DE3850977T2 - Verfahren zur Herstellung von Azetidinonen. - Google Patents

Verfahren zur Herstellung von Azetidinonen.

Info

Publication number
DE3850977T2
DE3850977T2 DE3850977T DE3850977T DE3850977T2 DE 3850977 T2 DE3850977 T2 DE 3850977T2 DE 3850977 T DE3850977 T DE 3850977T DE 3850977 T DE3850977 T DE 3850977T DE 3850977 T2 DE3850977 T2 DE 3850977T2
Authority
DE
Germany
Prior art keywords
azetidinones
chem
production
penem
formulae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3850977T
Other languages
English (en)
Other versions
DE3850977D1 (de
Inventor
David William Heaton
Ian Main Cunningham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of DE3850977D1 publication Critical patent/DE3850977D1/de
Application granted granted Critical
Publication of DE3850977T2 publication Critical patent/DE3850977T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/04—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
DE3850977T 1987-01-30 1988-01-27 Verfahren zur Herstellung von Azetidinonen. Expired - Fee Related DE3850977T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878702139A GB8702139D0 (en) 1987-01-30 1987-01-30 Process

Publications (2)

Publication Number Publication Date
DE3850977D1 DE3850977D1 (de) 1994-09-15
DE3850977T2 true DE3850977T2 (de) 1994-12-15

Family

ID=10611502

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3850977T Expired - Fee Related DE3850977T2 (de) 1987-01-30 1988-01-27 Verfahren zur Herstellung von Azetidinonen.

Country Status (6)

Country Link
US (1) US4940788A (de)
EP (1) EP0276993B1 (de)
JP (1) JPS63246363A (de)
AT (1) ATE109771T1 (de)
DE (1) DE3850977T2 (de)
GB (1) GB8702139D0 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4876365A (en) * 1988-12-05 1989-10-24 Schering Corporation Intermediate compounds for preparing penems and carbapenems
KR100205767B1 (ko) * 1997-04-10 1999-07-01 이병언 아제티디논의 입체 선택적인 제조방법
EP2289888A3 (de) * 2000-06-30 2011-07-13 Seikagaku Corporation Epoxidcarboxylsäureamide, Azide und Aminoalkohole sowie Verfahren zur Herstellung von Alpha-Ketoamiden damit

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0181831B1 (de) * 1984-10-01 1993-08-25 Ciba-Geigy Ag Verfahren zur Herstellung von optisch aktiven Acyloxyazetidinonen
EP0221846A1 (de) * 1985-10-28 1987-05-13 Ciba-Geigy Ag Optisch aktive Acyloxyazetidinone

Also Published As

Publication number Publication date
JPS63246363A (ja) 1988-10-13
ATE109771T1 (de) 1994-08-15
DE3850977D1 (de) 1994-09-15
EP0276993A1 (de) 1988-08-03
GB8702139D0 (en) 1987-03-04
US4940788A (en) 1990-07-10
EP0276993B1 (de) 1994-08-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee