DE3877337D1 - Verfahren zur mutagenese mittels oligonukleotid-gerichteter reparatur eines strandbruchs. - Google Patents

Verfahren zur mutagenese mittels oligonukleotid-gerichteter reparatur eines strandbruchs.

Info

Publication number
DE3877337D1
DE3877337D1 DE8888119339T DE3877337T DE3877337D1 DE 3877337 D1 DE3877337 D1 DE 3877337D1 DE 8888119339 T DE8888119339 T DE 8888119339T DE 3877337 T DE3877337 T DE 3877337T DE 3877337 D1 DE3877337 D1 DE 3877337D1
Authority
DE
Germany
Prior art keywords
mutagenese
oligonucleotide
directed repair
beach
break
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888119339T
Other languages
English (en)
Other versions
DE3877337T2 (de
Inventor
Wlodzimierz Mandecki
Mark Allan Hayden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE3877337D1 publication Critical patent/DE3877337D1/de
Publication of DE3877337T2 publication Critical patent/DE3877337T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/472—Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE19883877337 1987-12-11 1988-11-21 Verfahren zur mutagenese mittels oligonukleotid-gerichteter reparatur eines strandbruchs. Expired - Fee Related DE3877337T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13208987A 1987-12-11 1987-12-11

Publications (2)

Publication Number Publication Date
DE3877337D1 true DE3877337D1 (de) 1993-02-18
DE3877337T2 DE3877337T2 (de) 1993-08-19

Family

ID=22452419

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19883877337 Expired - Fee Related DE3877337T2 (de) 1987-12-11 1988-11-21 Verfahren zur mutagenese mittels oligonukleotid-gerichteter reparatur eines strandbruchs.

Country Status (3)

Country Link
EP (1) EP0319759B1 (de)
JP (1) JPH022348A (de)
DE (1) DE3877337T2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110079522A (zh) * 2019-05-14 2019-08-02 南方科技大学 一种单层二硫化钼的使用方法和dna的切割方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071743A (en) * 1989-10-27 1991-12-10 Her Majesty The Queen In Right Of Canada, As Represented By The National Research Council Of Canada Process for conducting site-directed mutagenesis
JPH04138770A (ja) * 1990-09-28 1992-05-13 Minolta Camera Co Ltd シェーディング補正方法
US5181379A (en) * 1990-11-15 1993-01-26 General Electric Company Gas turbine engine multi-hole film cooled combustor liner and method of manufacture
AU674137B2 (en) * 1992-01-30 1996-12-12 Genzyme Limited Chiral synthesis with modified enzymes
GB9906738D0 (en) * 1999-03-23 1999-05-19 Plant Bioscience Ltd Mutagenesis
US6335190B1 (en) * 2000-10-20 2002-01-01 New England Biolabs, Inc. Method for cloning and producing the BsmI restriction endonuclease in E. coli

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293652A (en) * 1979-05-25 1981-10-06 Cetus Corporation Method for synthesizing DNA sequentially
NZ208612A (en) * 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
DE3782365T2 (de) * 1986-07-08 1993-04-22 Abbott Lab Verfahren fuer die mutagenese durch eine oligonukleotidgeleitete reparatur eines strangbruchs.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110079522A (zh) * 2019-05-14 2019-08-02 南方科技大学 一种单层二硫化钼的使用方法和dna的切割方法

Also Published As

Publication number Publication date
JPH022348A (ja) 1990-01-08
EP0319759B1 (de) 1993-01-07
EP0319759A3 (en) 1990-05-23
DE3877337T2 (de) 1993-08-19
EP0319759A2 (de) 1989-06-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee