DE3684514D1 - Verwendung von penicillamin zur behandlung von immunmangelkrankheiten. - Google Patents
Verwendung von penicillamin zur behandlung von immunmangelkrankheiten.Info
- Publication number
- DE3684514D1 DE3684514D1 DE8686106646T DE3684514T DE3684514D1 DE 3684514 D1 DE3684514 D1 DE 3684514D1 DE 8686106646 T DE8686106646 T DE 8686106646T DE 3684514 T DE3684514 T DE 3684514T DE 3684514 D1 DE3684514 D1 DE 3684514D1
- Authority
- DE
- Germany
- Prior art keywords
- penicillamine
- treatment
- isomer
- htlv
- aids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229960001639 penicillamine Drugs 0.000 title abstract 5
- LJRDOKAZOAKLDU-UDXJMMFXSA-N (2s,3s,4r,5r,6r)-5-amino-2-(aminomethyl)-6-[(2r,3s,4r,5s)-5-[(1r,2r,3s,5r,6s)-3,5-diamino-2-[(2s,3r,4r,5s,6r)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol;sulfuric ac Chemical compound OS(O)(=O)=O.N[C@@H]1[C@@H](O)[C@H](O)[C@H](CN)O[C@@H]1O[C@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](N)C[C@@H](N)[C@@H]2O)O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)O[C@@H]1CO LJRDOKAZOAKLDU-UDXJMMFXSA-N 0.000 title abstract 3
- 208000026278 immune system disease Diseases 0.000 title 1
- 208000030507 AIDS Diseases 0.000 abstract 3
- VVNCNSJFMMFHPL-GSVOUGTGSA-N L-penicillamine Chemical compound CC(C)(S)[C@H](N)C(O)=O VVNCNSJFMMFHPL-GSVOUGTGSA-N 0.000 abstract 3
- 241000700605 Viruses Species 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- VVNCNSJFMMFHPL-VKHMYHEASA-N D-penicillamine Chemical compound CC(C)(S)[C@@H](N)C(O)=O VVNCNSJFMMFHPL-VKHMYHEASA-N 0.000 abstract 1
- 208000029462 Immunodeficiency disease Diseases 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 231100001231 less toxic Toxicity 0.000 abstract 1
- VVNCNSJFMMFHPL-UHFFFAOYSA-N penicillamine Chemical compound CC(C)(S)C(N)C(O)=O VVNCNSJFMMFHPL-UHFFFAOYSA-N 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE8686106646T DE3684514D1 (de) | 1985-06-08 | 1986-05-15 | Verwendung von penicillamin zur behandlung von immunmangelkrankheiten. |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3520624 | 1985-06-08 | ||
| DE8686106646T DE3684514D1 (de) | 1985-06-08 | 1986-05-15 | Verwendung von penicillamin zur behandlung von immunmangelkrankheiten. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3684514D1 true DE3684514D1 (de) | 1992-04-30 |
Family
ID=6272806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8686106646T Expired - Lifetime DE3684514D1 (de) | 1985-06-08 | 1986-05-15 | Verwendung von penicillamin zur behandlung von immunmangelkrankheiten. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4847297A (enExample) |
| EP (1) | EP0204989B1 (enExample) |
| JP (1) | JPS61286325A (enExample) |
| AT (1) | ATE73995T1 (enExample) |
| AU (1) | AU584551B2 (enExample) |
| CA (1) | CA1283859C (enExample) |
| DE (1) | DE3684514D1 (enExample) |
| ZA (1) | ZA864263B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192788A (en) * | 1988-05-23 | 1993-03-09 | Georgia State University Foundation, Inc. | Porphyrin antiviral compositions |
| US5109016A (en) * | 1988-05-23 | 1992-04-28 | Georgia State University Foundation, Inc. | Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions |
| US5061700A (en) * | 1989-11-16 | 1991-10-29 | Gordon Jay Dow | Glyceryl acetate ointment vehicles |
| US5554655A (en) * | 1991-09-30 | 1996-09-10 | Jess G. Thoene | Method of treating HIV infection |
| PT100914A (pt) * | 1991-09-30 | 1993-10-29 | Jess G Thoene | Uso de compostos capazes de sofrer uma permuta mista com dissulfureto, com uma ligacao dissulfureto, no tratamento de infeccao por hiv |
| US6764693B1 (en) | 1992-12-11 | 2004-07-20 | Amaox, Ltd. | Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants |
| EP0789565A4 (en) * | 1993-10-15 | 1999-03-24 | Jess G Thoene | PREVENTION OF HIV INFECTION |
| US5725870A (en) * | 1993-10-15 | 1998-03-10 | Thoene; Jess G. | Methods, composites and articles for contraception |
| US6541517B1 (en) | 1999-09-03 | 2003-04-01 | Donald M. Murphy | Treatment of skin disorders |
| US6117904A (en) * | 1999-09-03 | 2000-09-12 | Murphy; Donald M. | Treatment of pruritus |
| US20070134277A1 (en) * | 2005-12-09 | 2007-06-14 | Children's Medical Center Corporation | Pharmaceutical formulation for sulfur-containing drugs in liquid dosage forms |
| US20100166833A1 (en) * | 2007-05-07 | 2010-07-01 | Technion Research & Development Foundation Ltd. | Compositions, articles and methods for preventing or reducing tobacco-associated damage |
| US20190282519A1 (en) * | 2018-03-19 | 2019-09-19 | Cronus Research Labs Private Limited | Pencillamine oral composition |
| JP2024059517A (ja) * | 2022-10-18 | 2024-05-01 | 国立研究開発法人医薬基盤・健康・栄養研究所 | ウイルス量を調整する方法、ウイルス感染症を治療又は予防する方法、ウイルス量を推定する方法、及び対象のウイルス感染症の予後を予測する方法、並びにこれらの方法のための組成物及びシステム |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB585413A (en) * | 1944-06-19 | 1947-02-06 | Wellcome Found | Improved method for the resolution of penicillamine |
| FR2182892B1 (enExample) * | 1972-03-25 | 1976-11-05 | Degussa | |
| CH588887A5 (enExample) * | 1974-07-19 | 1977-06-15 | Battelle Memorial Institute | |
| US4487780A (en) * | 1979-09-18 | 1984-12-11 | Scheinberg Israel H | Method of treatment of rheumatoid arthritis |
-
1986
- 1986-05-15 EP EP86106646A patent/EP0204989B1/de not_active Expired - Lifetime
- 1986-05-15 AT AT86106646T patent/ATE73995T1/de active
- 1986-05-15 DE DE8686106646T patent/DE3684514D1/de not_active Expired - Lifetime
- 1986-06-05 JP JP61129362A patent/JPS61286325A/ja active Granted
- 1986-06-06 CA CA000511011A patent/CA1283859C/en not_active Expired - Lifetime
- 1986-06-06 ZA ZA864263A patent/ZA864263B/xx unknown
- 1986-06-06 AU AU58440/86A patent/AU584551B2/en not_active Ceased
-
1988
- 1988-03-16 US US07/170,638 patent/US4847297A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE73995T1 (de) | 1992-04-15 |
| EP0204989B1 (de) | 1992-03-25 |
| ZA864263B (en) | 1987-02-25 |
| CA1283859C (en) | 1991-05-07 |
| AU5844086A (en) | 1986-12-11 |
| EP0204989A2 (de) | 1986-12-17 |
| JPS61286325A (ja) | 1986-12-16 |
| AU584551B2 (en) | 1989-05-25 |
| JPH0380772B2 (enExample) | 1991-12-26 |
| EP0204989A3 (en) | 1989-12-20 |
| US4847297A (en) | 1989-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: ASTA MEDICA AG, O-8020 DRESDEN, DE |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: CHANDRA, PRAKASH, PROF. DR.PHIL.NAT., 60489 FRANKF |
|
| 8339 | Ceased/non-payment of the annual fee |