DE60002273T2 - Verfahren zur Reinigung von Diosmin - Google Patents

Verfahren zur Reinigung von Diosmin Download PDF

Info

Publication number
DE60002273T2
DE60002273T2 DE60002273T DE60002273T DE60002273T2 DE 60002273 T2 DE60002273 T2 DE 60002273T2 DE 60002273 T DE60002273 T DE 60002273T DE 60002273 T DE60002273 T DE 60002273T DE 60002273 T2 DE60002273 T2 DE 60002273T2
Authority
DE
Germany
Prior art keywords
diosmin
purification
phenolate
acidifying
recovering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60002273T
Other languages
English (en)
Other versions
DE60002273D1 (de
Inventor
Laurence Ferruccio
Dominique Gibert
Jean-Pierre Senet
Guyselaine Vergne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Isochem SAS
Original Assignee
Isochem SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isochem SAS filed Critical Isochem SAS
Application granted granted Critical
Publication of DE60002273D1 publication Critical patent/DE60002273D1/de
Publication of DE60002273T2 publication Critical patent/DE60002273T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/07—Benzo[b]pyran-4-ones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Removal Of Specific Substances (AREA)
  • Glass Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60002273T 1999-09-24 2000-09-01 Verfahren zur Reinigung von Diosmin Expired - Fee Related DE60002273T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9911964A FR2798932B1 (fr) 1999-09-24 1999-09-24 Procede de purification de la diosmine

Publications (2)

Publication Number Publication Date
DE60002273D1 DE60002273D1 (de) 2003-05-28
DE60002273T2 true DE60002273T2 (de) 2004-01-29

Family

ID=9550225

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60002273T Expired - Fee Related DE60002273T2 (de) 1999-09-24 2000-09-01 Verfahren zur Reinigung von Diosmin

Country Status (5)

Country Link
EP (1) EP1086953B1 (de)
AT (1) ATE238329T1 (de)
DE (1) DE60002273T2 (de)
ES (1) ES2195846T3 (de)
FR (1) FR2798932B1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2342338T3 (es) 2006-11-08 2010-07-05 Frans Nooren Afdichtingssystemen B.V. Proceso para proveer un articulo tubular extendido con un sistema de revestimiento de proteccion contra la corrosion con propiedades autorreparadoras.
RU2481353C1 (ru) * 2011-12-22 2013-05-10 Закрытое акционерное общество "Активный Компонент" Промышленный способ получения фармакопейного диосмина и его кристаллическая форма (варианты)
CN102875621A (zh) * 2012-10-26 2013-01-16 成都澜绮制药有限公司 地奥司明的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2740950A1 (de) * 1977-09-10 1979-03-22 Merck Patent Gmbh Verfahren zur herstellung von flavonen
FR2760016B1 (fr) * 1997-02-21 1999-05-28 Innokem Sarl Procede de fabrication industrielle de diosmine a partir de l'hesperidine
FR2760015B1 (fr) * 1997-02-21 1999-05-28 Innokem Sarl Procede de fabrication industrielle de diosmine a partir de l'hesperidine

Also Published As

Publication number Publication date
ES2195846T3 (es) 2003-12-16
FR2798932A1 (fr) 2001-03-30
FR2798932B1 (fr) 2001-12-07
DE60002273D1 (de) 2003-05-28
ATE238329T1 (de) 2003-05-15
EP1086953B1 (de) 2003-04-23
EP1086953A1 (de) 2001-03-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee