DE3869522D1 - Herstellung von (3s,4s)-(n-alpha-boc)-4-amino-5-cyclohexyl-3-hydroxypentansaeureethylester. - Google Patents

Herstellung von (3s,4s)-(n-alpha-boc)-4-amino-5-cyclohexyl-3-hydroxypentansaeureethylester.

Info

Publication number
DE3869522D1
DE3869522D1 DE8888306871T DE3869522T DE3869522D1 DE 3869522 D1 DE3869522 D1 DE 3869522D1 DE 8888306871 T DE8888306871 T DE 8888306871T DE 3869522 T DE3869522 T DE 3869522T DE 3869522 D1 DE3869522 D1 DE 3869522D1
Authority
DE
Germany
Prior art keywords
boc
cyclohexyl
alpha
amino
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888306871T
Other languages
English (en)
Inventor
Paul F Schuda
Prasun K Chakravarty
William J Greenlee
Philip Escola
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3869522D1 publication Critical patent/DE3869522D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86—Renin inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8888306871T 1987-07-31 1988-07-26 Herstellung von (3s,4s)-(n-alpha-boc)-4-amino-5-cyclohexyl-3-hydroxypentansaeureethylester. Expired - Fee Related DE3869522D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/080,943 US4788322A (en) 1987-07-31 1987-07-31 Process for preparing ACHPA

Publications (1)

Publication Number Publication Date
DE3869522D1 true DE3869522D1 (de) 1992-04-30

Family

ID=22160658

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888306871T Expired - Fee Related DE3869522D1 (de) 1987-07-31 1988-07-26 Herstellung von (3s,4s)-(n-alpha-boc)-4-amino-5-cyclohexyl-3-hydroxypentansaeureethylester.

Country Status (5)

Country Link
US (1) US4788322A (de)
EP (1) EP0306143B1 (de)
JP (1) JPS6442459A (de)
CA (1) CA1313881C (de)
DE (1) DE3869522D1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10333588A1 (de) * 2003-07-24 2005-02-17 Degussa Ag Verfahren zur Hydrierung aromatischer Verbindungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH589604A5 (de) * 1974-04-26 1977-07-15 Lonza Ag
CH588443A5 (de) * 1974-09-25 1977-06-15 Lonza Ag
US4296242A (en) * 1979-06-06 1981-10-20 Schering Corporation Process for the preparation of chiral 3-amino-2-hydroxypropionic acid and N-blocked derivatives thereof
US4487963A (en) * 1983-01-03 1984-12-11 Merck & Co., Inc. Enantioselective synthesis of 4-amino-3-hydroxy-2,4-(disubstituted)pentanoic acid
FR2565584B1 (fr) * 1984-06-06 1986-10-17 Sanofi Sa Derives d'acide heptanoique, leur procede de preparation ainsi que leur utilisation
FR2584399B1 (fr) * 1985-07-03 1989-11-03 Sanofi Sa Procede de synthese stereospecifique d'acides amino-4 hydroxy-3 carboxyliques
US4681972A (en) * 1986-09-16 1987-07-21 Warner-Lambert Company Separation of diastereomers

Also Published As

Publication number Publication date
EP0306143A1 (de) 1989-03-08
EP0306143B1 (de) 1992-03-25
JPH0587060B2 (de) 1993-12-15
CA1313881C (en) 1993-02-23
US4788322A (en) 1988-11-29
JPS6442459A (en) 1989-02-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee