DE3682723D1 - Strahlungssensibilisator. - Google Patents

Strahlungssensibilisator.

Info

Publication number
DE3682723D1
DE3682723D1 DE8686111172T DE3682723T DE3682723D1 DE 3682723 D1 DE3682723 D1 DE 3682723D1 DE 8686111172 T DE8686111172 T DE 8686111172T DE 3682723 T DE3682723 T DE 3682723T DE 3682723 D1 DE3682723 D1 DE 3682723D1
Authority
DE
Germany
Prior art keywords
radiation sensitizer
sensitizer
radiation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686111172T
Other languages
English (en)
Inventor
Tsutomu Kagiya
Motonobu Minagawa
Yutaka Nakahara
Ryoji F-C- Heim Freuden Kimura
Tsuneo Tsubakimoto
Ryochi Oshiumi
Daigoishida-Danchi Sakano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adeka Corp
Kyoto University NUC
Original Assignee
Asahi Denka Kogyo KK
Kyoto University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP60178549A external-priority patent/JPH0720864B2/ja
Priority claimed from JP27797585A external-priority patent/JPH0723308B2/ja
Application filed by Asahi Denka Kogyo KK, Kyoto University NUC filed Critical Asahi Denka Kogyo KK
Application granted granted Critical
Publication of DE3682723D1 publication Critical patent/DE3682723D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8686111172T 1985-08-15 1986-08-12 Strahlungssensibilisator. Expired - Lifetime DE3682723D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP60178549A JPH0720864B2 (ja) 1985-08-15 1985-08-15 放射線増感剤
JP27797585A JPH0723308B2 (ja) 1985-12-12 1985-12-12 放射線増感剤

Publications (1)

Publication Number Publication Date
DE3682723D1 true DE3682723D1 (de) 1992-01-16

Family

ID=26498698

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686111172T Expired - Lifetime DE3682723D1 (de) 1985-08-15 1986-08-12 Strahlungssensibilisator.

Country Status (3)

Country Link
US (1) US4820844A (de)
EP (1) EP0212558B1 (de)
DE (1) DE3682723D1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1329206C (en) * 1987-06-10 1994-05-03 Tsutomu Kagiya Fluorine-containing nitroazole derivatives and radiosensitizer comprising the same
US5304654A (en) * 1987-06-10 1994-04-19 Yasunori Nishijima Fluorine-containing nitroimidazole compounds
JPH0819111B2 (ja) * 1987-10-22 1996-02-28 ポーラ化成工業株式会社 ２―ニトロイミダゾール誘導体及びこれを有効成分とする放射線増感剤
US6159143A (en) * 1998-06-17 2000-12-12 Scimed Life Systems, Inc. Method and device for delivery of therapeutic agents in conjunction with isotope seed placement
EP1545705A4 (de) 2000-11-16 2010-04-28 Microspherix Llc Flexibler und/oder elastischer brachytherapie-seed oder strang
US6514193B2 (en) 2000-11-16 2003-02-04 Microspherix Llc Method of administering a therapeutically active substance
US8187159B2 (en) 2005-07-22 2012-05-29 Biocompatibles, UK Therapeutic member including a rail used in brachytherapy and other radiation therapy
US7736293B2 (en) * 2005-07-22 2010-06-15 Biocompatibles Uk Limited Implants for use in brachytherapy and other radiation therapy that resist migration and rotation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371540A (en) * 1979-09-14 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Nitroimidazoles of low toxicity and high activity as radiosensitizers of hypoxic tumor cells
US4462992A (en) * 1982-02-08 1984-07-31 Research Corporation Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof

Also Published As

Publication number Publication date
EP0212558A2 (de) 1987-03-04
US4820844A (en) 1989-04-11
EP0212558A3 (en) 1988-06-01
EP0212558B1 (de) 1991-12-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition