DE497908C - Process for the preparation of nitrogen-containing anthraquinone derivatives - Google Patents

Process for the preparation of nitrogen-containing anthraquinone derivatives

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Publication number
DE497908C
DE497908C DEI27618D DEI0027618D DE497908C DE 497908 C DE497908 C DE 497908C DE I27618 D DEI27618 D DE I27618D DE I0027618 D DEI0027618 D DE I0027618D DE 497908 C DE497908 C DE 497908C
Authority
DE
Germany
Prior art keywords
preparation
anthraquinone derivatives
nitrogen
nitro
anthraquinone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEI27618D
Other languages
German (de)
Inventor
Dr Josef Stock
Dr Karl Wilke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IG Farbenindustrie AG
Original Assignee
IG Farbenindustrie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IG Farbenindustrie AG filed Critical IG Farbenindustrie AG
Priority to DEI27618D priority Critical patent/DE497908C/en
Application granted granted Critical
Publication of DE497908C publication Critical patent/DE497908C/en
Expired legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Description

Verfahren zur Darstellung von stickstoffbaltigen Anthrachinonderivaten Aus der Patentschrift 3 6o 42 2 ist ein Verfahren zur Darstellun von stickstoffhaltigen 9 g Anthrachinanderivate,a bekannt geworden, das darin besteht, daß man rauchende Schwefelsäure auf i-Nitro-2-alk-ylanthracl-änone oder deren Kernsubstitutionsprodukte einwirken läßt.Method for the preparation of nitrogen-containing anthraquinone derivatives From the patent specification 3 6o 42 2 a method for the preparation of nitrogen-containing 9 g anthraquinone derivatives, a has become known, which consists in that fuming sulfuric acid on i-nitro-2-alk-ylanthracl-änones or their Allow nuclear substitution products to act.

Es ist nun weiter gefunden worden, daß sich. diese Reaktion auch auf solche Anthrachinonderivate anwenden läßt, welche die a--Nitro-ß-al-kylgruppierung in o-Stellun- zueinander mehrmals im Molekül enthalten. So entstehen z. B. auf diese 'Weise aus den entsprechenden Dinitredimethylanthrachinonen unter Austritt von 2 Moleküle Wasser neue Verbindungen-, wahrscheinlich Anthrachi#nondüsoxazole, die als Zwischenprodukte für die Gewinnung von Farbstoffen wertvoll sind.It has now been further found that. this reaction too can use such anthraquinone derivatives, which the a - nitro-ß-alkyl group contained several times in the molecule in the o-position to one another. So arise z. B. on this 'From the corresponding dinitredimethylanthraquinones with the escape of 2 Molecules of water new compounds-, probably anthrachi # nondüsoxazole, the are valuable as intermediate products for the production of dyes.

Bei derEinwirkung v(Yxi rauchender Schwefelsäure auf Dinitroanthrachinone bilden sich bekanntlich im allgemeinen Nitromitrosooxyanthrachinone, indem zunächst ein Sauerstoff aus nur einer Nitrogruppe in den Kern verschoben wird (vgl. die Patentschrift io4 282, Kl. 22). Der Bildung der Isoxazole geht wohl eine ähnliche Wanderung von Nitrosauerstoff, hier aber in die o-ständige Seite-nkette unter Zwischenbildung von Nitrosoalkoholen' voraus. So entsteht nach der Patentschrift 36o 422, Beispiel 2, aus 1, 5-DinitrO-2-methyl-' anthrachinon besonders leicht ein 5-Nitro- 1-, 2-anthrachinonisoxazol: wobei also in normaler Weise nur eine L\Iitrogruppe umgewandelt wird und die zweite als solche erhalten bleibt. Es bildet sich nicht etwa unter Beteiligung beider Nitrogruppen ein iNitrosooxyanthrachinonisoxazol. Daher war es überraschend und keineswegs vorauszusehen, daß beide Nitrogiuppen eines Dinitroanthrachinons so leicht durch rauchende Schwefelsäure eine Umlag gerung erfahren würden, sobald zu jeder in o-Stellung sich eine Alk-ylgruppe befindet, z. B.: Beispiele i. io Gewichtsteile il, 5-Dini-troc#2, 6-dimethyr.-anthrachinon (vom Zersetzungspunkt über 35o', erhalten durch Nitrierung von 2,6-3)#imetliylanthrachinon vom Schmelzpunkt 239 bis 240' mit Salpeterschwefelsäure) werden unter raschem Rühren und guter Kühlung in ioo Gewichtsteile rauchende Schwefelsäure von 65 O/o Anhydrid-gehalt eingetragen. -Nach kurzem Nachrühren wird auf Eis ausgegossen, wobei sich- das Reaktionspro,dulkt, vermutlich Anthrachinon-1,2,5,6-düsoxazol, in braun-,-elben Flocken ausscheidet. In trockenem Zustande stellt es einbraungelbes Pulver dar, das in kalten Alkalien unlöslich ist. Die Farbe der Lösung in konzentrierter Schwefelsäure ist braungelb, zi 2. In gleicher Weise,erhält man, ausgehend von 1, 8 - Dinitro - 2, 7 - dimethylanthrachinon (vom Schmelzpunkt 298 bis 299' unter Zersetzulig, gewonnen durch Nitrierung, von 2,7-'Dimethylantbrachinon vom Schmelzpunkt 169'), ein olivbraunes Reaktionsprodukt,. das das Anthrachinon-I.2.8.7-,diisoxazol darstellen dürfte und dem Isomeren des Beispiels i ähnlich ist.When fuming sulfuric acid acts on dinitroanthraquinones, as is well known, nitromitrosooxyanthraquinones are generally formed by initially displacing an oxygen from only one nitro group into the nucleus (cf. patent specification IO4,282 , cl. 22). The formation of isoxazoles is probably similar migration of nitro oxygen, but here permanent o-in the side-nkette interposition formation of Nitrosoalkoholen 'ahead. the result according to the patent 36o 422, example 2, 1, 5-dinitro-2-methyl-' anthraquinone particularly easy a 5- Nitro-1-, 2-anthraquinone isoxazole: where normally only one nitro group is converted and the second is retained as such. An i-nitrosooxyanthraquinone isoxazole is not formed with the participation of both nitro groups. It was therefore surprising and by no means to be foreseen that both nitro groups of a dinitroanthraquinone would so easily undergo rearrangement by fuming sulfuric acid as soon as there is an alk-yl group to each in the o-position, e.g. B .: Examples i. 10 parts by weight of 5-dinotroc # 2, 6-dimethyr.-anthraquinone (from the decomposition point above 35o ', obtained by nitration of 2.6-3) #imetliylanthraquinone from melting point 239 to 240' with nitric sulfuric acid) are stirred rapidly and good cooling in 100 parts by weight of fuming sulfuric acid with an anhydride content of 65%. After a short further stirring, it is poured onto ice, with the reaction product, presumably anthraquinone-1,2,5,6-düsoxazole, precipitating in brown -, - yellow flakes. When dry it is a brownish-yellow powder, which is insoluble in cold alkalis. The solution color in concentrated sulfuric acid is brown yellow, zi 2. In the same way, is obtained, starting from 1, 8 - dinitro - 2, 7 - dimethylanthraquinone (of melting point 298-299 'under Zersetzulig obtained by nitration of 2, 7-'Dimethylantbrachinon with a melting point of 169'), an olive-brown reaction product. which should represent the anthraquinone-I.2.8.7-, diisoxazole and is similar to the isomer of Example i.

Claims (1)

PATENTAN SPRU CII. Verfahren zur Darstellung von stickstoffhaltigen Anthrachinonderivaten, dadurch gekennzeichnet, daß man rauchende Schwefelsäure auf solche Anthrachinonderivate einwirken läßt, welchediea-Nitro-P-alkylgruppierung in o-Stellung zueinander mehrn-ials im Molekül enthalten.PATENTAN SPRU CII. Process for the preparation of nitrogenous Anthraquinone derivatives, characterized in that fuming sulfuric acid is used such anthraquinone derivatives can act which the a-nitro-P-alkyl grouping in the o-position to one another contained more n-ials in the molecule.
DEI27618D 1926-03-09 1926-03-09 Process for the preparation of nitrogen-containing anthraquinone derivatives Expired DE497908C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEI27618D DE497908C (en) 1926-03-09 1926-03-09 Process for the preparation of nitrogen-containing anthraquinone derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEI27618D DE497908C (en) 1926-03-09 1926-03-09 Process for the preparation of nitrogen-containing anthraquinone derivatives

Publications (1)

Publication Number Publication Date
DE497908C true DE497908C (en) 1930-05-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DEI27618D Expired DE497908C (en) 1926-03-09 1926-03-09 Process for the preparation of nitrogen-containing anthraquinone derivatives

Country Status (1)

Country Link
DE (1) DE497908C (en)

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