DE60001225D1 - Verfahren zur herstellung von epipodophyllotoxine-4'-demethyl-4'-phosphat-2",3"-bis pentafluorphenoxyacetyl-4",6"-ethyliden- beta-d-glucosid und seine salzen - Google Patents

Verfahren zur herstellung von epipodophyllotoxine-4'-demethyl-4'-phosphat-2",3"-bis pentafluorphenoxyacetyl-4",6"-ethyliden- beta-d-glucosid und seine salzen

Info

Publication number
DE60001225D1
DE60001225D1 DE60001225T DE60001225T DE60001225D1 DE 60001225 D1 DE60001225 D1 DE 60001225D1 DE 60001225 T DE60001225 T DE 60001225T DE 60001225 T DE60001225 T DE 60001225T DE 60001225 D1 DE60001225 D1 DE 60001225D1
Authority
DE
Germany
Prior art keywords
demethyl
beta
glucoside
phosphate
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60001225T
Other languages
English (en)
Inventor
Yves Guminski
Thierry Imbert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Application granted granted Critical
Publication of DE60001225D1 publication Critical patent/DE60001225D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/207—Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60001225T 1999-03-29 2000-03-29 Verfahren zur herstellung von epipodophyllotoxine-4'-demethyl-4'-phosphat-2",3"-bis pentafluorphenoxyacetyl-4",6"-ethyliden- beta-d-glucosid und seine salzen Expired - Lifetime DE60001225D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9903877A FR2791682B1 (fr) 1999-03-29 1999-03-29 Procede de preparation du 4'-demethyl-4'-phosphate-2", 3"-bis pentafluorophenoxyacetyl-4",6"-ethyldidene-beta-d- glucoside d'epipodophyllotoxine, et de ses sels
PCT/FR2000/000776 WO2000058324A1 (fr) 1999-03-29 2000-03-29 PROCEDE DE PREPARATION DU 4'-DEMETHYL -4'- PHOSPHATE-2',3' - BIS PENTAFLUOROPHENOXYACETYL -4',6' -ETHYLIDENE - β-D-GLUCOSIDE D'EPIPODOPHYLLOTOXINE, ET DE SES SELS

Publications (1)

Publication Number Publication Date
DE60001225D1 true DE60001225D1 (de) 2003-02-20

Family

ID=9543738

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60001225T Expired - Lifetime DE60001225D1 (de) 1999-03-29 2000-03-29 Verfahren zur herstellung von epipodophyllotoxine-4'-demethyl-4'-phosphat-2",3"-bis pentafluorphenoxyacetyl-4",6"-ethyliden- beta-d-glucosid und seine salzen

Country Status (7)

Country Link
EP (1) EP1165581B1 (de)
AT (1) ATE231157T1 (de)
AU (1) AU3661500A (de)
CA (1) CA2367442A1 (de)
DE (1) DE60001225D1 (de)
FR (1) FR2791682B1 (de)
WO (1) WO2000058324A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2859724B1 (fr) * 2003-09-16 2005-12-30 Pf Medicament Compose cristallin sous forme libre ou hemiethanolate de 4'-demethyl-4'-phosphate-2",3"-bispentafluorophenoxyacetyl- 4",6"-ethylidene-beta-d-glucoside d'epipodophyllotoxine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658824B1 (fr) * 1990-02-27 1992-07-03 Pf Medicament Tris acetyl-2",3",4' ethylidene-4",6" beta-d-glucopyranosides, leur preparation et leur utilisation pour la preparation d'ethylidene beta-d-glucopyranoside de demethyl-4' epipodophyllotoxine.
FR2725990B1 (fr) * 1994-10-21 1997-01-10 Pf Medicament Derives hydrosolubles d'epipodophyllotoxine, leur procede de preparation, leur utilisation a titre de medicament, et leur utilisation destinee aux traitements anticancereux

Also Published As

Publication number Publication date
ATE231157T1 (de) 2003-02-15
AU3661500A (en) 2000-10-16
WO2000058324A1 (fr) 2000-10-05
EP1165581A1 (de) 2002-01-02
EP1165581B1 (de) 2003-01-15
CA2367442A1 (fr) 2000-10-05
FR2791682B1 (fr) 2001-06-22
FR2791682A1 (fr) 2000-10-06

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Legal Events

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