DE59712333D1 - MICRO ELEMENT ASSEMBLY, METHOD FOR CONTACTING CELLS IN A LIQUID ENVIRONMENT, AND METHOD FOR PRODUCING A MICRO ELEMENTS ARRANGEMENT - Google Patents

MICRO ELEMENT ASSEMBLY, METHOD FOR CONTACTING CELLS IN A LIQUID ENVIRONMENT, AND METHOD FOR PRODUCING A MICRO ELEMENTS ARRANGEMENT

Info

Publication number
DE59712333D1
DE59712333D1 DE59712333T DE59712333T DE59712333D1 DE 59712333 D1 DE59712333 D1 DE 59712333D1 DE 59712333 T DE59712333 T DE 59712333T DE 59712333 T DE59712333 T DE 59712333T DE 59712333 D1 DE59712333 D1 DE 59712333D1
Authority
DE
Germany
Prior art keywords
micro
producing
element assembly
liquid environment
contacting cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59712333T
Other languages
German (de)
Inventor
Wilfried Nisch
Alfred Stett
Ulrich Egert
Martin Stelzle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytocentrics Ag 18059 Rostock De
Original Assignee
NMI Naturwissenschaftliches und Medizinisches Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NMI Naturwissenschaftliches und Medizinisches Institut filed Critical NMI Naturwissenschaftliches und Medizinisches Institut
Priority claimed from PCT/EP1997/006285 external-priority patent/WO1998022819A1/en
Application granted granted Critical
Publication of DE59712333D1 publication Critical patent/DE59712333D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G01N21/763—Bioluminescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electromagnetism (AREA)
  • Clinical Laboratory Science (AREA)
  • Mechanical Engineering (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE59712333T 1996-11-16 1997-11-11 MICRO ELEMENT ASSEMBLY, METHOD FOR CONTACTING CELLS IN A LIQUID ENVIRONMENT, AND METHOD FOR PRODUCING A MICRO ELEMENTS ARRANGEMENT Expired - Lifetime DE59712333D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19647525 1996-11-16
DE19712309A DE19712309A1 (en) 1996-11-16 1997-03-24 Microelement arrangement, method for contacting cells in a liquid environment and method for producing a microelement arrangement
PCT/EP1997/006285 WO1998022819A1 (en) 1996-11-16 1997-11-11 Array of microelements, method of contacting cells in a liquid environment and method for the production of an array of microelements

Publications (1)

Publication Number Publication Date
DE59712333D1 true DE59712333D1 (en) 2005-07-07

Family

ID=7811920

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19712309A Withdrawn DE19712309A1 (en) 1996-11-16 1997-03-24 Microelement arrangement, method for contacting cells in a liquid environment and method for producing a microelement arrangement
DE59712333T Expired - Lifetime DE59712333D1 (en) 1996-11-16 1997-11-11 MICRO ELEMENT ASSEMBLY, METHOD FOR CONTACTING CELLS IN A LIQUID ENVIRONMENT, AND METHOD FOR PRODUCING A MICRO ELEMENTS ARRANGEMENT

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19712309A Withdrawn DE19712309A1 (en) 1996-11-16 1997-03-24 Microelement arrangement, method for contacting cells in a liquid environment and method for producing a microelement arrangement

Country Status (1)

Country Link
DE (2) DE19712309A1 (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU746580B2 (en) 1997-12-17 2002-05-02 Ecole Polytechnique Federale De Lausanne Positioning and electrophysiological characterization of individual cells and reconstituted membrane systems on microstructured carriers
DE19827957C2 (en) * 1998-05-27 2000-06-29 Micronas Intermetall Gmbh Method and device for measuring a state variable
DE19841337C1 (en) 1998-05-27 1999-09-23 Micronas Intermetall Gmbh Intracellular manipulation of biological cell contents, assisting injection or removal of substances or cell components
GB9812783D0 (en) 1998-06-12 1998-08-12 Cenes Ltd High throuoghput screen
PL348035A1 (en) 1998-12-05 2002-05-06 Cenes Ltd Interface patch clamping
DE19907164C2 (en) 1999-02-19 2002-10-24 Micronas Gmbh Measuring device and method for its production
DE19924103C2 (en) * 1999-05-26 2002-12-19 Wolfram Seyfarth Device and / or method for determining and / or compensating electrical voltage states in a cell or cell assemblies
DE19948473A1 (en) 1999-10-08 2001-04-12 Nmi Univ Tuebingen Method and device for measuring cells in a liquid environment
US6692952B1 (en) 1999-11-10 2004-02-17 Massachusetts Institute Of Technology Cell analysis and sorting apparatus for manipulation of cells
JP2003514236A (en) * 1999-11-10 2003-04-15 マサチューセッツ・インスティテュート・オブ・テクノロジー Cell analysis and sorting equipment for manipulating cells
FR2802078B1 (en) 1999-12-14 2003-10-03 Univ Joseph Fourier MICROELECTRODE CELL SUPPORT WITH EXCITABLE MEMBRANE
GB9930719D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on an object in a m edium
GB9930718D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on objects
DE10023015A1 (en) * 2000-05-05 2002-01-24 Inst Chemo Biosensorik Process to produce a three-dimensional sensor element
DE10032568A1 (en) 2000-07-05 2002-01-24 Nmi Univ Tuebingen Device and method for electrically contacting biological cells suspended in a liquid
EP1178315A1 (en) * 2000-07-31 2002-02-06 Albrecht Dr.med. Priv.Doz. Lepple-Wienhues Method and apparatus for examining cells using the patch clamp method
WO2002059598A1 (en) * 2001-01-26 2002-08-01 Cytion S.A. Method and apparatus for the precise positioning of cells and other small objects
US6913697B2 (en) 2001-02-14 2005-07-05 Science & Technology Corporation @ Unm Nanostructured separation and analysis devices for biological membranes
DE10108968B4 (en) * 2001-02-16 2005-01-20 Multi Channel Systems Mcs Gmbh Device for performing electrophysiological measurements on cells
DE10128574A1 (en) * 2001-06-13 2003-01-02 Infineon Technologies Ag Device and method for manipulating vesicles
AU2003216175A1 (en) 2002-02-04 2003-09-02 Colorado School Of Mines Laminar flow-based separations of colloidal and cellular particles
US8895298B2 (en) 2002-09-27 2014-11-25 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
DE10251767A1 (en) * 2002-11-07 2004-05-27 Forschungszentrum Jülich GmbH Device and method for measuring electrical processes on biological membranes
EP1602922B1 (en) * 2003-03-07 2016-01-13 Panasonic Intellectual Property Management Co., Ltd. Extracellular potential measuring device and its manufacturing method
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US8119976B2 (en) 2007-07-03 2012-02-21 Colorado School Of Mines Optical-based cell deformability
US9487812B2 (en) 2012-02-17 2016-11-08 Colorado School Of Mines Optical alignment deformation spectroscopy
US9885644B2 (en) 2006-01-10 2018-02-06 Colorado School Of Mines Dynamic viscoelasticity as a rapid single-cell biomarker
US9878326B2 (en) 2007-09-26 2018-01-30 Colorado School Of Mines Fiber-focused diode-bar optical trapping for microfluidic manipulation
US10722250B2 (en) 2007-09-04 2020-07-28 Colorado School Of Mines Magnetic-field driven colloidal microbots, methods for forming and using the same
WO2010105728A2 (en) 2009-03-20 2010-09-23 Retina Implant Ag Active retinal implant
DE102009015389A1 (en) 2009-03-20 2010-09-30 Retina Implant Ag Active retinal implant for eye for serving to counteract loss of vision due to degenerations of retina, has array of stimulation elements that are designed as radiation-emitting elements
US9199080B2 (en) 2011-09-12 2015-12-01 Okuvision Gmbh Method for treating an eye
DE102013217694A1 (en) * 2013-09-04 2015-03-05 Cytocentrics Bioscience Gmbh Apparatus and method for measurement on membranes and cells
DE102014007424B8 (en) * 2014-05-22 2015-10-15 Forschungszentrum Jülich GmbH Apparatus and method for single cell analysis of microorganisms

Also Published As

Publication number Publication date
DE19712309A1 (en) 1998-05-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CYTOCENTRICS AG, 18059 ROSTOCK, DE