DE3855577D1 - Retinoesäurerezeptor und Derivate davon, beide Substanzen codierende DNS und die Verwendung der Proteine und der DNS - Google Patents

Retinoesäurerezeptor und Derivate davon, beide Substanzen codierende DNS und die Verwendung der Proteine und der DNS

Info

Publication number
DE3855577D1
DE3855577D1 DE3855577T DE3855577T DE3855577D1 DE 3855577 D1 DE3855577 D1 DE 3855577D1 DE 3855577 T DE3855577 T DE 3855577T DE 3855577 T DE3855577 T DE 3855577T DE 3855577 D1 DE3855577 D1 DE 3855577D1
Authority
DE
Germany
Prior art keywords
dna
hap
retinoic acid
hepatoma
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3855577T
Other languages
English (en)
Other versions
DE3855577T2 (de
Inventor
Pierre Tiollais
Anne Dejean
De The Hugues Blaudin
Agnes Marchio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/134,130 external-priority patent/US5223606A/en
Priority claimed from US07/209,009 external-priority patent/US5149781A/en
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Publication of DE3855577D1 publication Critical patent/DE3855577D1/de
Application granted granted Critical
Publication of DE3855577T2 publication Critical patent/DE3855577T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE3855577T 1987-12-16 1988-12-16 Retinoesäurerezeptor und Derivate davon, beide Substanzen codierende DNS und die Verwendung der Proteine und der DNS Expired - Lifetime DE3855577T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13368787A 1987-12-16 1987-12-16
US07/134,130 US5223606A (en) 1987-12-16 1987-12-17 Steroid/thyroid hormone receptor-related protein inappropriately expressed in human hepatocellular carcinoma
US07/209,009 US5149781A (en) 1987-12-16 1988-06-20 Steroid/thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma
US27813688A 1988-11-30 1988-11-30

Publications (2)

Publication Number Publication Date
DE3855577D1 true DE3855577D1 (de) 1996-10-31
DE3855577T2 DE3855577T2 (de) 1997-04-17

Family

ID=27495052

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3855577T Expired - Lifetime DE3855577T2 (de) 1987-12-16 1988-12-16 Retinoesäurerezeptor und Derivate davon, beide Substanzen codierende DNS und die Verwendung der Proteine und der DNS

Country Status (8)

Country Link
US (3) US6531585B1 (de)
EP (1) EP0321362B1 (de)
AT (1) ATE143413T1 (de)
CA (1) CA1320161C (de)
DE (1) DE3855577T2 (de)
ES (1) ES2095207T3 (de)
GR (1) GR3021954T3 (de)
WO (1) WO1989005854A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4035889A (en) * 1988-06-16 1990-01-12 La Jolla Cancer Research Foundation Retinoic acid receptor
US6335159B1 (en) 1988-06-16 2002-01-01 The Burnham Institute Retinoic acid receptor ε(rarε)
US5260432A (en) * 1989-06-22 1993-11-09 Sloan-Kettering Institute For Cancer Research Human gamma retinoic acid receptor DNA
CA2020198A1 (en) * 1989-06-30 1990-12-31 Pierre Chambon Human and mouse retinoic acid receptors and genes encoding for them
FR2658204A1 (fr) * 1990-02-12 1991-08-16 Inst Nat Sante Rech Med Nouvelles compositions de cycline a humaine, sequence nucleotidique correspondante, et agents de detection ou de diagnostic de mutations hepatocellulaires induites par le virus hbv.
US5922596A (en) * 1990-12-10 1999-07-13 Bristol-Myers Squibb Co. Promoter of the retinoic acid receptor gene for directing gene expression
AU2001233114A1 (en) * 2000-02-04 2001-08-14 Aeomica, Inc. Methods and apparatus for predicting, confirming, and displaying functional information derived from genomic sequence
CA3114497A1 (en) 2013-01-18 2014-07-24 Cornell University Methods of treating diseases associated with high fat diet and vitamin a deficiency using retinoic acid receptor agonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4034114A (en) * 1976-09-15 1977-07-05 Yu Ruey J Treatment of skin keratoses with retinal
US4310546A (en) * 1978-07-31 1982-01-12 Johnson & Johnson Novel retinoids and their use in preventing carcinogenesis
US4323581A (en) * 1978-07-31 1982-04-06 Johnson & Johnson Method of treating carcinogenesis
US4385175A (en) * 1982-03-22 1983-05-24 Bristol-Myers Company Esters of retinoic acid and azetidinone derivatives
US4859609A (en) * 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5071773A (en) 1986-10-24 1991-12-10 The Salk Institute For Biological Studies Hormone receptor-related bioassays
US5571692A (en) * 1987-12-02 1996-11-05 The Salk Institute For Biological Studies Retinoic acid receptor α, vectors and cells comprising the same DNA encoding
US4981784A (en) * 1987-12-02 1991-01-01 The Salk Institute For Biological Studies Retinoic acid receptor method
US5171671A (en) * 1987-12-02 1992-12-15 The Salk Institute For Biological Studies Retinoic acid receptor composition

Also Published As

Publication number Publication date
DE3855577T2 (de) 1997-04-17
ATE143413T1 (de) 1996-10-15
US6531585B1 (en) 2003-03-11
EP0321362A1 (de) 1989-06-21
EP0321362B1 (de) 1996-09-25
ES2095207T3 (es) 1997-02-16
US7622266B2 (en) 2009-11-24
WO1989005854A1 (en) 1989-06-29
US20060189798A1 (en) 2006-08-24
CA1320161C (en) 1993-07-13
GR3021954T3 (en) 1997-03-31
US20030153740A1 (en) 2003-08-14

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