DE464614C - Process for the preparation of an injection agent against tuberculosis - Google Patents

Process for the preparation of an injection agent against tuberculosis

Info

Publication number
DE464614C
DE464614C DEK96793D DEK0096793D DE464614C DE 464614 C DE464614 C DE 464614C DE K96793 D DEK96793 D DE K96793D DE K0096793 D DEK0096793 D DE K0096793D DE 464614 C DE464614 C DE 464614C
Authority
DE
Germany
Prior art keywords
garlic
preparation
against tuberculosis
agent against
injection agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEK96793D
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German (de)
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Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DEK96793D priority Critical patent/DE464614C/en
Application granted granted Critical
Publication of DE464614C publication Critical patent/DE464614C/en
Expired legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Description

Verfahren zur Herstellung eines Injektionsmittels gegen Tuberkulose Der Urfindung liegt die Feststellung zu-11rttnde, dar ein Auszug aus Zwiebeln, vorzugsweise Perlzwiebeln und Knoblauch, durch Injizieren unter die Haut oder in die Venen v in Heilmittel gegen Tuberkulose bildet, ohne nachteilige Nebenerscheinungen zu zeitigen. Bei (lern verbreiteten natürlichen Vorkommen des .Ausgangserzeugnisses stellt sich das Heilmittel äußerst billig, und seine GeENinnung ist besonders einfach.Process for the preparation of an injection agent against tuberculosis The original discovery is based on the finding that an extract from onions is preferred Pearl onions and garlic, injected under the skin or into the veins v in remedies for tuberculosis without causing any adverse side effects. In the case of widespread natural occurrences of the the remedy is extremely cheap, and it is particularly easy to collect.

Bisher haben die Knollenwurzeln der Laucharten, insbesondere von Allium scorodoprasum (Perlzwiebeln oder Rockenbollen, Knoblauch) in der Medizin lediglich zu schleimlösenden und harntreibenden Mitteln oder aber als Insektenvertilgungsmittel Verwendung gefunden. Wie indessen durch Tierversuche gefunden wurde, ist ein aus derartigen Knollengewächsen, namentlich Knoblauch, durch Trockendestillation gewonnener Auszug nach dem Reinigen geeignet, durch Einspritzen unter die Haut oder in die Venen Tuberkulose zu heilen.So far, the tuber roots of the leek species, especially allium scorodoprasum (pearl onions or rock balls, garlic) in medicine only to expectorants and diuretics or as an insecticide Use found. However, as has been found through animal experiments, one is off such tubers, namely garlic, obtained by dry distillation Extract suitable after cleaning, by injection under or into the skin Veins to cure tuberculosis.

Das Verfahren zur Herstellung eines Auszuges aus den Lauchknollengewächsen, beispielsweise Knoblauch, besteht in einer Trokkendestillation bei ioo bis 6oo°, darauffolgendem Abkühlen und Zurückbilden zu einem flüssigen Destillat, worauf dieses gefiltert und gereinigt wird. Eine geeignete Menge der so gewonnenen Flüssigkeit wird unter die Haut oder in die Venen eines Tuberkulösen eingespritzt, auf dessen Erkrankung sie heilend wirkt, ohne daß sich nachteilige Nebenerscheinungen zeigen.The process for producing an extract from the leek tuber family, for example garlic, consists of a dry distillation at 100 to 600 °, subsequent cooling and reforming to a liquid distillate, whereupon this is filtered and cleaned. A suitable amount of the liquid so obtained is injected under the skin or into the veins of a tuberculous, on the Disease it has a healing effect without showing any adverse side effects.

Außerdem bedingt die große Verbreitung des Ausgangserzeugnisses und die einfache Art seiner Behandlung eine billige Herstellung, die gerade in Anbetracht des Umfanges an Tuberkuloseerkrankungen besonders ins Gewicht fällt.In addition, the widespread use of the raw material and the simple nature of its treatment a cheap manufacture that just considering the extent of tuberculosis diseases is particularly important.

Die schließlich bei der Trockendestillation entfallende Flüssigkeit ist hellbraun und durchsichtig vom spezifischen Gewicht i,oi bis 1,o17° Be. Sie hat beizenden Geruch und Geschmack, reagiert schwach sauer und färbt Lackmuspapier etwas rot. Der wesentliche -Bestandteil der Lösung ist unbekannt, aber in Anbetracht dessen, daß der flüchtige Bestandteil von Knoblauch hauptsächlich ein Schwefel enthaltendes Öl ist, nämlich Knoblauchöl (C,H,),S, so steht anzunehmen, daß das Destillat Verbindungen oder Derivate dieses Öls enthält. Die Mutterlösung läßt sich nicht verflüchtigen und besteht vornehmlich aus einer in Wasser unlöslichen Flüssigkeit, einer geringen Menge an flüchtigen Bestandteilen und im übrigen aus Wasser. 0,2 bis 0,5 ccm dieser Lösung in zehnfacher Verdünnung, gemischt mit o, 5 % Karbolsäure, ergeben die für die Injektion geeignete Menge, die, wenn sie zwei- oder dreimal in der Woche unter die Haut eingespritzt wird, eine durch Versuche bestätigte Heilung von Tuberkulose hervorruft.The liquid that is finally eliminated in the dry distillation is light brown and transparent with a specific gravity of i, oi to 1, o17 ° Be. It has a pungent smell and taste, reacts slightly acidic and turns litmus paper a little red. The essential component of the solution is unknown, but considering that the volatile component of garlic is primarily a sulfur-containing oil, namely garlic oil (C, H,), S, the distillate is believed to be compounds or derivatives of this oil contains. The mother solution cannot be volatilized and consists primarily of a liquid which is insoluble in water, a small amount of volatile components and the rest of water. 0.2 to 0.5 cc of this solution, tenfold, mixed with 0.5% carbolic acid, gives the amount suitable for injection, which, when injected under the skin two or three times a week, is an experimental one proven cure for tuberculosis.

Beispiel. 3757g Knollen von wilden oder gezüchteten Perlzwiebeln (Allium scorodoprasuin) oder Knoblauch werden nach dem Waschen in Wasser in einer mit Kühlvorlage versehenen eisernen Retorte unter L uftabschluß allmählich erhitzt. Zuerst werden Wasser und flüchtige Bestandteile mit dem Ansteigen der Temperatur abgeschieden. Bei einer Temperatur von etwa 2oo° ist der Knoblauch gelöst und wird dann allmählich trockendestilliert. Beiiri Erreichen einer Endtemperatur von etwa 6oo° bleibt ein dunkelbraunes Destillat mit teerartigen Bestandteilen übrig. Dieser Bestandteil wird dann abgesondert und hierauf das Destillat so oft gefiltert, bis schließlich die Mutterlösung von hellbrauner Farbe gewonnen ist. Auf diese Weise können aus 3,757 g festem Knoblauch i,ooo g Mutterlösung erzielt werden.Example. 3757g Bulbs of wild or cultivated pearl onions (Allium scorodoprasuin) or garlic are after washing in water in a cooling template provided iron retort gradually heated with the exclusion of air. Be first Water and volatiles are deposited as the temperature rises. At a temperature of about 2oo ° the garlic is dissolved and then gradually becomes dry distilled. When a final temperature of about 600 ° is reached, a remains dark brown distillate with tarry components left over. This component is then separated and then the distillate is filtered so often until finally the mother liquor is obtained from light brown color. That way you can get out 3.757 g of solid garlic 1,000 g of mother liquor can be obtained.

Claims (1)

PATENTANSYRUCII.: Verfahren zur Herstellung eines Injektionsmittels gegen Tuberkulose aus Knollengewächsen der Läucharten, dadurch gekennzeichnet, daß diese Pflanzenstoffe, namentlich Perlzwiebeln (Allium scorodoprastim) und Knoblauch, bei einer Temperatur von ioo bis 6oo° trockendestilliert werden und das so gewonnene Destillat gefiltert und gereinigt wird.PATENTANSYRUCII .: Process for the manufacture of an injection device against tuberculosis from tubers of the leek species, characterized in that these plant substances, namely pearl onions (Allium scorodoprastim) and garlic, be dry-distilled at a temperature of 100 to 600 ° and the thus obtained Distillate is filtered and purified.
DEK96793D 1925-11-21 1925-11-21 Process for the preparation of an injection agent against tuberculosis Expired DE464614C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEK96793D DE464614C (en) 1925-11-21 1925-11-21 Process for the preparation of an injection agent against tuberculosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEK96793D DE464614C (en) 1925-11-21 1925-11-21 Process for the preparation of an injection agent against tuberculosis

Publications (1)

Publication Number Publication Date
DE464614C true DE464614C (en) 1928-08-21

Family

ID=7238474

Family Applications (1)

Application Number Title Priority Date Filing Date
DEK96793D Expired DE464614C (en) 1925-11-21 1925-11-21 Process for the preparation of an injection agent against tuberculosis

Country Status (1)

Country Link
DE (1) DE464614C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4024155A1 (en) * 1990-07-30 1992-02-06 Marcela Dipl Ing Holzhey Internal use of allicin-urotropin product - to treat bacterial, viral and fungal infections including meningitis, rabies, AIDs, tuberculosis, leprosy, plague and cancer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4024155A1 (en) * 1990-07-30 1992-02-06 Marcela Dipl Ing Holzhey Internal use of allicin-urotropin product - to treat bacterial, viral and fungal infections including meningitis, rabies, AIDs, tuberculosis, leprosy, plague and cancer

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