DE60021069D1 - Identifizierung von essentiellen pilzspezifischen genen aus candida albicans sowie deren verwendung zur auffindung von antimycotika - Google Patents

Identifizierung von essentiellen pilzspezifischen genen aus candida albicans sowie deren verwendung zur auffindung von antimycotika

Info

Publication number
DE60021069D1
DE60021069D1 DE60021069T DE60021069T DE60021069D1 DE 60021069 D1 DE60021069 D1 DE 60021069D1 DE 60021069 T DE60021069 T DE 60021069T DE 60021069 T DE60021069 T DE 60021069T DE 60021069 D1 DE60021069 D1 DE 60021069D1
Authority
DE
Germany
Prior art keywords
essential
identification
candida albicans
antifungal
antimycotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60021069T
Other languages
English (en)
Inventor
Terry Roemer
Howard Bussey
John Davison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McGill University
Original Assignee
McGill University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McGill University filed Critical McGill University
Application granted granted Critical
Publication of DE60021069D1 publication Critical patent/DE60021069D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/40Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Candida
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
DE60021069T 1999-05-05 2000-05-05 Identifizierung von essentiellen pilzspezifischen genen aus candida albicans sowie deren verwendung zur auffindung von antimycotika Expired - Lifetime DE60021069D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13287899P 1999-05-05 1999-05-05
PCT/CA2000/000533 WO2000068420A2 (en) 1999-05-05 2000-05-05 Identification of candida albicans essential fungal specific genes and use thereof in antifungal drug discovery

Publications (1)

Publication Number Publication Date
DE60021069D1 true DE60021069D1 (de) 2005-08-04

Family

ID=22455994

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60021069T Expired - Lifetime DE60021069D1 (de) 1999-05-05 2000-05-05 Identifizierung von essentiellen pilzspezifischen genen aus candida albicans sowie deren verwendung zur auffindung von antimycotika

Country Status (10)

Country Link
US (1) US7129341B1 (de)
EP (1) EP1173619B1 (de)
JP (1) JP4842440B2 (de)
KR (1) KR20020047034A (de)
AT (1) ATE298803T1 (de)
AU (1) AU4531300A (de)
CA (1) CA2372854A1 (de)
DE (1) DE60021069D1 (de)
NZ (1) NZ515253A (de)
WO (1) WO2000068420A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1212459A2 (de) 1999-08-25 2002-06-12 Clarity Biosciences, Inc. Indentifizierung von organismen durch detektion intronischer nukleinsäuren oder kodierter proteine
US6783985B1 (en) 2000-02-18 2004-08-31 Elitra Pharmaceuticals Inc. Gene disruption methodologies for drug target discovery
US6562595B2 (en) * 2000-02-18 2003-05-13 Mcgill University Dominant selectable marker for gene transformation and disruption in yeasts

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194600A (en) 1990-03-05 1993-03-16 Royal Institute For The Advancement Of Learning Genes which participate in β-glucan assembly and use thereof
JPH09504176A (ja) 1993-10-25 1997-04-28 ライボジーン、インコーポレイテッド 抗真菌剤の選抜法
US5801015A (en) 1995-06-05 1998-09-01 Mitotix, Inc. Nucleic acid encoding a Candida cell cycle regulatory protein, TYP1 polypeptide
WO1999018213A1 (en) 1997-10-08 1999-04-15 Medical Research Council MUTANTS OF YEAST Cdc24p, DEFECTIVE IN BINDING OF THE G-PROTEIN BETA SUBUNIT
CA2218446A1 (en) * 1997-12-12 1999-06-12 Mcgill University New candida albicans kre9 and uses thereof
US6747137B1 (en) * 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics

Also Published As

Publication number Publication date
AU4531300A (en) 2000-11-21
KR20020047034A (ko) 2002-06-21
JP2002543799A (ja) 2002-12-24
NZ515253A (en) 2004-10-29
JP4842440B2 (ja) 2011-12-21
CA2372854A1 (en) 2000-11-16
WO2000068420A2 (en) 2000-11-16
ATE298803T1 (de) 2005-07-15
EP1173619B1 (de) 2005-06-29
WO2000068420A3 (en) 2001-04-05
US7129341B1 (en) 2006-10-31
EP1173619A2 (de) 2002-01-23

Similar Documents

Publication Publication Date Title
CA2492096A1 (en) Cis-alkoxy-substituted spirocyclic 1-h-pyrrolidine-2,4-dione derivatives serving as pesticides
ATE290004T1 (de) Bicyclische heterocyclen, verfahren zu ihrer herstellung und ihre verwendung als herbizide und pharmazeutische mittel
ATE355829T1 (de) Einen lipophilen wirkstoff enthaltende feste pharmazeutische zusammensetzung sowie deren herstellung
MX2007007458A (es) Derivados de quinazolina para inhibir crecimiento de celulas cancerigenas y metodo para la preparacion de los mismos.
UA86942C2 (ru) N-гетероциклилфенилзамещенные циклические кетоенолы и способ их получения
BRPI0415288A (pt) composto, composição farmacêutica, método para tratar ou prevenir doenças, e, método para preparar o composto
WO2003043631A3 (en) Method for identification of tumor targeting enzymes
WO2006102163A3 (en) Transfection reagents for non-adherent suspension cells
NO20055209D0 (no) Peptabody for cancerbehandling
WO2001089571A3 (en) Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives
EP2292255A3 (de) Stabile therapeutische Proteine
WO2006010084A3 (en) A system for delivering therapeutic agents into living cells and cell nuclei
DE502004008819D1 (de) Medikament zur wachstumsinhibierung von tumoren
DE60233395D1 (de) Die verwendung von abc transporter kodierenden genen zur stimulierung der herstellung von sekundärmetaboliten in biologischen zellen
DE60021069D1 (de) Identifizierung von essentiellen pilzspezifischen genen aus candida albicans sowie deren verwendung zur auffindung von antimycotika
AU2699595A (en) Screen for inhibitors of chitinase
DE60310742D1 (de) Extrakt mit antitumoraler und antitoxischer wirkung
BRPI0414786A (pt) extrato de mahonia aquifolium, processo de extração e composição farmacêutica contendo o mesmo
WO2000061551A3 (de) Pyrimidin-2-on derivate als integrinrezeptorliganden
EP1619195A3 (de) Verbindungen isoliert aus dem Gambogehartz, die als Inhibitore des Tumorzellwachstums wirken und pharmazeutische Zusammensetzungen enthalten
EP2757197A3 (de) Rückstrahlelemente und Artikel
WO2004054359A3 (en) Biological control agent and formulations
WO2005105832A3 (en) Biologically active peptide vapeehptllteaplnpk derivatives
AP2003002897A0 (en) Processes and intermediates for preparing benzyl epoxides
AU5219700A (en) Halopyrimidines

Legal Events

Date Code Title Description
8332 No legal effect for de