 日商安斯泰來製藥股份有限公司 | 藉由腫瘤溶解性牛痘病毒與免疫檢查點抑制劑併用之癌症療法以及用於其之醫藥組合物及組合醫藥 |
-
2000
- 2000-10-18 IL IL14918400A patent/IL149184A0/xx unknown
- 2000-10-18 JP JP2001531411A patent/JP2003512335A/ja active Pending
- 2000-10-18 AU AU12140/01A patent/AU779325B2/en not_active Ceased
- 2000-10-18 AT AT00973647T patent/ATE356632T1/de not_active IP Right Cessation
- 2000-10-18 DE DE60033955T patent/DE60033955T2/de not_active Expired - Fee Related
- 2000-10-18 EP EP00973647A patent/EP1227838B1/de not_active Expired - Lifetime
- 2000-10-18 CA CA002387855A patent/CA2387855A1/en not_active Abandoned
-
2003
- 2003-02-07 HK HK03100947A patent/HK1049114A1/xx not_active IP Right Cessation
-
2008
- 2008-02-19 IL IL189615A patent/IL189615A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU779325B2 (en) | 2005-01-20 |
IL149184A0 (en) | 2002-11-10 |
EP1227838A2 (de) | 2002-08-07 |
JP2003512335A (ja) | 2003-04-02 |
DE60033955T2 (de) | 2007-12-06 |
IL189615A0 (en) | 2008-06-05 |
AU1214001A (en) | 2001-04-30 |
HK1049114A1 (en) | 2003-05-02 |
CA2387855A1 (en) | 2001-04-26 |
EP1227838B1 (de) | 2007-03-14 |
ATE356632T1 (de) | 2007-04-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20200261509A1 (en) | Vaccine compositions and methods | |
CN104056261B (zh) | 基于吲哚胺2,3-双加氧酶的免疫疗法 | |
US20080193487A1 (en) | Preparation for Vaccination, Vaccination Method and Use of a Vaccination Preparation | |
ES2529257T3 (es) | Vacuna basada en células B cargadas con el ligando de células T asesinas naturales y antígeno | |
Klimek et al. | Allergen immunotherapy in allergic rhinitis: current use and future trends | |
WO2007022151A3 (en) | Immunization of avians by administration of non-replicating vectored vaccines | |
NO20015073D0 (no) | Vaksiner | |
DK1778836T3 (da) | Fremstilling af antigenpræsenterende humane gammadelta-T-celler og anvendelse ved immunterapi | |
IL189615A0 (en) | Melanoma vaccine and methods of making and using same | |
AR068984A1 (es) | Proceso para la obtencion de celulas presentadoras de antigenos activados, utiles en las terapias contra el cancer y enfermedades relacionadas del sistema inmunologico | |
Dong et al. | Poria cocos polysaccharide induced Th1-type immune responses to ovalbumin in mice | |
CN105007930B (zh) | 用于治疗疾病的同种异体自噬体富集组合物 | |
CN103619350A (zh) | 包含组蛋白去乙酰化酶抑制剂的疫苗接种方法 | |
EP1556513A4 (de) | Zusammensetzungen und verfahren zurbehandlung von krankheiten, die durch das humane papillomavirus vermitteltwerden | |
WO2014139597A1 (en) | Method | |
WO2001028583A3 (en) | Melanoma vaccine and methods of making and using same | |
CA2340786C (en) | Vaccine comprising cytokine-induced heat shock proteins (hsp) | |
Guo et al. | Potent antigen-specific immune response induced by infusion of spleen cells coupled with succinimidyl-4-(N-maleimidomethyl cyclohexane)-1-carboxylate (SMCC) conjugated antigens | |
ES2316380T3 (es) | Complejos de un peptido y de una proteina de estres como vacunas contra patogenos intracelulares. | |
Sofra et al. | Antigen‐loaded ER microsomes from APC induce potent immune responses against viral infection | |
CO5300468A1 (es) | Antigeno asociado con tumores | |
WO2005039632B1 (en) | Colorectal cancer antigen | |
WO2005023295A3 (en) | Naturally processed immunodominant peptides derived from neisseria meningitidis porin a protein and their use | |
ITRM940461A1 (it) | Doppio sistema di vaccino contro il cancro c. d. bivaccino a specifico eterologo, entrambi naturali non sofisticati, polivalenti, entrambi proposti insieme alla cosi' detta biolinfa per la cura e la prevenzione del cancro |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |