DE3685786D1 - Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n-formylaminosaeure. - Google Patents

Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n-formylaminosaeure.

Info

Publication number
DE3685786D1
DE3685786D1 DE8686830247T DE3685786T DE3685786D1 DE 3685786 D1 DE3685786 D1 DE 3685786D1 DE 8686830247 T DE8686830247 T DE 8686830247T DE 3685786 T DE3685786 T DE 3685786T DE 3685786 D1 DE3685786 D1 DE 3685786D1
Authority
DE
Germany
Prior art keywords
formyl
ester
removal
peptide
formylamino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686830247T
Other languages
English (en)
Other versions
DE3685786T2 (de
Inventor
Goffredo Antonio Bolis
Giuseppe Cantarini
Col Marco Da
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lark SpA
Original Assignee
Lark SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lark SpA filed Critical Lark SpA
Application granted granted Critical
Publication of DE3685786D1 publication Critical patent/DE3685786D1/de
Publication of DE3685786T2 publication Critical patent/DE3685786T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/122—Hydrolysis with acids different from HF
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8686830247T 1985-09-30 1986-09-05 Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n-formylaminosaeure. Expired - Fee Related DE3685786T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22310/85A IT1190395B (it) 1985-09-30 1985-09-30 Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido

Publications (2)

Publication Number Publication Date
DE3685786D1 true DE3685786D1 (de) 1992-07-30
DE3685786T2 DE3685786T2 (de) 1993-01-21

Family

ID=11194494

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686830247T Expired - Fee Related DE3685786T2 (de) 1985-09-30 1986-09-05 Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n-formylaminosaeure.

Country Status (6)

Country Link
US (1) US4851563A (de)
EP (1) EP0214941B1 (de)
AT (1) ATE77627T1 (de)
CA (1) CA1290896C (de)
DE (1) DE3685786T2 (de)
IT (1) IT1190395B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8701035A (nl) * 1987-05-01 1988-12-01 Stamicarbon Werkwijze voor de bereiding van aspartylfenylalaninemethylester uit n-formylaspartylfenylalaninemethylester.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5823380B2 (ja) * 1974-12-05 1983-05-14 味の素株式会社 ホルミルキノ ダツリホウ
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
IT1194795B (it) * 1981-05-13 1988-09-28 Pierrel Spa Procedimento per la eliminazione del gruppo n-formile da peptidi n-formilati e da esteri di peptidi n-formilati
IT1175926B (it) * 1984-01-13 1987-08-12 Debi Derivati Biologici Procedimento per la preparazione dell'estere metilico di alfa-l-aspartil-l-fenilalanina
IT8422177A0 (it) * 1984-08-01 1984-08-01 Farchemia Spa Procedimento per la preparazione di esteri.

Also Published As

Publication number Publication date
IT1190395B (it) 1988-02-16
EP0214941B1 (de) 1992-06-24
ATE77627T1 (de) 1992-07-15
CA1290896C (en) 1991-10-15
IT8522310A0 (it) 1985-09-30
DE3685786T2 (de) 1993-01-21
US4851563A (en) 1989-07-25
EP0214941A3 (en) 1989-02-01
EP0214941A2 (de) 1987-03-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee