DE3855693D1 - Geschützte Biotinderivate - Google Patents

Geschützte Biotinderivate

Info

Publication number
DE3855693D1
DE3855693D1 DE3855693T DE3855693T DE3855693D1 DE 3855693 D1 DE3855693 D1 DE 3855693D1 DE 3855693 T DE3855693 T DE 3855693T DE 3855693 T DE3855693 T DE 3855693T DE 3855693 D1 DE3855693 D1 DE 3855693D1
Authority
DE
Germany
Prior art keywords
processes
biotin derivatives
polynucleotides
protected biotin
biotinylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3855693T
Other languages
English (en)
Other versions
DE3855693T2 (de
Inventor
Michael Derek Edge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitto Denko Avecia Inc
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Application granted granted Critical
Publication of DE3855693D1 publication Critical patent/DE3855693D1/de
Publication of DE3855693T2 publication Critical patent/DE3855693T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
DE3855693T 1987-08-28 1988-08-26 Geschützte Biotinderivate Expired - Lifetime DE3855693T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878720394A GB8720394D0 (en) 1987-08-28 1987-08-28 Nucleotide probes

Publications (2)

Publication Number Publication Date
DE3855693D1 true DE3855693D1 (de) 1997-01-16
DE3855693T2 DE3855693T2 (de) 1997-04-03

Family

ID=10623008

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3855693T Expired - Lifetime DE3855693T2 (de) 1987-08-28 1988-08-26 Geschützte Biotinderivate

Country Status (15)

Country Link
US (1) US5247081A (de)
EP (1) EP0305201B1 (de)
JP (1) JP2746934B2 (de)
AT (1) ATE145917T1 (de)
AU (1) AU614764B2 (de)
CA (1) CA1340343C (de)
DE (1) DE3855693T2 (de)
DK (1) DK175706B1 (de)
FI (1) FI883931A (de)
GB (1) GB8720394D0 (de)
IL (1) IL87501A0 (de)
NO (1) NO883822L (de)
NZ (1) NZ225944A (de)
PT (1) PT88347B (de)
ZA (1) ZA886215B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262536A (en) * 1988-09-15 1993-11-16 E. I. Du Pont De Nemours And Company Reagents for the preparation of 5'-tagged oligonucleotides
US4997928A (en) * 1988-09-15 1991-03-05 E. I. Du Pont De Nemours And Company Fluorescent reagents for the preparation of 5'-tagged oligonucleotides
US4908453A (en) * 1989-01-23 1990-03-13 E. I. Du Pont De Nemours And Company Reagents for the preparation of 5'-biotinylated oligonucleotides
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
WO1991007087A1 (en) * 1989-11-13 1991-05-30 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
GB9009980D0 (en) * 1990-05-03 1990-06-27 Amersham Int Plc Phosphoramidite derivatives,their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides
EP0543930A1 (de) * 1990-08-17 1993-06-02 E.I. Du Pont De Nemours And Company Arthropodizide pyrazoline, pyrazolidine und hydrazine
AU2369895A (en) * 1994-04-29 1995-11-29 Perseptive Biosystems, Inc. Activated esters of 1-phenylpyrazolin-5-one for labelling amine-functionalized molecules
US5766550A (en) * 1995-03-15 1998-06-16 City Of Hope Disposable reagent storage and delivery cartridge
US20030180789A1 (en) * 1998-12-30 2003-09-25 Dale Roderic M.K. Arrays with modified oligonucleotide and polynucleotide compositions
US6087112A (en) * 1998-12-30 2000-07-11 Oligos Etc. Inc. Arrays with modified oligonucleotide and polynucleotide compositions
EP1136569A3 (de) * 2000-03-24 2004-01-28 Bayer Corporation Nukleinsäuresonden, die hoch-hydrophile nicht-nukleosidische Gruppen mit multiplen Markern enthalten und ihre Verwendungen
JP3841280B2 (ja) 2001-03-06 2006-11-01 株式会社リコー 電子写真感光体中間層用塗工液及びその製造方法、それを用いた電子写真感光体、電子写真装置及び電子写真装置用プロセスカートリッジ
WO2009092564A2 (en) * 2008-01-23 2009-07-30 Roche Diagnostics Gmbh Integrated instrument performing synthesis and amplification
US9206216B2 (en) 2010-04-21 2015-12-08 Pierce Biotechnology, Inc. Modified nucleotides methods and kits
US8536323B2 (en) 2010-04-21 2013-09-17 Pierce Biotechnology, Inc. Modified nucleotides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2489237A (en) * 1948-06-08 1949-11-22 Hoffmann La Roche 3, 4-(2'-keto-imidazolido)-2-omega-hydroxypentyl-thiophanes
JPS5745747B2 (de) * 1973-01-19 1982-09-29
US4247704A (en) * 1979-05-29 1981-01-27 Hoffmann-La Roche Inc. Hexahydro thieno imadazole intermediates for the synthesis of biotin
US4605735A (en) * 1983-02-14 1986-08-12 Wakunaga Seiyaku Kabushiki Kaisha Oligonucleotide derivatives
GB8509880D0 (en) * 1985-04-17 1985-05-22 Ici Plc Testing device
US4762779A (en) * 1985-06-13 1988-08-09 Amgen Inc. Compositions and methods for functionalizing nucleic acids
CH670644A5 (de) * 1986-12-18 1989-06-30 Lonza Ag
US4908453A (en) * 1989-01-23 1990-03-13 E. I. Du Pont De Nemours And Company Reagents for the preparation of 5'-biotinylated oligonucleotides

Also Published As

Publication number Publication date
IL87501A0 (en) 1989-01-31
NZ225944A (en) 1991-04-26
ATE145917T1 (de) 1996-12-15
US5247081A (en) 1993-09-21
GB8720394D0 (en) 1987-10-07
NO883822L (no) 1989-03-01
NO883822D0 (no) 1988-08-26
DK477488A (da) 1989-03-01
DK175706B1 (da) 2005-01-24
EP0305201A2 (de) 1989-03-01
EP0305201A3 (de) 1990-12-05
AU614764B2 (en) 1991-09-12
PT88347B (pt) 1995-05-04
FI883931A0 (fi) 1988-08-25
DE3855693T2 (de) 1997-04-03
PT88347A (pt) 1989-06-30
DK477488D0 (da) 1988-08-26
AU2113188A (en) 1989-03-02
JP2746934B2 (ja) 1998-05-06
FI883931A (fi) 1989-03-01
CA1340343C (en) 1999-01-26
EP0305201B1 (de) 1996-12-04
JPS6483093A (en) 1989-03-28
ZA886215B (en) 1990-03-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVECIA LTD., MANCHESTER, GB

8328 Change in the person/name/address of the agent

Free format text: HOFFMANN * EITLE, 81925 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: AVECIA BIOTECHNOLOGY, INC., MILFORD, MASS., US