DE3682723D1 - Strahlungssensibilisator. - Google Patents
Strahlungssensibilisator.Info
- Publication number
- DE3682723D1 DE3682723D1 DE8686111172T DE3682723T DE3682723D1 DE 3682723 D1 DE3682723 D1 DE 3682723D1 DE 8686111172 T DE8686111172 T DE 8686111172T DE 3682723 T DE3682723 T DE 3682723T DE 3682723 D1 DE3682723 D1 DE 3682723D1
- Authority
- DE
- Germany
- Prior art keywords
- radiation sensitizer
- sensitizer
- radiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002534 radiation-sensitizing agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60178549A JPH0720864B2 (ja) | 1985-08-15 | 1985-08-15 | 放射線増感剤 |
JP27797585A JPH0723308B2 (ja) | 1985-12-12 | 1985-12-12 | 放射線増感剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3682723D1 true DE3682723D1 (de) | 1992-01-16 |
Family
ID=26498698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686111172T Expired - Lifetime DE3682723D1 (de) | 1985-08-15 | 1986-08-12 | Strahlungssensibilisator. |
Country Status (3)
Country | Link |
---|---|
US (1) | US4820844A (de) |
EP (1) | EP0212558B1 (de) |
DE (1) | DE3682723D1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1329206C (en) * | 1987-06-10 | 1994-05-03 | Tsutomu Kagiya | Fluorine-containing nitroazole derivatives and radiosensitizer comprising the same |
US5304654A (en) * | 1987-06-10 | 1994-04-19 | Yasunori Nishijima | Fluorine-containing nitroimidazole compounds |
JPH0819111B2 (ja) * | 1987-10-22 | 1996-02-28 | ポーラ化成工業株式会社 | 2―ニトロイミダゾール誘導体及びこれを有効成分とする放射線増感剤 |
US6159143A (en) * | 1998-06-17 | 2000-12-12 | Scimed Life Systems, Inc. | Method and device for delivery of therapeutic agents in conjunction with isotope seed placement |
EP1545705A4 (de) | 2000-11-16 | 2010-04-28 | Microspherix Llc | Flexibler und/oder elastischer brachytherapie-seed oder strang |
US6514193B2 (en) | 2000-11-16 | 2003-02-04 | Microspherix Llc | Method of administering a therapeutically active substance |
US8187159B2 (en) | 2005-07-22 | 2012-05-29 | Biocompatibles, UK | Therapeutic member including a rail used in brachytherapy and other radiation therapy |
US7736293B2 (en) * | 2005-07-22 | 2010-06-15 | Biocompatibles Uk Limited | Implants for use in brachytherapy and other radiation therapy that resist migration and rotation |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4371540A (en) * | 1979-09-14 | 1983-02-01 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nitroimidazoles of low toxicity and high activity as radiosensitizers of hypoxic tumor cells |
US4462992A (en) * | 1982-02-08 | 1984-07-31 | Research Corporation | Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof |
-
1986
- 1986-08-12 DE DE8686111172T patent/DE3682723D1/de not_active Expired - Lifetime
- 1986-08-12 US US06/896,135 patent/US4820844A/en not_active Expired - Lifetime
- 1986-08-12 EP EP86111172A patent/EP0212558B1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0212558A2 (de) | 1987-03-04 |
US4820844A (en) | 1989-04-11 |
EP0212558A3 (en) | 1988-06-01 |
EP0212558B1 (de) | 1991-12-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |