DE3913120A1 - Solid compsns. contg. active agent for skin - comprising active material, e.g. cosmetic pigment or physiological agent, and water soluble binder contg. wax, fat or oil like substance - Google Patents

Abstract

Substances in the solid state intended for application toe the skin, comprising an active agent, (I) which has a desired effect after applicaton to the skin, opt. fillers and a binder which contains or consists exclusively of a wax-, fat- or oil-like substance (II), the overall binder being soluble in water. USE/ADVANTAGE - The prods. are esp. useful for the prodn. of stick-type applicators of the type used for application of lipstick, eyeliner, eyeshadow, makeup, insect repellents, sun protection agents, cosmetics, etc. to the skin. The binder give stick type prods. with high mechanical strength, shear resistance, drop break resistance, and resistance to high temps. The active substance (I) may be e.g. (in)organic cosmetic pigments, pearl gloss agents, metal powders, physiologically active substances such as painkillers (acetyl salicylic acid) antiphlogistic and cooling agents (bisabolol, camomile, menthol), disinfecting, antiobiotic substances, etc.

Description

The present invention relates to a solid Condition substance for application to the skin and a process for its production.

There are different types of substances that stand out are in a solid state and which are are true to be applied to the skin. Ins special is here, for example, on lipsticks, Eyeliner, eyeshadow pencils and make-ups, which are made of a container e.g. B. with the fingertip on the skin to be upset to think. But also in medical The areas are in a solid state Substances for application to the skin widely used. Think, for example, of mosquito pens or the same. After all, there are also skin care substances widely used, which also as a solid substance the skin surface are applied. Examples of this are sun protection lipsticks, colored UV filters in Stick shape, lip care sticks or the like.

All these substances have in common that they consist of one Active agent to produce a desired effect after the application to the skin, from fillers as well a binder.

Fat-based cosmetic pencils (lipsticks, lipliners, eyeliner) are already known from the prior art. These pens work on the principle of material removal by melting at body temperature. This has the disadvantage that such pens or substances are very sensitive to heat. In addition, the spread has an oily, greasy appearance, which is perceived by consumers as disadvantageous. Furthermore, pens are known whose material is removed only by abrasion. However, this type of pen is extremely fragile. In addition, there are already pens whose composition contains a paste-like binder in order to hold the pen together mechanically. This paste-like binder must be present in dissolved form in the wet raw mass when the pin is shaped (e.g. extrusion). Such raw materials therefore require a drying process after the mechanical shaping, which is relatively lengthy (days - weeks) and expensive (capital tied up by goods, space requirements, energy costs) and there is also the risk of hairline cracking and microbial contamination (mold, bacteria, etc.). In addition, the final dimension of such a shape is difficult to calculate due to the drying shrinkage.

An object of the present invention is now a substance in a solid state for Apply to the skin to create after the Shaping does not necessarily need to be dried, which is sharply contoured and locally remaining Guaranteed application of the substance to the skin and which is still one even at excessive temperatures has sufficient durability.

This object is achieved in that the binder is a wax, and / or fat and / or contains or exclusively includes oily substance and the binder as a whole is readily water-soluble. By briefly moistening the substance can be a non-oily  or not greasy shiny job to achieve enable sharp contours on the skin. Which he Substance according to the invention has the advantage that a Melting through the skin or body temperature of the Substance is no longer required. This will make the Possibility created in higher melting components larger amount to use, what compared to conventional Fat-based substances were not possible. Hereby the temperature stability is excellent as well as very good mechanical stability. By the ink-like wet application with subsequent drying matt films are created that are as well as powder pens an unprecedented dry have smudge resistance.

Compared to conventional powder sticks, whose removal by mechanical abrasion occurs on the skin and what therefore - as already mentioned at the beginning - not a high one The bandage can have mechanical strength Theoretically, the proportion of the medium in the subject of the application limits to be high because the removal by one physical solution process is guaranteed.

Furthermore, the substance according to the invention offers a very high level Point strength (torsional strength), compressive strength resistance to bending and falling resistance compared to the known pencil substances. this makes possible it, on protective measures like sheathing the substance (Mines) for example with a tubular film to breed.

An expedient embodiment of the sub according to the invention stamping is characterized in that the amount of Wax, fat or oily substance 25-65, related on the total weight. The invention grant  thus performs what the fat, wax, and oil-like Ingredients are very lean in composition (Lower limit 25%). On the one hand, this makes them very high Pigmentation layers, on the other hand, are not dry greasy, non-oily appearance of the application realizable.

The amount of wax, fat or oily substance 28-42% by weight based on the total weight.

It proves to be particularly advantageous if the wax, fat or oily substance at least 3/10, preferably 6/10 from non-ionic, well water-soluble material.

An expedient embodiment of the invention Substance is characterized in that it is well water soluble material made of polyethylene glycol and / or poly propylene glycol or at least one of the has both components.

Polypropylene glycol and / or poly is preferred ethylene glycol with a molecular weight between 200 - 6000 used.

Expediently, the readily water-soluble material but also a synthetic, non-ionic W / O Emulsifier include or be exclusively from this stand, which has a neutral pH and has an HLB value equal to or greater than 13.

Conveniently, as a synthetic, not ionic W / O emulsifier an ester of an organic Acid with polyethylene glycol or a poly  ethylene oxide adduct with an organic acid or with an organic alcohol can be used.

Another useful embodiment of the Invention contemporary substance is characterized in that the wax, fat or oily substance at least 3/10 consists of substances with a melting point above 70 ° C. This makes a particularly high temperature resistance guaranteed substance. The substance suffers consequently in sunlight, body temperature etc. no liquefaction or deformation, as with be often knew cosmetic pencils or the like watch is.

Alternatively, the wax, fat or oil type Substance at least 6/10 from substances with a Melting point above 45 ° C exist.

If, according to an expedient embodiment of the present invention, colorants are provided as active agents, the substance according to the invention can be used as a cosmetic substance, for . B lipstick substance, make-up, blush, eyeshadow pencil etc. can be used. The substance according to the invention generally has the advantage that it can be used without restriction in the cosmetics sector.

Organic colorants can expediently be used as colorants and / or inorganic cosmetic pigments, pearlescent agents especially like titanium dioxide coated mica, Metal powder of aluminum, silver, gold alone or in Combination with each other can be provided.

A configuration of the The present invention is characterized in that provided as an active ingredient physiologically active substances  are. Thus, the substance according to the invention can also be used the pharmaceutical sector, in particular then, if necessary, one in solid form apply lying medicines to the skin. Man think of painkillers in pen form, disinfection pens, hemostatic pens and the like.

Expediently, the claims set out in claim 14 counted funds alone or in combination as Physiologically active agents can be provided.

Furthermore, according to a further expedient staltung the present invention as an active ingredient skin protective and / or skin-care substances provided be. The substance according to the invention can thus be used ver as a sunscreen stick or the like turn. The suitable skin-protecting and / or skin care substances, which act as active ingredients alone or are provided in combination are in claim 16 listed.

The substance expediently has on application the skin pin shape or lead shape. Because of the out recorded mechanical and thermal properties the substance of the invention are a protective measure took, like sheathing the pen or one from the Substance existing mines in themselves superfluous.

The present invention further relates to a ver drive to manufacture the substance to order on the Skin. The inventive method is that one  

• a) the active ingredients and the fillers are mixed beforehand, preferably kneads;
• b) then the wax, fat and / or oil-like Adding substance;
• c) at least step (b) with an increased Temperature, preferably in the range of about 100 ° C. carries out; and
• d) the mixture when the desired homo is reached cools down to room temperature.

The method has the advantage that it can be automated in a simple manner and continuous cost-saving process the end product can be manufactured. In particular, it's not him required, the final moldings a separate firing process to undergo.

This enables a particularly homogeneous mixture suffice that the wax, fat and / or oily sub punch is melted before adding.

An expedient exit in a different direction design of the method according to the invention is thereby characterized in that the wax, fat and / or oil-like Substance before adding to the raw mass in an organic Solvent or dissolved or emulsified in water becomes. In this way, a thin, even at Generate a flowable solution at room temperature, which over Spray nozzles or atomizers evenly in the pre mixes raw mass can be introduced. This can  an even faster, better and more homogeneous kneading be achieved, especially when the total mixture relatively low in wax, fat and / or oil-like Substances.

This embodiment of the method according to the invention still has the advantage that screw extruder with Mixing lines, such as those used in plastics processing are known can be used. You can do this Mix, disperse, especially in one operation and shape.

However, the configuration according to claim 20 has the consequence that the mixture consisting of active ingredient, filler as well as wax, fat and / or oily substance must then be largely dried off.

Further expedient refinements of the method he give themselves from the subclaims 21-27.

Examples of use

The following are examples of the field of application of the substance according to the invention for application to the skin using exemplary recipes purifies. To use the substance as a cosmetic stick or mine (powder effect mine), the substance in the have the following composition: Figures in% by weight.  

Powder effect mine

To use the substance of the invention on the Pharmaceutical sector (here mosquito bite treatment pen) the substance can have the following composition:

Mosquito stick treatment stick

Furthermore, an example of composition will be given below the substance is shown, in which the substance as nourishing sunscreen is used.

Nourishing sunscreen in stick form

Manufacturing

1. First, the raw mass is mixed. Come to this several machine types and procedures in Be dress.

• a) Mixing can be done by kneaders, which usually two opposing (e.g. Have Z-shaped mixing arms). The powdery Components of the active ingredients as well as fillers are first introduced and stirred homogeneously. This stirring takes place at the same time  elevated temperature, preferably up to 100 ° C. Then the melted together wax, fat and / or oil-like substances poured in and into the powdery ingredient kneaded.
• This process can, if necessary be modified that the wax, oil and / or fat-like components in organic solution medium or dissolved or emulsified in water will. In this way, a thinner, produce a flowable solution even at room temperature, which then via spray nozzles or Zer dust evenly into the powdery premix can be introduced. This results in a faster, more homogeneous and better ver kneading, especially when the total mixture is poor of wax, fat and / or oil-like substances is. However, it is necessary here that Solution or emulsifying liquid before the mold drying the pen again (to a residual moisture of max. 1%).
• Alternatively, powder mixers can also be used be set as they are in the plastic processing manufacturing industry are common, especially then when you use solutions or emulsions. This has proven to be particularly advantageous the use of screw extruders with one plastic processing well-known mixing route. The use of screw extruders offers the advantage that in a single Mixed, dispersed and shaped operation can be.

2. Usually the mixing of the raw mass is complete a separate fine dispersing operation, Painting and pre-compression. This process advantageously takes place on a roller chair and can span several passages. Does that happen Further processing of the raw mass on suitable Screw extruders or piston presses included built, suitable screening devices, so this can Step may also be omitted.

3. Before shaping it is necessary to mix the mixture vent to the formation of cavities, air to avoid blowing, cracking or scratching in the product. Becomes granular or otherwise finely divided Material in screw extruders or vacuum pistons press shaped, so there is no additional work gear required. However, the material becomes one shaped piston presses, so it is required of the material before to air-free cylinders condense. This can preferably be done by means of ramming hammer or vacuum cartridge presses.

4. The shaping (here: pin or lead shape) takes place by extrusion into an "endless strand" a matrix of the desired width. Subsequently the strand is cut to pieces of the desired length cut. Pistons can be used for this presses of all kinds as well as plastic extruders. It can the material may be advantageous and / or parts of the machine in contact with the mass stop (max. 60 ° C) in order to close the pressures reduce and / or sufficient internal Ensure bond of mass.  

5. The moldings can then like pencils in Wood can be gripped or the lipsticks in rotation mechanics built in or like chalk in paper wrapped or like drop pins in a clip holder be accommodated.

How to use:

The substance according to the invention or from it The substance of the existing pen is similar like a piece of hard soap, which in connection with Water becomes very soft on the surface. The pen is in the Basically hard and firm, it is not ge in this form is suitable to ensure removal on human skin Afford.

Appropriately, the pen is therefore immediately in front Apply the pen to moisturize. This can be done under running water, under a water filled Small bowl or preferably by pressing in with a wet sponge, which is conveniently everywhere in a jar can be taken. By this Be Moisture will loosen the pen in a thin layer Layer from a few hundredths to a few tenths of a milli meters thick, in which the pen substance softens. In the area of this softened layer one can achieve a strong application with high edge sharpness.

In the case of decorative, i.e. H. cosmetic application the order can still be used for a while (a half to a minute) by wiping your finger or change with an applicator, d. H. distribute homogeneously or let it run thin towards the edge. Also there is the possibility with next to it to create smooth transitions in other colors.  

However, there is also the possibility that one for Application of the substance according to the invention not the pen but the skin itself before applying the substance damp. This is particularly advantageous if not a one-off order (mosquito bite action, eyeshadow), but a large area Order (e.g. sun protection or care for the whole Face, tint of large areas of the hair of the head or entire head hair). Hence can also a large-scale application of the invention Substance using any active ingredient produce.

The substance according to the invention ensures effort loose, soft application with complete avoidance of a oily, greasy sheen. It also stands out the substance of the invention by a high breaking and Temperature stability and excellent wiping strength from. All in all, the present offers Invention a profound development of the State of the art with regard to the skin load-bearing, solid substances.

Claims (26)

1. A substance in a solid state for application to the skin consisting of an active agent to produce a desired effect after application to the skin, a binding agent, and optionally fillers, characterized in that the binder is a wax and / or contains fat and / or oil-like substance or finally includes and the binder is water-soluble. 2. Substance according to claim 1, characterized, that the amount of wax, fat, or oil-like Substance 25-65 wt .-% based on the total weight of the ready-to-use substance. 3. substance according to claim 2, characterized, that the amount of wax, fat or oily Substance 28-42 wt .-% based on the total weight is. 4. Substance according to at least one of the previous ones claims, characterized, that the wax, fat or oil-containing substance too at least 3/10, preferably at least 6/10 from non-ionogenic, well water-soluble Material exists. 5. substance according to claim 4, characterized, that the water-soluble material made of poly ethylene glycol and / or polypropylene glycol  stands or at least one of the two Be has components. 6. substance according to claim 5, characterized, that polypropylene glycol and / or polyethylene glycol with a molecular weight between 300-6000 is used. 7. substance according to claim 4, characterized, that the easily water-soluble material synthetic, non-ionic W / O emulsifier, which is pH neutral as well as an HLB value equal to or greater than 13, has or consists exclusively of this. 8. substance according to claim 7, characterized, that as a synthetic non-ionic W / O emul gator with an ester of an organic acid Polyethylene glycol or a polyethylene oxide adduct with an organic acid or with a organic alcohol is provided. 9. Substance according to at least one of the previously claims,  characterized, that the wax, fat and / or oily substance at least 3/10 of fabrics with a Melting point is above 70 ° C. 10. Substance according to at least one of claims 1-8, characterized, that the wax, fat and / or oily substance at least 6/10 of fabrics with a Melting point is above 45 ° C. 11. Substance according to at least one of the previous ones claims, characterized, that colorants are provided as active ingredients. 12. substance according to claim 11, characterized, that the following substances alone as colorants or are provided in combination organic and / or inorganic cosmetic pig pearlescent agents, especially titanium dioxide coated mica, and / or metal powder,  especially aluminum, silver and gold powder. 13. Substance according to at least one of claims 1-10, characterized, that as active ingredient physiologically active substances are provided. 14. Substance according to claim 13, characterized, that the following as physiologically active agents Means provided alone or in combination are: Anesthetic or analgesic substances, preferably acetylsalicylic acid, anti phlogistic, cooling, decongestant preferably bisabolol, chamomile, menthol, or disinfectant, antibiotic substances, preferred wise aloe, iodine, sulfonamides, and caustic Substances, preferably salicylic acid, silver nitrate. 15. Substance according to at least one of claims 1-19,  characterized, that as an active ingredient skin protecting and / or skin nourishing substances are provided. 16. Composition according to claim 15, characterized, that as a skin protecting and / or skin care Substances following alone or in Combination are provided: UV filter or protective against dehydration Fabrics, preferably petroleum jelly, silicones, etc. and / or supple and softening Substances, preferably vegetable oils, in particular with essential fatty acids. 17. Substance according to at least one of the previous ones claims, characterized, that the substance to be applied to the skin Has a pencil or lead shape. 18. A method for producing the substance for wear according to at least one of the preceding claims, characterized in that

• a) the active ingredients and the fillers are mixed in advance, preferably in a kneading machine;
• b) then adding the wax, fat and / or oil-like substance;
• c) wherein at least process step b) takes place at an elevated temperature, preferably up to 100 ° C; and
• d) that the mixture is cooled to room temperature when the desired degree of homogeneity is reached.

19. The method according to claim 18, characterized, that the wax, fat and / or oily substance before the addition according to step b) in claim 18 is melted.   20. The method according to claim 18, characterized, that the wax, fat and / or oily substance before the addition according to process step b) Claim 18 in an organic solvent or is dissolved or emulsified in water. 21. The method according to claim 20, characterized, that the dissolved or emulsified wax, fat and / or oily substances in the front mixture can be injected or dusted. 22. The method according to claim 20, characterized, that the mixture consisting of active ingredient, filling substance as well as wax, fat or oily substance is finally dried. 23. The method according to at least one of claims 18-20, characterized, that mixing, dispersing and shaping using extruders, preferably Screw extruders are carried out.   24. Procedure according to at least one of the above outgoing claims characterized, that the raw mass is fine after the mixing process is dispersed, ground and pre-compacted. 25. Procedure according to at least one of the above claims, characterized, that the raw mass before shaping by com pression and / or ent is ventilated. 26. Procedure according to at least one of the above claims, characterized, that the raw mass before or during shaping is heated.