DE50210030D1 - RESOLUTIONABLE NANO AND MICRO CAPSULES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE - Google Patents

RESOLUTIONABLE NANO AND MICRO CAPSULES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE

Info

Publication number
DE50210030D1
DE50210030D1 DE50210030T DE50210030T DE50210030D1 DE 50210030 D1 DE50210030 D1 DE 50210030D1 DE 50210030 T DE50210030 T DE 50210030T DE 50210030 T DE50210030 T DE 50210030T DE 50210030 D1 DE50210030 D1 DE 50210030D1
Authority
DE
Germany
Prior art keywords
production
resolutionable
nano
nanocapsules
microcapsules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE50210030T
Other languages
German (de)
Inventor
Panzner Steffen Dr
Essler Frank Dr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novosom AG
Original Assignee
Novosom AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7687420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE50210030(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novosom AG filed Critical Novosom AG
Priority to DE50210030T priority Critical patent/DE50210030D1/en
Application granted granted Critical
Publication of DE50210030D1 publication Critical patent/DE50210030D1/en
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0039—Coated compositions or coated components in the compositions, (micro)capsules
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38672—Granulated or coated enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to rapidly dissolvable nanocapsules and microcapsules, to a method for the production thereof and to the use of the nanocapsules and microcapsules in the field of diagnostics and therapy. The invention provides dissolvable nanocapsules and microcapsules, which comprise a colloidal template in an aqueous solution, and complementary charged polymers on the template, whereby at least one of the polymers is a polyampholyte that can be discharged or whose charge can be reversed by changing the pH value.
DE50210030T 2001-05-31 2002-05-31 RESOLUTIONABLE NANO AND MICRO CAPSULES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE Revoked DE50210030D1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE50210030T DE50210030D1 (en) 2001-05-31 2002-05-31 RESOLUTIONABLE NANO AND MICRO CAPSULES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10127526A DE10127526A1 (en) 2001-05-31 2001-05-31 Process for the preparation and dissolution of nano- and microcapsules
PCT/EP2002/006001 WO2002096551A1 (en) 2001-05-31 2002-05-31 Dissolvable nanocapsules and microcapsules, method for the production thereof and their use
DE50210030T DE50210030D1 (en) 2001-05-31 2002-05-31 RESOLUTIONABLE NANO AND MICRO CAPSULES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE

Publications (1)

Publication Number Publication Date
DE50210030D1 true DE50210030D1 (en) 2007-06-06

Family

ID=7687420

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10127526A Ceased DE10127526A1 (en) 2001-05-31 2001-05-31 Process for the preparation and dissolution of nano- and microcapsules
DE50210030T Revoked DE50210030D1 (en) 2001-05-31 2002-05-31 RESOLUTIONABLE NANO AND MICRO CAPSULES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE10127526A Ceased DE10127526A1 (en) 2001-05-31 2001-05-31 Process for the preparation and dissolution of nano- and microcapsules

Country Status (4)

Country Link
EP (1) EP1397200B1 (en)
AT (1) ATE360475T1 (en)
DE (2) DE10127526A1 (en)
WO (1) WO2002096551A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10157046A1 (en) * 2001-11-18 2003-06-12 Novosom Ag Nano and microcapsules comprising reactive polymers
EP2298358A1 (en) * 2002-05-06 2011-03-23 Alnylam Pharmaceuticals Inc. Methods for delivery of nucleic acids
KR20040012487A (en) * 2002-07-31 2004-02-11 롬 앤드 하스 캄파니 Triggered response compositions
WO2007051303A1 (en) 2005-11-02 2007-05-10 Protiva Biotherapeutics, Inc. MODIFIED siRNA MOLECULES AND USES THEREOF
CN101636480B (en) 2007-01-11 2014-04-09 诺维信公司 Particles comprising active compounds
SG144763A1 (en) * 2007-01-24 2008-08-28 Univ Singapore Reverse phase layer-by-layer encapsulation of highly water soluble materials
DE102007027850A1 (en) * 2007-06-13 2008-12-24 Beiersdorf Ag Cosmetic preparations comprise bola lipids and additionally antitranspirant and/or deodorant materials
CA2710713C (en) 2007-12-27 2017-09-19 Protiva Biotherapeutics, Inc. Silencing of polo-like kinase expression using interfering rna
AU2009236219B8 (en) 2008-04-15 2015-06-25 Arbutus Biopharma Corporation Silencing of CSN5 gene expression using interfering RNA
EP2113257A1 (en) * 2008-04-30 2009-11-04 Consorzio per il Centro di Biomedica Moleculare Scrl Polyelectrolyte with positive net charge for use as medicament and diagnostic for cancer
JP5661621B2 (en) 2008-07-07 2015-01-28 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ Enzyme composition comprising enzyme-containing polymer particles
US20130164380A1 (en) 2010-06-17 2013-06-27 Actogenix Nv Compositions and methods for treating inflammatory conditions
WO2013075132A1 (en) 2011-11-17 2013-05-23 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Therapeutic rna switches compositions and methods of use
US9035039B2 (en) 2011-12-22 2015-05-19 Protiva Biotherapeutics, Inc. Compositions and methods for silencing SMAD4
MX2014010016A (en) 2012-02-21 2015-06-05 Inst Nat Sante Rech Med Tim receptors as virus entry cofactors.
US20160015808A1 (en) 2012-02-21 2016-01-21 Institut National De La Sante Et De La Recherche Medicale (Inserm) Tam receptors as virus entry cofactors
JP2015524418A (en) 2012-07-27 2015-08-24 アンスティテュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル CD147 as a receptor for pili-mediated adhesion of Neisseria meningitidis to vascular endothelial cells
JP6089152B2 (en) 2013-12-13 2017-03-01 レスターシー エルエルシイＲｅｓｔｏｒｓｅａ， Ｌｌｃ Exfoliating hair retention promoting formulation
AU2015259509A1 (en) 2014-05-16 2016-11-24 Restorsea, Llc Biphasic cosmetic
SG11201702662UA (en) 2014-10-02 2017-04-27 Protiva Biotherapeutics Inc Compositions and methods for silencing hepatitis b virus gene expression
WO2016197132A1 (en) 2015-06-04 2016-12-08 Protiva Biotherapeutics Inc. Treating hepatitis b virus infection using crispr
WO2017019891A2 (en) 2015-07-29 2017-02-02 Protiva Biotherapeutics, Inc. Compositions and methods for silencing hepatitis b virus gene expression
GB201706762D0 (en) * 2017-04-28 2017-06-14 Givaudan Sa Improvements in or relating to organic compounds
US20200352913A1 (en) 2017-11-23 2020-11-12 INSERM (Institut National de la Santé et de la Recherche Médicale) New method for treating dengue virus infection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2143513T3 (en) * 1994-05-05 2000-05-16 Jurgen Schrezenmeir MICROCAPSULA, AS WELL AS A PROCESS AND APPARATUS TO PRODUCE IT.
DE19810965A1 (en) * 1998-03-13 1999-09-16 Aventis Res & Tech Gmbh & Co Nanoparticles comprising polyelectrolyte complex of polycation, polyanion and biologically active agent, especially useful for controlled drug release on oral administration
DE19907552A1 (en) * 1999-02-22 2000-08-31 Max Planck Gesellschaft New stable polyelectrolyte capsules of controllable permeability, prepared by coating template particles, useful e.g. for controlled drug release
DE10037707A1 (en) * 2000-08-02 2002-02-14 Max Planck Gesellschaft Encapsulating liquid droplets, useful for pharmaceuticals, dyes or plant-protection agents, comprises first forming a polyelectrolyte film at the phase boundary of an emulsion
PT1305109E (en) * 2000-08-02 2004-11-30 Max Planck Gesellschaft PRODUCTION OF POLYETHECTROLITE CAPSULES THROUGH SURFACE PRECIPITATION
AU2002215015A1 (en) * 2000-10-11 2002-04-22 Henkel Kommanditgesellschaft Auf Aktien Method for the inclusion of perfume oils in washing and cleaning agents or cosmetics

Also Published As

Publication number Publication date
EP1397200B1 (en) 2007-04-25
EP1397200A1 (en) 2004-03-17
DE10127526A1 (en) 2002-12-12
WO2002096551A1 (en) 2002-12-05
ATE360475T1 (en) 2007-05-15

Similar Documents

Publication Publication Date Title
DE50210030D1 (en) RESOLUTIONABLE NANO AND MICRO CAPSULES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE
DE50108907D1 (en) NANO CAPSULES WITH A POLYELECTROLYTHOLE
WO2004020783A8 (en) Delayed-gelation solution
AU2001283963A1 (en) Polysiloxane polymers, method for their production and the use thereof
EP1078690A3 (en) Method for producing monodispersed ion exchangers with chelating groups and the use thereof
DE50103245D1 (en) POLYELECTROLYTE CAPSULE PRODUCTION THROUGH SURFACE PRECIPITATION
DE60041214D1 (en) Composite particles and process for their preparation, aqueous dispersion for chemical mechanical polishing and process for the production of semiconductor devices
DE59806202D1 (en) AQUEOUS POWDER VARNISH DISPERSION, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE POWDER VARNISH DISPERSION RECEIVED
DE60102246D1 (en) SHELL METAL CATALYST AND A PRECURSOR THEREFOR, METHOD FOR THE PRODUCTION AND USE THEREOF OF THIS CATALYST
WO2005094230A3 (en) Hollow nanocrystals and method of making
WO2004047690A3 (en) Prosthetic spinal disc nucleus with elevated swelling rate
ATE544493T1 (en) MICRO CAPSULES WITH UV FILTER EFFECT AND METHOD FOR THEIR PRODUCTION
ATE427983T1 (en) BARIUM SULFATE, METHOD FOR THE PRODUCTION THEREOF AND ITS USE
DE50111753D1 (en) EPOTHILON SYNTHETIC COMPONENTS I: UNSYMMETRICALLY SUBSTITUTED ACYLOINS AND ACYLOOD DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE FOR THE PREPARATION OF EPOTHILONES AND EPOTHILONE DERIVATIVES
EP1078688A3 (en) Method for producing monodispersed anion exchangers
DE50104567D1 (en) METHOD FOR PRODUCING IRON OXIDE YELLOW PIGMENTS
DE502004012162D1 (en) ELECTROSTERLY STABILIZED AQUEOUS POLYURETHANE RESINS, PROCESS FOR THEIR PREPARATION AND THEIR USE
DE60141746D1 (en) HUMIDIFINKS CONTAINING ION-SENSITIVE, WATER-DISPERSIBLE POLYMERS, AND METHOD FOR THE PRODUCTION THEREOF
WO2005075530A3 (en) Method for the production of monodispersed ion exchangers containing pores
DE60223016D1 (en) SINTER-RESISTANT CATALYST MATERIAL AND METHOD FOR THE PRODUCTION THEREOF
ATE338777T1 (en) AQUEOUS COPOLYMER DISPERSION, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF
EP1323473A3 (en) Monodispersed anion exchanger
EP1132343A3 (en) Process for the preparation of iron oxide and its use
DE60010209D1 (en) ID card, and method and device for its production
ATE395092T1 (en) CEMENTABLE ENDOPROTHESES

Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation