DE3879208D1 - Verfahren zur feststellung eines retinoblastoma-gen-defekts in tumoren, unter verwendung einer retinoblastoma-gen-probe. - Google Patents

Verfahren zur feststellung eines retinoblastoma-gen-defekts in tumoren, unter verwendung einer retinoblastoma-gen-probe.

Info

Publication number
DE3879208D1
DE3879208D1 DE8888906295T DE3879208T DE3879208D1 DE 3879208 D1 DE3879208 D1 DE 3879208D1 DE 8888906295 T DE8888906295 T DE 8888906295T DE 3879208 T DE3879208 T DE 3879208T DE 3879208 D1 DE3879208 D1 DE 3879208D1
Authority
DE
Germany
Prior art keywords
retinoblastoma gene
retinoblastoma
tumors
determining
defect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888906295T
Other languages
English (en)
Other versions
DE3879208T2 (de
Inventor
Yuen Kai T Fung
Ang Anne T
A Linn Murphree
William F Benedict
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canji Inc
Original Assignee
Research Development Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Development Foundation filed Critical Research Development Foundation
Application granted granted Critical
Publication of DE3879208D1 publication Critical patent/DE3879208D1/de
Publication of DE3879208T2 publication Critical patent/DE3879208T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Graft Or Block Polymers (AREA)
DE8888906295T 1987-05-29 1988-05-27 Verfahren zur feststellung eines retinoblastoma-gen-defekts in tumoren, unter verwendung einer retinoblastoma-gen-probe. Expired - Fee Related DE3879208T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878712646A GB8712646D0 (en) 1987-05-29 1987-05-29 Structural evidence
PCT/US1988/001809 WO1988009387A1 (en) 1987-05-29 1988-05-27 A method for detecting the predisposition to retinoblastoma and a method for detecting a retinoblastoma gene defect in tumors using a retinoblastoma gene probe

Publications (2)

Publication Number Publication Date
DE3879208D1 true DE3879208D1 (de) 1993-04-15
DE3879208T2 DE3879208T2 (de) 1993-07-22

Family

ID=10618110

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888906295T Expired - Fee Related DE3879208T2 (de) 1987-05-29 1988-05-27 Verfahren zur feststellung eines retinoblastoma-gen-defekts in tumoren, unter verwendung einer retinoblastoma-gen-probe.

Country Status (18)

Country Link
EP (2) EP0293266A3 (de)
JP (1) JPH04500751A (de)
KR (1) KR960002560B1 (de)
AT (1) ATE86673T1 (de)
AU (2) AU1983188A (de)
DE (1) DE3879208T2 (de)
DK (1) DK675088A (de)
ES (1) ES2054880T3 (de)
FI (1) FI895364A0 (de)
GB (1) GB8712646D0 (de)
GR (1) GR3007474T3 (de)
IE (1) IE62296B1 (de)
IL (1) IL86542A (de)
NO (1) NO301774B1 (de)
NZ (1) NZ224822A (de)
PT (1) PT87614B (de)
WO (1) WO1988009387A1 (de)
ZA (1) ZA883805B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853988A (en) * 1986-08-11 1998-12-29 Massachusetts Eye And Ear Infirmary Diagnosis of retinoblastoma
US7384735B1 (en) 1986-08-11 2008-06-10 Massachusetts Eye And Ear Infirmary Retinoblastoma nucleic acids
US7223842B1 (en) 1986-08-11 2007-05-29 Massachusetts Eye And Ear Infirmary Detection of proteins whose absence is associated with a neoplasm
CA1341576C (en) * 1986-08-11 2008-07-08 Thaddeus P. Dryja Diagnosis of retinoblastoma
EP0264274A3 (en) * 1986-10-14 1989-02-01 Canon Kabushiki Kaisha Optical recording medium
US5268267A (en) * 1987-08-21 1993-12-07 The General Hospital Corporation Method for diagnosing small cell carcinoma
WO1989006703A1 (en) * 1988-01-21 1989-07-27 Massachusetts Eye And Ear Infirmary Diagnosis of retinoblastoma
DE69032864T3 (de) * 1989-03-29 2013-01-31 The Johns Hopkins University Nachweis des Ausfalls des Wildtyps des p53-Gens
CA2060267A1 (en) * 1991-02-22 1992-08-23 Joe W. Gray Chromosome specific staining to detect genetic rearrangements
DK0667918T3 (da) 1991-11-14 2000-06-05 Dgi Inc Ikke-radioaktivt hybridiseringsassay og -sæt
CA2144768A1 (en) * 1992-10-01 1994-04-14 Stephen H. Friend Functional assay for tumor supressor genes
JPH06296489A (ja) * 1992-11-20 1994-10-25 Univ Texas Syst 網膜芽腫−関連タンパク質をコードする細胞性遺伝子
US5496731A (en) * 1993-03-25 1996-03-05 Xu; Hong-Ji Broad-spectrum tumor suppressor genes, gene products and methods for tumor suppressor gene therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341576C (en) * 1986-08-11 2008-07-08 Thaddeus P. Dryja Diagnosis of retinoblastoma

Also Published As

Publication number Publication date
DE3879208T2 (de) 1993-07-22
NO885712D0 (no) 1988-12-22
EP0293266A2 (de) 1988-11-30
GR3007474T3 (de) 1993-07-30
EP0364490A1 (de) 1990-04-25
IE62296B1 (en) 1995-01-25
ATE86673T1 (de) 1993-03-15
WO1988009387A1 (en) 1988-12-01
IL86542A (en) 1994-02-27
AU1983188A (en) 1988-12-21
PT87614B (pt) 1993-03-31
EP0364490B1 (de) 1993-03-10
NZ224822A (en) 1989-12-21
DK675088D0 (da) 1988-12-02
JPH04500751A (ja) 1992-02-13
IL86542A0 (en) 1988-11-15
IE881613L (en) 1988-11-29
KR890701763A (ko) 1989-12-21
EP0364490A4 (de) 1990-05-14
EP0293266A3 (de) 1990-04-11
ES2054880T3 (es) 1994-08-16
GB8712646D0 (en) 1987-07-01
NO885712L (no) 1988-12-22
PT87614A (pt) 1988-06-01
AU657143B2 (en) 1995-03-02
ZA883805B (en) 1990-11-28
NO301774B1 (no) 1997-12-08
DK675088A (da) 1988-12-02
AU2038292A (en) 1992-09-24
KR960002560B1 (ko) 1996-02-22
FI895364A0 (fi) 1989-11-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CANJI, INC., SAN DIEGO, CALIF., US

8328 Change in the person/name/address of the agent

Free format text: TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D., DIPL.-PHYS. DR.RER.NAT. RAUH, P., DIPL.-CHEM. DR.RER.NAT. HERMANN, G., DIPL.-PHYS. DR.RER.NAT. SCHMIDT, J., DIPL.-ING. JAENICHEN, H., DIPL.-BIOL. DR.RER.NAT. VON UEXKUELL-GUELDENBAND-MENZEL, A., DR.PHIL. (PH.D.) WEINBERGER, R., DIPL.-CHEM.UNIV. DR.RER.NAT. BUBLAK, W., DIPL.-CHEM. UNIV., PAT.-ANWAELTE TREMMEL, H., RECHTSANW., 81675 MUENCHEN

8339 Ceased/non-payment of the annual fee