DE3690639T1 - - Google Patents

Info

Publication number
DE3690639T1
DE3690639T1 DE19863690639 DE3690639T DE3690639T1 DE 3690639 T1 DE3690639 T1 DE 3690639T1 DE 19863690639 DE19863690639 DE 19863690639 DE 3690639 T DE3690639 T DE 3690639T DE 3690639 T1 DE3690639 T1 DE 3690639T1
Authority
DE
Germany
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19863690639
Other languages
German (de)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of DE3690639T1 publication Critical patent/DE3690639T1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19863690639 1985-12-30 1986-11-24 Ceased DE3690639T1 (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/814,720 US4746659A (en) 1985-12-30 1985-12-30 Diastereomers of 10-alkyl-10-deazaminopterins and process for preparing the same

Publications (1)

Publication Number Publication Date
DE3690639T1 true DE3690639T1 (enExample) 1987-11-19

Family

ID=25215820

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19863690639 Ceased DE3690639T1 (enExample) 1985-12-30 1986-11-24

Country Status (6)

Country Link
US (1) US4746659A (enExample)
EP (1) EP0254726A1 (enExample)
JP (1) JPH089619B2 (enExample)
DE (1) DE3690639T1 (enExample)
GB (1) GB2192888B (enExample)
WO (1) WO1987004161A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684653A (en) * 1985-03-08 1987-08-04 The Trustees Of Princeton University Pyrido(2,3-d)pyrimidine derivatives
GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
US5030634A (en) * 1990-03-29 1991-07-09 Krumdieck Carlos L 10-deazaaminopterin: a new arthritis remittive drug
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
US5374726A (en) * 1992-03-03 1994-12-20 Degraw; Joseph I. Process for preparing 10-deazaaminopterins and 5,10-and 8,10-dideazaaminopterins from pteroic dicarboxylic acid diesters
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
AU4119993A (en) * 1992-04-29 1993-11-29 Sri International Heteroaroyl-10-deazaaminopterins for treatment of inflammation
US5260296A (en) * 1992-05-13 1993-11-09 Nair Madhavan G Thiophene substituted antitumor antifolates
US5550128A (en) * 1994-09-09 1996-08-27 Nair; Madhavan G. Enantiomers of gamma methylene 10-deaza aminopterin and process for preparing the same
US7541360B2 (en) * 2003-12-30 2009-06-02 Vasopharm Gmbh 4-amino-7,8-dihydropteridines, pharmaceutical compositions containing them and their use for the treatment of diseases which are caused by an increased nitric oxide level
CA2754007C (en) * 2009-01-24 2015-11-10 Aminopterin Llc Pharmaceutical composition comprising racemic aminopterin

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4433147A (en) * 1979-09-17 1984-02-21 Degraw Jr Joseph I Process for preparing 10-deazaminopterins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4433147A (en) * 1979-09-17 1984-02-21 Degraw Jr Joseph I Process for preparing 10-deazaminopterins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. Med. Chem. 14 (1971) S. 866-67 *

Also Published As

Publication number Publication date
JPS63502892A (ja) 1988-10-27
GB8718482D0 (en) 1987-09-09
WO1987004161A1 (en) 1987-07-16
GB2192888B (en) 1989-10-18
GB2192888A (en) 1988-01-27
EP0254726A1 (en) 1988-02-03
US4746659A (en) 1988-05-24
JPH089619B2 (ja) 1996-01-31

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection