DE58908389D1 - Test carrier for the analytical determination of a component of a liquid sample. - Google Patents
Test carrier for the analytical determination of a component of a liquid sample.Info
- Publication number
- DE58908389D1 DE58908389D1 DE58908389T DE58908389T DE58908389D1 DE 58908389 D1 DE58908389 D1 DE 58908389D1 DE 58908389 T DE58908389 T DE 58908389T DE 58908389 T DE58908389 T DE 58908389T DE 58908389 D1 DE58908389 D1 DE 58908389D1
- Authority
- DE
- Germany
- Prior art keywords
- colour
- fluid
- sample
- layer
- colour forming
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000007788 liquid Substances 0.000 title 1
- 239000012530 fluid Substances 0.000 abstract 5
- 238000011156 evaluation Methods 0.000 abstract 3
- 239000002250 absorbent Substances 0.000 abstract 1
- 230000002745 absorbent Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/8483—Investigating reagent band
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
Abstract
Test strips for an analytical determination of a component in a fluid sample, in particular for the diagnosis of illnesses. Located on a base layer (2) are a sample receiving region (4) and an evaluation region (6) which are connected to one another by a fluid transporting section. Arranged in the evaluation region (6) is a colour forming layer (11) in which an optically detectable change that is characteristic for the analysis takes place.
<??>In order in the case of such a test strip to be able to control the orderly wetting of the test layers by means of longitudinal transport and thus to improve the dosing of the sample, there is arranged over the colour forming layer (11) in the evaluation region (6) an absorbent covering layer (7), which in the initial state of the test strip renders the colour of the colour forming layer (11) invisible. The covering layer (7) is in fluid contact with the fluid transporting section. The covering layer (7) and the colour forming layer (11) are constructed such that the colour of the colour forming reagent becomes visible when both layers are wetted by the sample fluid.
<IMAGE>
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3826057A DE3826057A1 (en) | 1988-07-30 | 1988-07-30 | TEST TESTER FOR THE ANALYTICAL DETERMINATION OF AN INGREDIENT OF A LIQUID SAMPLE |
Publications (1)
Publication Number | Publication Date |
---|---|
DE58908389D1 true DE58908389D1 (en) | 1994-10-27 |
Family
ID=6359987
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3826057A Withdrawn DE3826057A1 (en) | 1988-07-30 | 1988-07-30 | TEST TESTER FOR THE ANALYTICAL DETERMINATION OF AN INGREDIENT OF A LIQUID SAMPLE |
DE58908389T Expired - Fee Related DE58908389D1 (en) | 1988-07-30 | 1989-07-12 | Test carrier for the analytical determination of a component of a liquid sample. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3826057A Withdrawn DE3826057A1 (en) | 1988-07-30 | 1988-07-30 | TEST TESTER FOR THE ANALYTICAL DETERMINATION OF AN INGREDIENT OF A LIQUID SAMPLE |
Country Status (6)
Country | Link |
---|---|
US (1) | US5110550A (en) |
EP (1) | EP0353500B1 (en) |
JP (1) | JPH07104345B2 (en) |
AT (1) | ATE112057T1 (en) |
DE (2) | DE3826057A1 (en) |
ES (1) | ES2061812T3 (en) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4935346A (en) | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
DE3826056A1 (en) * | 1988-07-30 | 1990-02-01 | Boehringer Mannheim Gmbh | TEST TESTER FOR THE ANALYTICAL DETERMINATION OF AN INGREDIENT OF A LIQUID SAMPLE |
DE4015378A1 (en) * | 1990-05-14 | 1991-11-21 | Boehringer Mannheim Gmbh | TEST CARRIER FOR THE ANALYTICAL DETERMINATION OF A COMPONENT OF A SAMPLING LIQUID |
US5877028A (en) | 1991-05-29 | 1999-03-02 | Smithkline Diagnostics, Inc. | Immunochromatographic assay device |
US5607863A (en) | 1991-05-29 | 1997-03-04 | Smithkline Diagnostics, Inc. | Barrier-controlled assay device |
US5998220A (en) | 1991-05-29 | 1999-12-07 | Beckman Coulter, Inc. | Opposable-element assay devices, kits, and methods employing them |
US5468648A (en) | 1991-05-29 | 1995-11-21 | Smithkline Diagnostics, Inc. | Interrupted-flow assay device |
US6168956B1 (en) | 1991-05-29 | 2001-01-02 | Beckman Coulter, Inc. | Multiple component chromatographic assay device |
US5869345A (en) | 1991-05-29 | 1999-02-09 | Smithkline Diagnostics, Inc. | Opposable-element assay device employing conductive barrier |
US5686315A (en) * | 1991-06-14 | 1997-11-11 | Quidel Corporation | Assay device for one step detection of analyte |
DE4121493A1 (en) * | 1991-06-28 | 1993-01-07 | Draegerwerk Ag | ANALYSIS DEVICE FOR THE QUANTITATIVE, IMMUNOLOGICAL DETERMINATION OF POLLUTANTS |
DE4212280A1 (en) * | 1992-04-11 | 1993-10-14 | Boehringer Mannheim Gmbh | Asymmetrically porous membranes |
US5660798A (en) * | 1993-04-20 | 1997-08-26 | Actimed Laboratories, Inc. | Apparatus for red blood cell separation |
US5652148A (en) * | 1993-04-20 | 1997-07-29 | Actimed Laboratories, Inc. | Method and apparatus for red blood cell separation |
US5766552A (en) * | 1993-04-20 | 1998-06-16 | Actimed Laboratories, Inc. | Apparatus for red blood cell separation |
US5569608A (en) * | 1995-01-30 | 1996-10-29 | Bayer Corporation | Quantitative detection of analytes on immunochromatographic strips |
CA2167362A1 (en) * | 1995-02-10 | 1996-08-11 | Alexei Dmitri Klimov | Apparatus and method for conducting a binding assay on an absorbent carrier material |
AU5166198A (en) * | 1996-11-08 | 1998-05-29 | Mercury Diagnostics Inc. | Opaque reaction matrix for the analysis of whole blood |
US5879951A (en) | 1997-01-29 | 1999-03-09 | Smithkline Diagnostics, Inc. | Opposable-element assay device employing unidirectional flow |
US5939252A (en) | 1997-05-09 | 1999-08-17 | Lennon; Donald J. | Detachable-element assay device |
US6458326B1 (en) | 1999-11-24 | 2002-10-01 | Home Diagnostics, Inc. | Protective test strip platform |
US6534324B1 (en) * | 2000-05-12 | 2003-03-18 | Mizuho Usa, Inc. | Rapid assay strip and method of rapid competitive assay |
US6525330B2 (en) | 2001-02-28 | 2003-02-25 | Home Diagnostics, Inc. | Method of strip insertion detection |
US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
US6855561B2 (en) | 2001-09-10 | 2005-02-15 | Quidel Corporation | Method for adding an apparent non-signal line to a lateral flow assay |
EP1376131A1 (en) * | 2002-06-27 | 2004-01-02 | Inverness Medical Switzerland GmbH | Assay device for liquid sample |
DK1695094T3 (en) | 2003-10-24 | 2013-09-16 | Adhesives Res Inc | Disintegrating films for diagnostic devices |
WO2005095967A1 (en) * | 2004-03-23 | 2005-10-13 | Quidel Corporation | Hybrid phase lateral flow assay |
US20060029516A1 (en) * | 2004-08-09 | 2006-02-09 | General Electric Company | Sensor films and systems and methods of detection using sensor films |
US7189522B2 (en) | 2005-03-11 | 2007-03-13 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
WO2006098804A2 (en) | 2005-03-11 | 2006-09-21 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
CN101341407A (en) * | 2006-01-10 | 2009-01-07 | 因韦尔尼斯医药瑞士股份有限公司 | Apparatus and method for immune detection |
US7871568B2 (en) | 2006-01-23 | 2011-01-18 | Quidel Corporation | Rapid test apparatus |
US7794656B2 (en) | 2006-01-23 | 2010-09-14 | Quidel Corporation | Device for handling and analysis of a biological sample |
US20100022916A1 (en) | 2008-07-24 | 2010-01-28 | Javanbakhsh Esfandiari | Method and Apparatus for Collecting and Preparing Biological Samples for Testing |
US8603835B2 (en) | 2011-02-10 | 2013-12-10 | Chembio Diagnostic Systems, Inc. | Reduced step dual path immunoassay device and method |
US9528941B2 (en) | 2012-08-08 | 2016-12-27 | Scanadu Incorporated | Method and apparatus for determining analyte concentration by quantifying and interpreting color information captured in a continuous or periodic manner |
US9285323B2 (en) | 2012-08-08 | 2016-03-15 | Scanadu Incorporated | Quantifying color changes of chemical test pads induced concentrations of biological analytes under different lighting conditions |
US9311520B2 (en) | 2012-08-08 | 2016-04-12 | Scanadu Incorporated | Method and apparatus for performing and quantifying color changes induced by specific concentrations of biological analytes in an automatically calibrated environment |
EP2905607A1 (en) * | 2014-02-07 | 2015-08-12 | Nxp B.V. | Analyte detection methods and devices |
JP6686278B2 (en) * | 2014-02-28 | 2020-04-22 | 株式会社リコー | Inspection device, inspection kit, transfer medium, inspection device manufacturing method, and inspection method |
GB2548653A (en) | 2014-04-02 | 2017-09-27 | Chembio Diagnostic Systems Inc | Immunoassay utilizing trapping conjugate |
EP3180596A4 (en) | 2014-08-15 | 2018-09-26 | Scanadu Incorporated | Precision luxmeter methods for digital cameras to quantify colors in uncontrolled lighting environments |
US20160116466A1 (en) | 2014-10-27 | 2016-04-28 | Chembio Diagnostic Systems, Inc. | Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses |
CN108061732B (en) * | 2018-01-18 | 2023-06-30 | 重庆工商大学 | Wearable intelligent urine detection system and urine detection method |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2819645A1 (en) * | 1978-05-05 | 1979-11-08 | Merck Patent Gmbh | MEANS AND METHODS OF IMPLEMENTING COLORIMETRIC OR PHOTOMETRIC DETERMINATIONS |
US4292916A (en) * | 1979-06-18 | 1981-10-06 | Micro-Circuits Company | Timer and storage condition indicator |
DE3029579C2 (en) * | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Method and means for separating plasma or serum from whole blood |
DE3434822A1 (en) * | 1984-09-22 | 1986-04-03 | Bayer Ag, 5090 Leverkusen | MEMBRANE FOR REAGENT CARRIER LAYERS, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE IN ANALYTICAL AGENTS AND ANALYZING METHOD |
US4618533A (en) * | 1984-11-30 | 1986-10-21 | Millipore Corporation | Porous membrane having hydrophilic surface and process |
DE3445816C1 (en) * | 1984-12-15 | 1986-06-12 | Behringwerke Ag, 3550 Marburg | Flat diagnostic agent |
DE3446636A1 (en) * | 1984-12-20 | 1986-06-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD FOR PRODUCING AN IMMUNREACTIVE POROUS CARRIER MATERIAL |
DE3523439A1 (en) * | 1985-06-29 | 1987-01-08 | Boehringer Mannheim Gmbh | TEST CARRIER |
US4851210A (en) * | 1986-05-22 | 1989-07-25 | Genelabs Incorporated | Blood typing device |
US4935346A (en) * | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
DE3638654A1 (en) * | 1986-11-12 | 1988-05-26 | Boehringer Mannheim Gmbh | TEST CARRIER FOR ANALYTICAL DETERMINATION OF A COMPONENT OF A BODY LIQUID |
DE3643516A1 (en) * | 1986-12-19 | 1988-06-30 | Boehringer Mannheim Gmbh | TEST CARRIER FOR THE ANALYTICAL DETERMINATION OF INGREDIENTS OF BODY LIQUIDS |
US4891313A (en) * | 1988-01-21 | 1990-01-02 | Boehringer Manheim Corporation | Method for determination of a component of a sample |
DE3826056A1 (en) * | 1988-07-30 | 1990-02-01 | Boehringer Mannheim Gmbh | TEST TESTER FOR THE ANALYTICAL DETERMINATION OF AN INGREDIENT OF A LIQUID SAMPLE |
-
1988
- 1988-07-30 DE DE3826057A patent/DE3826057A1/en not_active Withdrawn
-
1989
- 1989-07-12 ES ES89112703T patent/ES2061812T3/en not_active Expired - Lifetime
- 1989-07-12 EP EP89112703A patent/EP0353500B1/en not_active Expired - Lifetime
- 1989-07-12 DE DE58908389T patent/DE58908389D1/en not_active Expired - Fee Related
- 1989-07-12 AT AT89112703T patent/ATE112057T1/en not_active IP Right Cessation
- 1989-07-25 US US07/384,726 patent/US5110550A/en not_active Expired - Fee Related
- 1989-07-31 JP JP1197022A patent/JPH07104345B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5110550A (en) | 1992-05-05 |
EP0353500A3 (en) | 1991-01-30 |
EP0353500A2 (en) | 1990-02-07 |
ATE112057T1 (en) | 1994-10-15 |
JPH0278934A (en) | 1990-03-19 |
JPH07104345B2 (en) | 1995-11-13 |
EP0353500B1 (en) | 1994-09-21 |
DE3826057A1 (en) | 1990-02-01 |
ES2061812T3 (en) | 1994-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: ROCHE DIAGNOSTICS GMBH, 68305 MANNHEIM, DE |
|
8339 | Ceased/non-payment of the annual fee |