DE3683844D1 - Impfstoff des klebsiella kapsulpolysaccharids. - Google Patents
Impfstoff des klebsiella kapsulpolysaccharids.Info
- Publication number
- DE3683844D1 DE3683844D1 DE8686302311T DE3683844T DE3683844D1 DE 3683844 D1 DE3683844 D1 DE 3683844D1 DE 8686302311 T DE8686302311 T DE 8686302311T DE 3683844 T DE3683844 T DE 3683844T DE 3683844 D1 DE3683844 D1 DE 3683844D1
- Authority
- DE
- Germany
- Prior art keywords
- polysaccharides
- capsular
- klebsiella
- serotype
- purified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000588748 Klebsiella Species 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 150000004676 glycans Chemical class 0.000 abstract 6
- 229920001282 polysaccharide Polymers 0.000 abstract 6
- 239000005017 polysaccharide Substances 0.000 abstract 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 241000700198 Cavia Species 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- 241000283973 Oryctolagus cuniculus Species 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 239000002158 endotoxin Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 229920006008 lipopolysaccharide Polymers 0.000 abstract 1
- 229940031348 multivalent vaccine Drugs 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001698 pyrogenic effect Effects 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 238000005199 ultracentrifugation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0266—Klebsiella
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP86302311A EP0238739B1 (en) | 1986-03-27 | 1986-03-27 | Klebsiella capsular polysaccharide vaccine |
| ZA862478A ZA862478B (enExample) | 1986-03-27 | 1986-04-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3683844D1 true DE3683844D1 (de) | 1992-03-19 |
Family
ID=26103944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8686302311T Expired - Lifetime DE3683844D1 (de) | 1986-03-27 | 1986-03-27 | Impfstoff des klebsiella kapsulpolysaccharids. |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0238739B1 (enExample) |
| AT (1) | ATE72401T1 (enExample) |
| DE (1) | DE3683844D1 (enExample) |
| ZA (1) | ZA862478B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10194979A (ja) * | 1997-01-07 | 1998-07-28 | Teika Corp | イムノグロブリンe抗体産生抑制剤 |
| CA2316975C (en) † | 1997-12-23 | 2009-03-24 | North American Vaccine, Inc. | Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugate vaccines |
| CA2636983A1 (en) * | 2006-01-13 | 2007-07-26 | Baxter International Inc. | Method for purifying polysaccharides |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2510606A1 (fr) * | 1981-07-30 | 1983-02-04 | Berri Balzac | Procede d'obtention de polyosides capsulaires, polyosides capsulaires ainsi obtenus et leur application a la preparation de vaccins |
-
1986
- 1986-03-27 EP EP86302311A patent/EP0238739B1/en not_active Expired - Lifetime
- 1986-03-27 AT AT86302311T patent/ATE72401T1/de not_active IP Right Cessation
- 1986-03-27 DE DE8686302311T patent/DE3683844D1/de not_active Expired - Lifetime
- 1986-04-03 ZA ZA862478A patent/ZA862478B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE72401T1 (de) | 1992-02-15 |
| EP0238739B1 (en) | 1992-02-05 |
| EP0238739A1 (en) | 1987-09-30 |
| ZA862478B (enExample) | 1986-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |