DE4420232A1 - Penetration depth checking device for hollow needle or probe inserted in human or animal patient - Google Patents

Penetration depth checking device for hollow needle or probe inserted in human or animal patient

Info

Publication number
DE4420232A1
DE4420232A1 DE4420232A DE4420232A DE4420232A1 DE 4420232 A1 DE4420232 A1 DE 4420232A1 DE 4420232 A DE4420232 A DE 4420232A DE 4420232 A DE4420232 A DE 4420232A DE 4420232 A1 DE4420232 A1 DE 4420232A1
Authority
DE
Germany
Prior art keywords
hollow needle
electrodes
probe
according
poles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE4420232A
Other languages
German (de)
Inventor
Robert Waltereit
Original Assignee
Robert Waltereit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Waltereit filed Critical Robert Waltereit
Priority to DE4420232A priority Critical patent/DE4420232A1/en
Publication of DE4420232A1 publication Critical patent/DE4420232A1/en
Application status is Withdrawn legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3401Puncturing needles for the peridural or subarachnoid space or the plexus, e.g. for anaesthesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3494Trocars; Puncturing needles with safety means for protection against accidental cutting or pricking, e.g. limiting insertion depth, pressure sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B7/00Measuring arrangements characterised by the use of electric or magnetic means
    • G01B7/26Measuring arrangements characterised by the use of electric or magnetic means for measuring depth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00022Sensing or detecting at the treatment site
    • A61B2017/00026Conductivity or impedance, e.g. of tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06Measuring instruments not otherwise provided for
    • A61B2090/062Measuring instruments not otherwise provided for penetration depth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/08Accessories or related features not otherwise provided for
    • A61B2090/0801Prevention of accidental cutting or pricking

Abstract

the device uses a pair of electrodes provided at the pointed end of the needle or probe, connected to oppose poles of an open current circuit, which converts an electromagnetic parameter value, e.g. the resistance, across these poles into a corresponding output signal. Pref. the electrodes extend from the pointed end of the needle or probe to the base of the latter at which they are connected to the open current circuit via a plug or socket connector, the output signal provided as an acoustic or optical feedback signal for the operator.

Description

Die Erfindung bezieht sich auf die Punktion von flüs sigkeitsgefüllten Hohlräumen im menschlichen Körper, wie es in der Medizin häufig notwendig ist; The invention relates to the puncture of FLÜS sigkeitsgefüllten cavities in the human body, as is often necessary in medicine; so zum Beispiel die Venenpunktion, die Punktion von Lymphkno ten und die Lumbalpunktion des Liquors. such as venipuncture, puncture of Lymphkno th and the lumbar puncture of cerebrospinal fluid.

Die Schwierigkeit bei der Punktion liegt bekannterma ßen darin, daß der Punkteur nicht mit eigenen Augen in den Patienten hineinsehen kann. The difficulty with the puncture is bekannterma SEN is that the Punkteur can not see into the patient with his own eyes. Zwei Größen sind dabei zu berücksichtigen: die Einstichrichtung und die Ein stichtiefe. Two sizes are to be considered: stich deep the puncture direction and On. Der erfahrene Arzt weiß um die Anatomie des zu punktierenden Körperteils zur Genüge, um die Kanüle an die richtige Stelle an der Körperoberfläche zu setzen und sie in der richtigen Richtung einzuste chen. The experienced doctor knows about the anatomy of the body part to be punctured sufficiently to set the needle to the right spot on the body surface and einzuste in the right direction chen. Die richtige Einstichtiefe erkennt er daran, daß beim Übergang vom Gewebe in den flüssigkeitsgefüllten Hohlraum der Reibungswiderstand geringer wird. The correct penetration depth he recognizes the fact that decreases in the transition from the fabric in the fluid-filled cavity of the frictional resistance. Bei schwierigen Punktionen, zum Beispiel der der Amnion flüssigkeit, ist es darüber hinaus gebräuchlich, die Position der Nadel mit Ultraschallaufnahmen zu überwa chen. In difficult punctures, for example, the amnion fluid, it is common beyond the position of the needle with ultrasound images to be monitored chen.

Dennoch, weil die eingangs genannte Schwierigkeit eben immer vorhanden bleibt, kommt es immer wieder zu miß glückten Punktionsversuchen, und dies nicht nur bei unerfahrenen Ärzten. Nevertheless, because the difficulty mentioned at the beginning is just always there, it always comes back to mis glückten puncture attempts, and not only with inexperienced doctors. Mehrfache Punktionsversuche stel len für Patient wie Arzt eine starke psychische Bela stung dar. Mißglücktes Punktieren kann zu Schäden beim Patienten führen. Multiple puncture tests Set ting for both patient and doctor a strong mental Bela stung represents. Unsuccessful puncturing may cause harm to the patient. Es können Hämatome entstehen, Gefäße können sich verschließen und andere iatrogene Schäden können auftreten. It can hematomas occur vessels can be closed and other iatrogenic damage may occur.

Die meisten Punktionen beziehen sich auf Flüssigkeiten im Körper. Most punctures refer to fluids in the body. Es ist bekannt, daß in Körpergeweben die Durchlässigkeit für Ionenströme geringer ist als in Körperflüssigkeiten, aufgrund der Behinderung der Io nenströme durch zelluläre Strukturen. It is known that in the body tissues, the permeability to ionic currents is smaller than in body fluids due to the obstruction of Io nenströme by cellular structures. Die elektrische Leitfähigkeit von Blut wird mit 0,0119 Siemens/cm angegeben (Documenta Geigy Wissenschaftliche Tabellen, 6. Aufl. 1960), was einem spezifischen Widerstand von ca. 83 Ohm * cm entspricht. The electrical conductivity of blood is given as 0.0119 Siemens / cm (Documenta Geigy Scientific Tables, 6th ed. 1960), which corresponds to a resistivity of approximately 83 Ohm * cm. Der spezifische Widerstand von Hirngewebe liegt bei 600 Ohm * cm, der von Tumor gewebe des Gehirns bei 200 Ohm * cm (R. Millner und R. Richwien, Grundlagen der Medizinischen Elektronik, Akad. Verlagsges. Frankfurt/Main 1969). The resistivity of brain tissue is 600 ohm * cm, the tumor tissue of the brain in 200 ohm * cm (R. Millner and R. Richwien, Basics of Medical Electronics, Akad. Verlagsges. Frankfurt / Main 1969). Dieser Erfin dung liegt die Idee zugrunde, an der Spitze der Punk tionskanüle zwei Elektroden anzubringen und den elek trischen Widerstand zwischen ihnen zu messen. This OF INVENTION-making is based on the idea tion cannula at the top of Punk to install two electrodes and measure the elec tric resistance between them. Beim Einstechen in den Körper sollte sich beim Übergang vom Gewebe in den flüssigkeitsgefüllten Hohlraum ein Un terschied im gemessenen Widerstand zwischen den Kanü lenelektroden ergeben, woraus sich die richtige Ein stichtiefe erkennen ließe. When inserted into the body should result in the transition from the fabric in the fluid-filled cavity, a Un terschied in the measured resistance between the Kanü lenelektroden itself, resulting in the correct An engraving depth could be seen.

In der Zeichnung ist ein Ausführungsbeispiel des Ge genstandes der Erfindung dargestellt. In the drawing, an embodiment of the Ge is illustrated tandes gene of the invention. Es zeigen: Show it:

Fig. 1 eine erfindungsgemäße Spritzenanordnung in der Seitenansicht und das angestochene Gewebe im Schnitt. Fig. 1 is a syringe assembly according to the invention in side view and the punctured tissue in the section. 1 und 2 sind übliche Einmalspritzen- Kolben und -Zylinder, 3 ist eine mit zwei Elek troden versehene Einmalkanüle, 4 ist ein Stec ker, der das optische und akustische Meßgerät 5 mit den Elektroden verbindet. 1 and 2 are conventional Einmalspritzen- pistons and cylinders, 3 is a trodes provided with two Elek disposable cannula, 4 is a Stec ker, which connects the optical and acoustic measuring device 5 with the electrodes. 6 ist das Gewebe, und 7 ist der flüssigkeitsgefüllte Hohlraum. 6 is the tissue, and 7 is the liquid-filled cavity. In Fig. 1 hat die Kanüle den Hohlraum noch nicht erreicht. In Fig. 1, the cannula has not yet reached the cavity.

Fig. 2 zeigt die Kanüle in der Flüssigkeit. Fig. 2 shows the cannula in the liquid. Das Meßge rät gibt ein optisches und ein akustisches Sig nal ab. The messge advises is an optical and an acoustic sig nal from.

Fig. 3 zeigt eine Spritze, die den Hohlraum bereits durchstochen hat. Fig. 3 shows a syringe which has pierced the cavity.

Fig. 4 zeigt einen Graphen, der die Signale der Fig. 1 bis 3 zusammenfaßt. Fig. 4 shows a graph summarizing the signals of FIG. 1 to 3.

Fig. 5 zeigt den Aufbau des Meßgerätes und den Aufbau der Kanüle (siehe auch Fig. 7). Fig. 5 shows the structure of the measuring device and the structure of the cannula (see also Fig. 7). Das Meßgerät ist ein Stromkreis, in den ein Signalanzeiger (im einfachsten Fall ein Widerstandsmesser) und eine Stromquelle eingebaut sind. The measuring instrument is a circuit in which a signal indicator (a resistance meter in the simplest case) and a power source are incorporated. Der Strom kann Gleichstrom, oder, zur Umgehung von Polarisati onseffekten, Wechselstrom sein. The current can direct current, or, onseffekten to circumvent polarization-be alternating current. 8 und 9 sind die beiden Pole des Meß-Stromkreises, die mit den Kanülenelektroden 11 und 10 der Kanüle 12 verbunden sind. 8 and 9 are the two poles of the measuring circuit, which are connected to the needle electrodes 11 and 10 of the cannula 12th Die Elektroden sind Beschich tungen der Außen- und Innenseite der Kanüle mit leitendem Material, wobei die Kanüle selbst nicht leiten soll. The electrodes are Beschich obligations the outside and inside of the cannula with a conductive material, wherein the cannula itself will not conduct. Um Pole und Elektroden leichter zu verbinden, ragt ein Segment der hier im Schnitt dargestellten Kanüle über die Kanülenbasis hinaus. To poles and easier to connect electrodes protrudes a segment of the cannula shown here in cross-section on the cannula base. Außen- und Innenelektrode sind so gut zugänglich für die Pole des Meß stromkreises. External and internal electrode are easily accessible to the poles of the measuring current circuit.

Fig. 6 zeigt die Kanüle in der Seitenansicht. Fig. 6 shows the cannula in the side view. An der Kanülenspitze kann man sehen, wie der nichtlei tende Kanülenkörper die beiden Elektroden trennt. At the needle tip can see how the nichtlei tend cannula body separates the two electrodes.

Fig. 7 zeigt einen Querschnitt durch die Kanüle. Fig. 7 shows a cross section through the cannula. Im Dreischichtenbau sieht man die nichtleitende Kanüle und die außen und innen aufgeschichteten Elektroden 15 und 14 auf 13 . In Dreischichtenbau one can see the non-conducting cannula and the exterior and interior stacked electrodes 15 and 14. 13

Fig. 8 zeigt eine Alternative in der Elektrodenkon struktion. Fig. 8 shows an alternative in the Elektrodenkon constructive tion. Auf dem Nichtleiter 16 sind die Elektroden 17 und 18 seitlich außen aufge schichtet. On the non-conductor 16, the electrodes 17 and 18 laminated laterally positioned outside.

Bei schwierigen oder bereits mißglückten Punktionen oder bei geringer Erfahrung auch sonst greift der Punkteur nun auf dieses erfindungsgemäße Gerät zurück. In difficult or previously unsuccessful punctures or little experience otherwise the Punkteur now draws on this inventive device. Mit Einschalten und Anstecken des Meßgerätes ist die Apparatur betriebsbereit. By turning on and plugging the meter, the apparatus is ready for operation. Punktiert wird wie gewohnt. Punctured as usual. Ein z. A z. B. tiefer Ton zeigt dem Punkteur, daß er sich noch oder schon wieder im Gewebe befindet. B. low tone shows the Punkteur that he is still or again in the tissue. Ein hoher Ton signalisiert, daß sich die Kanülenspitze in der Flüssigkeit befindet. A high tone signals that the cannula tip is in the liquid. Schon beim Einführen der Nadel erhält der Punkteur ein sicheres Signal, ob er sich in der Flüssigkeit befindet, und nicht erst beim Ansau gen. Even when inserting the needle of Punkteur provides a reliable signal, whether it is in the liquid, and not only when gen Ansau.

Claims (9)

1. Vorrichtung zur Prüfung der Eindringtiefe einer Hohlnadel, Sonde u. 1. A device for checking the depth of penetration of a hollow needle, probe u. dgl. in einen menschlichen oder tierischen Körper, dadurch gekennzeichnet, daß sich an der Spitze der Hohlnadel, Sonde u. the like. in a human or animal body, characterized in that u in the tip of the hollow needle probe. dgl. zwei Elektro den befinden, welche mit den beiden Polen eines zu diesen Polen hin offenen Stromkreises verbunden sind, der den elektrischen Widerstand oder eine andere elek tromagnetische Größe zwischen den beiden Polen in ein Signal umsetzt. the like. two electromagnets are the which are connected to the two poles of these poles open circuit, which converts the electrical resistance or other elec tromagnetic size between the two poles in a signal.
2. Hohlnadel, Sonde u. 2. hollow needle probe u. dgl. nach Anspruch 1, dadurch gekennzeichnet, daß die zwei Elektroden von der Spitze bis zur Basis der Hohlnadel, Sonde u. the like. according to claim 1, characterized in that the two electrodes of the tip to the base of the hollow needle, probe u. dgl. verlaufen und dort zur Verbindung mit dem Stromkreis vorzugswei se in einen Stecker bzw. in eine Buchse enden. the like extend. vorzugswei and there for connection to the circuit se terminate in a plug or in a socket.
3. Hohlnadel, Sonde u. 3. hollow needle probe u. dgl. nach Anspruch 2, bestehend aus nichtleitendem Material mit zwei Elektroden aus leitendem Material, diese entweder im nichtleitenden Material verlaufend oder auf das nichtleitende Mate rial aufgeschichtet. the like. according to claim 2, consisting of nonconductive material having two electrodes made of conductive material, these coated either to extend in non-conductive material or to the non-conductive mate rial.
4. Hohlnadel, Sonde u. 4. hollow needle probe u. dgl. nach Anspruch 2, bestehend aus drei Schichten: die äußere aus leitendem Material, die mittlere aus nichtleitendem und die innere aus leitendem Material. the like according to claim 2, consisting of three layers. The outer conductive material, the medium of non-conductive and the interior of conductive material. Handelt es sich um eine Hohlnadel, so liegt ihr Lumen in der inneren Schicht. If it is a hollow needle, so is its lumen in the inner layer.
5. Hohlnadel, Sonde u. 5. hollow needle probe u. dgl. nach Anspruch 2, welche zwei isolierte Elektroden umfaßt. the like. of claim 2, which comprises two insulated electrodes.
6. Stromkreis nach Anspruch 1, bestehend aus einer durch Gleich- oder Wechselspannung gespeisten Strom quelle, einem oder mehreren Signalanzeigern und den beiden Polen, die als Verbindungen mit den Elektroden vorzugsweise in einen Stecker bzw. in eine Buchse enden. 6. A circuit according to claim 1, consisting of a source powered by AC or DC power, one or more signal indicators and the two poles of which terminate as connections to the electrodes, preferably in a plug or in a socket.
7. Signalanzeiger nach Anspruch 1 und Anspruch 6, der die von den Elektroden kommende elektrische Information in akustische, optische oder andere Signale umsetzt. 7. Signal indicator according to claim 1 and claim 6, which converts the light coming from the electrodes electric information into acoustic, optical or other signals.
8. Akustischer Signalanzeiger nach Anspruch 7, der un terschiedlichen Leitungswiderstand zwischen den Elek troden in unterschiedliche Tonhöhen umsetzt. 8. Audible indicator according to claim 7, the un terschiedlichen line resistance between the elec trodes in different pitches reacted.
9. Hohlnadel nach Anspruch 4, dadurch gekennzeichnet, daß ein Segment der Hohlnadel über die Kanülenbasis hinausragt, damit beide Elektroden gut zugänglich sind (siehe Fig. 5 und Fig. 6). 9. hollow needle according to claim 4, characterized in that a segment of the hollow needle extends beyond the cannula base, so that both electrodes are accessible (see Fig. 5 and Fig. 6). Das Segment kann anschlie ßend noch nach außen gebogen sein. The segment can be subsequently ßend bent or outwardly.
DE4420232A 1994-06-07 1994-06-07 Penetration depth checking device for hollow needle or probe inserted in human or animal patient Withdrawn DE4420232A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE4420232A DE4420232A1 (en) 1994-06-07 1994-06-07 Penetration depth checking device for hollow needle or probe inserted in human or animal patient

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4420232A DE4420232A1 (en) 1994-06-07 1994-06-07 Penetration depth checking device for hollow needle or probe inserted in human or animal patient

Publications (1)

Publication Number Publication Date
DE4420232A1 true DE4420232A1 (en) 1995-12-14

Family

ID=6520218

Family Applications (1)

Application Number Title Priority Date Filing Date
DE4420232A Withdrawn DE4420232A1 (en) 1994-06-07 1994-06-07 Penetration depth checking device for hollow needle or probe inserted in human or animal patient

Country Status (1)

Country Link
DE (1) DE4420232A1 (en)

Cited By (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19640670A1 (en) * 1996-10-02 1998-05-07 Sueddeutsche Feinmechanik Bipolar electrode, especially for detection of nerve structure
WO1999007425A1 (en) * 1997-08-06 1999-02-18 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
EP0966922A1 (en) * 1998-06-27 1999-12-29 Heinrich Pajunk Unipolar cannula for continuous anaesthesia
US6171276B1 (en) 1997-08-06 2001-01-09 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
DE19914485C2 (en) * 1998-03-30 2002-10-24 Agilent Technologies Inc Apparatus and method for penetration with a shaft with a sensor for detecting the depth of penetration
US6478769B1 (en) * 2000-02-22 2002-11-12 The Board Of Trustees Of The University Of Arkansas Anatomical fluid evacuation apparatus and method
WO2002096486A1 (en) * 2001-05-31 2002-12-05 Neoseed Technology Llc Brachytherapy needle with impedance measurement apparatus and methods of use
WO2003037405A1 (en) * 2001-10-26 2003-05-08 Massachusetts Institute Of Technology Impedance sensor
WO2005025652A1 (en) * 2003-09-05 2005-03-24 Advanced Cardiovascular Systems, Inc. Systems and methods for detecting tissue contact and needle penetration depth using static fluid pressure measurements
US7022115B1 (en) 1999-11-11 2006-04-04 Gisela Meier Continuously conductive unipolar cannula for anesthesia
GB2418618A (en) * 2004-10-02 2006-04-05 Smiths Group Plc Tracheostomy apparatus
JP2007504907A (en) * 2003-09-12 2007-03-08 マイルストーン サイアンティフィック インク Drug infusion devices that were identified tissue using pressure sensing
US7364567B2 (en) 2002-06-10 2008-04-29 Abbott Cardiovascular Systems Inc. Systems and methods for detecting tissue contact and needle penetration depth
WO2009019707A1 (en) * 2007-08-08 2009-02-12 Impediguide Ltd. Tissue identification method and device
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7666149B2 (en) 1997-12-04 2010-02-23 Peliken Technologies, Inc. Cassette of lancet cartridges for sampling blood
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US7686799B2 (en) 2000-07-13 2010-03-30 Abbott Cardiovascular Systems Inc. Deployment system for myocardial cellular material
US7699791B2 (en) 2001-06-12 2010-04-20 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US7704231B2 (en) 2004-02-18 2010-04-27 Ares Trading S.A. Hand-held electronically controlled injection device for injecting liquid medications
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7731729B2 (en) 2002-04-19 2010-06-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
WO2010073134A1 (en) * 2008-12-22 2010-07-01 Koninklijke Philips Electronics, N.V. Contact detection tubes, methods and systems for medical procedures
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US7833171B2 (en) 2002-04-19 2010-11-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7841992B2 (en) 2001-06-12 2010-11-30 Pelikan Technologies, Inc. Tissue penetration device
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7862520B2 (en) 2002-04-19 2011-01-04 Pelikan Technologies, Inc. Body fluid sampling module with a continuous compression tissue interface surface
US7874994B2 (en) 2002-04-19 2011-01-25 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909775B2 (en) 2001-06-12 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909777B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7914465B2 (en) 2002-04-19 2011-03-29 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7959582B2 (en) 2002-04-19 2011-06-14 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8007446B2 (en) 2002-04-19 2011-08-30 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8079960B2 (en) 2002-04-19 2011-12-20 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US8308708B2 (en) 2003-07-15 2012-11-13 Abbott Cardiovascular Systems Inc. Deployment system for myocardial cellular material
US8333710B2 (en) 2002-04-19 2012-12-18 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8435190B2 (en) 2002-04-19 2013-05-07 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US8721671B2 (en) 2001-06-12 2014-05-13 Sanofi-Aventis Deutschland Gmbh Electric lancet actuator
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US8845549B2 (en) 2002-04-19 2014-09-30 Sanofi-Aventis Deutschland Gmbh Method for penetrating tissue
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9034639B2 (en) 2002-12-30 2015-05-19 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US9144401B2 (en) 2003-06-11 2015-09-29 Sanofi-Aventis Deutschland Gmbh Low pain penetrating member
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9560993B2 (en) 2001-11-21 2017-02-07 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9820684B2 (en) 2004-06-03 2017-11-21 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device

Cited By (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19640670A1 (en) * 1996-10-02 1998-05-07 Sueddeutsche Feinmechanik Bipolar electrode, especially for detection of nerve structure
DE19640670B4 (en) * 1996-10-02 2005-11-03 Süddeutsche Feinmechanik GmbH bipolar electrode
WO1999007425A1 (en) * 1997-08-06 1999-02-18 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
US6171276B1 (en) 1997-08-06 2001-01-09 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
US6547755B1 (en) 1997-08-06 2003-04-15 Pharmacia Ab Automated delivery device and method for its operation
US7666149B2 (en) 1997-12-04 2010-02-23 Peliken Technologies, Inc. Cassette of lancet cartridges for sampling blood
US8439872B2 (en) 1998-03-30 2013-05-14 Sanofi-Aventis Deutschland Gmbh Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
DE19914485C2 (en) * 1998-03-30 2002-10-24 Agilent Technologies Inc Apparatus and method for penetration with a shaft with a sensor for detecting the depth of penetration
EP0966922A1 (en) * 1998-06-27 1999-12-29 Heinrich Pajunk Unipolar cannula for continuous anaesthesia
US7022115B1 (en) 1999-11-11 2006-04-04 Gisela Meier Continuously conductive unipolar cannula for anesthesia
US6478769B1 (en) * 2000-02-22 2002-11-12 The Board Of Trustees Of The University Of Arkansas Anatomical fluid evacuation apparatus and method
US7686799B2 (en) 2000-07-13 2010-03-30 Abbott Cardiovascular Systems Inc. Deployment system for myocardial cellular material
US6709380B2 (en) * 2001-05-31 2004-03-23 Neoseed Technology Llc Brachytherapy needle with impedance measurement apparatus and methods of use
WO2002096486A1 (en) * 2001-05-31 2002-12-05 Neoseed Technology Llc Brachytherapy needle with impedance measurement apparatus and methods of use
US7981055B2 (en) 2001-06-12 2011-07-19 Pelikan Technologies, Inc. Tissue penetration device
US9694144B2 (en) 2001-06-12 2017-07-04 Sanofi-Aventis Deutschland Gmbh Sampling module device and method
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7909775B2 (en) 2001-06-12 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US7699791B2 (en) 2001-06-12 2010-04-20 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US8845550B2 (en) 2001-06-12 2014-09-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8721671B2 (en) 2001-06-12 2014-05-13 Sanofi-Aventis Deutschland Gmbh Electric lancet actuator
US8123700B2 (en) 2001-06-12 2012-02-28 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US8679033B2 (en) 2001-06-12 2014-03-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8382683B2 (en) 2001-06-12 2013-02-26 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9802007B2 (en) 2001-06-12 2017-10-31 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US8641643B2 (en) 2001-06-12 2014-02-04 Sanofi-Aventis Deutschland Gmbh Sampling module device and method
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US9937298B2 (en) 2001-06-12 2018-04-10 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8162853B2 (en) 2001-06-12 2012-04-24 Pelikan Technologies, Inc. Tissue penetration device
US8622930B2 (en) 2001-06-12 2014-01-07 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8016774B2 (en) 2001-06-12 2011-09-13 Pelikan Technologies, Inc. Tissue penetration device
US8360991B2 (en) 2001-06-12 2013-01-29 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8343075B2 (en) 2001-06-12 2013-01-01 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8282577B2 (en) 2001-06-12 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US8206319B2 (en) 2001-06-12 2012-06-26 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8216154B2 (en) 2001-06-12 2012-07-10 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7841992B2 (en) 2001-06-12 2010-11-30 Pelikan Technologies, Inc. Tissue penetration device
US7850622B2 (en) 2001-06-12 2010-12-14 Pelikan Technologies, Inc. Tissue penetration device
US8211037B2 (en) 2001-06-12 2012-07-03 Pelikan Technologies, Inc. Tissue penetration device
US8206317B2 (en) 2001-06-12 2012-06-26 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8246582B2 (en) 2001-10-26 2012-08-21 Massachusetts Institute Of Technology Microneedle transdermal transport device
US7651475B2 (en) 2001-10-26 2010-01-26 Massachusetts Institute Of Technology Microneedle transport device
US7645263B2 (en) 2001-10-26 2010-01-12 Massachusetts Institute Of Technology Impedance sensor
US7066922B2 (en) 2001-10-26 2006-06-27 Massachusetts Institute Of Technology Transdermal transport device with suction
WO2003037405A1 (en) * 2001-10-26 2003-05-08 Massachusetts Institute Of Technology Impedance sensor
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US7364568B2 (en) 2001-10-26 2008-04-29 Massachusetts Institute Of Technology Microneedle transdermal transport device
US9560993B2 (en) 2001-11-21 2017-02-07 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7959582B2 (en) 2002-04-19 2011-06-14 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9839386B2 (en) 2002-04-19 2017-12-12 Sanofi-Aventis Deustschland Gmbh Body fluid sampling device with capacitive sensor
US7909777B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7988644B2 (en) 2002-04-19 2011-08-02 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US8007446B2 (en) 2002-04-19 2011-08-30 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909774B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8062231B2 (en) 2002-04-19 2011-11-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8079960B2 (en) 2002-04-19 2011-12-20 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9724021B2 (en) 2002-04-19 2017-08-08 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7938787B2 (en) 2002-04-19 2011-05-10 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8197423B2 (en) 2002-04-19 2012-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8202231B2 (en) 2002-04-19 2012-06-19 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7874994B2 (en) 2002-04-19 2011-01-25 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7862520B2 (en) 2002-04-19 2011-01-04 Pelikan Technologies, Inc. Body fluid sampling module with a continuous compression tissue interface surface
US9498160B2 (en) 2002-04-19 2016-11-22 Sanofi-Aventis Deutschland Gmbh Method for penetrating tissue
US7833171B2 (en) 2002-04-19 2010-11-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9339612B2 (en) 2002-04-19 2016-05-17 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9186468B2 (en) 2002-04-19 2015-11-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9089294B2 (en) 2002-04-19 2015-07-28 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US8333710B2 (en) 2002-04-19 2012-12-18 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8337420B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7731729B2 (en) 2002-04-19 2010-06-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9089678B2 (en) 2002-04-19 2015-07-28 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8382682B2 (en) 2002-04-19 2013-02-26 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8388551B2 (en) 2002-04-19 2013-03-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus for multi-use body fluid sampling device with sterility barrier release
US8403864B2 (en) 2002-04-19 2013-03-26 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8414503B2 (en) 2002-04-19 2013-04-09 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US8430828B2 (en) 2002-04-19 2013-04-30 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US8435190B2 (en) 2002-04-19 2013-05-07 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US7914465B2 (en) 2002-04-19 2011-03-29 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9072842B2 (en) 2002-04-19 2015-07-07 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8905945B2 (en) 2002-04-19 2014-12-09 Dominique M. Freeman Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8690796B2 (en) 2002-04-19 2014-04-08 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8845549B2 (en) 2002-04-19 2014-09-30 Sanofi-Aventis Deutschland Gmbh Method for penetrating tissue
US8808201B2 (en) 2002-04-19 2014-08-19 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for penetrating tissue
US7364567B2 (en) 2002-06-10 2008-04-29 Abbott Cardiovascular Systems Inc. Systems and methods for detecting tissue contact and needle penetration depth
US8574195B2 (en) 2002-06-10 2013-11-05 Advanced Cardiovascular Systems, Inc. Systems and methods for detecting tissue contact and needle penetration depth using static fluid pressure measurements
US8177748B1 (en) 2002-06-10 2012-05-15 Advanced Cardiovascular Systems, Inc. Systems and methods for detecting tissue contact and needle penetration depth
US9034639B2 (en) 2002-12-30 2015-05-19 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8251921B2 (en) 2003-06-06 2012-08-28 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US9144401B2 (en) 2003-06-11 2015-09-29 Sanofi-Aventis Deutschland Gmbh Low pain penetrating member
US10034628B2 (en) 2003-06-11 2018-07-31 Sanofi-Aventis Deutschland Gmbh Low pain penetrating member
US8308708B2 (en) 2003-07-15 2012-11-13 Abbott Cardiovascular Systems Inc. Deployment system for myocardial cellular material
WO2005025652A1 (en) * 2003-09-05 2005-03-24 Advanced Cardiovascular Systems, Inc. Systems and methods for detecting tissue contact and needle penetration depth using static fluid pressure measurements
JP2007504907A (en) * 2003-09-12 2007-03-08 マイルストーン サイアンティフィック インク Drug infusion devices that were identified tissue using pressure sensing
JP4722849B2 (en) * 2003-09-12 2011-07-13 マイルストーン サイアンティフィック インク Drug infusion devices that were identified tissue using pressure sensing
US8945910B2 (en) 2003-09-29 2015-02-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US8296918B2 (en) 2003-12-31 2012-10-30 Sanofi-Aventis Deutschland Gmbh Method of manufacturing a fluid sampling device with improved analyte detecting member configuration
US9561000B2 (en) 2003-12-31 2017-02-07 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US7967784B2 (en) 2004-02-18 2011-06-28 Ares Trading S.A. Hand-held electronically controlled injection device for injecting liquid medications
US7704231B2 (en) 2004-02-18 2010-04-27 Ares Trading S.A. Hand-held electronically controlled injection device for injecting liquid medications
US8376985B2 (en) 2004-02-18 2013-02-19 Ares Trading S.A. Hand-held electronically controlled injection device for injecting liquid medications
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9261476B2 (en) 2004-05-20 2016-02-16 Sanofi Sa Printable hydrogel for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US9820684B2 (en) 2004-06-03 2017-11-21 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
GB2418618A (en) * 2004-10-02 2006-04-05 Smiths Group Plc Tracheostomy apparatus
GB2418618B (en) * 2004-10-02 2009-08-05 Smiths Group Plc Tracheostomy apparatus
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
WO2009019707A1 (en) * 2007-08-08 2009-02-12 Impediguide Ltd. Tissue identification method and device
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
WO2010073134A1 (en) * 2008-12-22 2010-07-01 Koninklijke Philips Electronics, N.V. Contact detection tubes, methods and systems for medical procedures
CN102292040A (en) * 2008-12-22 2011-12-21 皇家飞利浦电子股份有限公司 Contact detection tube method and system for medical procedures
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation

Similar Documents

Publication Publication Date Title
US3540447A (en) Spinal needle
US3516412A (en) Bipolar electrode having irregularity at inserting end thereof and method of insertion
EP0430929B1 (en) High-frequency surgical apparatus for thermally coagulating biological tissues
US5562503A (en) Bipolar adaptor for electrosurgical instrument
US5885219A (en) Interrogation device and method
EP1665983B1 (en) Device for determining impedance of the thorax
DE69535411T2 (en) Impedance meter for use as a tool for monitoring the state of health
Lenz et al. Methods for microstimulation and recording of single neurons and evoked potentials in the human central nervous system
DE4339049C2 (en) Device for configuration surgical systems
DE60221347T2 (en) In-situ adapter for an analyte test device
US6678550B2 (en) Multi electrode and needle injection device for diagnosis and treatment of muscle injury and pain
EP1032307B1 (en) Analytic measuring device with a puncturing aid
DE69725491T2 (en) Instrument with a common therapy and data access point
DE3218938C2 (en)
EP0126814A1 (en) Electro-surgical unit control apparatus
US4616660A (en) Variable alternating current output nerve locator/stimulator
DE3390003C2 (en)
US5196015A (en) Procedure for spinal pedicle screw insertion
DE69510064T3 (en) Ablation device with multiple electrodes
DE69733836T2 (en) A device for body fluid sampling and analysis
DE60026437T2 (en) Apparatus for use in assessing the level of an affected body part
EP0369414A1 (en) Dental anesthesia apparatus
US6796985B2 (en) Method for drilling bone, in particular for setting a pedicle screw, equipment, instrument and control device for implementing said method
EP2481338A2 (en) System for performing surgical procedures and assessments
US4032738A (en) Electro-surgical instrument

Legal Events

Date Code Title Description
8122 Nonbinding interest in granting licences declared
8139 Disposal/non-payment of the annual fee