DE3680740D1 - Die differenzierung maligner zellen bewirkende seco-sterol-verbindungen. - Google Patents

Die differenzierung maligner zellen bewirkende seco-sterol-verbindungen.

Info

Publication number
DE3680740D1
DE3680740D1 DE8686903000T DE3680740T DE3680740D1 DE 3680740 D1 DE3680740 D1 DE 3680740D1 DE 8686903000 T DE8686903000 T DE 8686903000T DE 3680740 T DE3680740 T DE 3680740T DE 3680740 D1 DE3680740 D1 DE 3680740D1
Authority
DE
Germany
Prior art keywords
maligner
seco
differentiation
cell
effective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686903000T
Other languages
English (en)
Inventor
Hector F Deluca
Heinrich K Schnoes
Wan F Lau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Application granted granted Critical
Publication of DE3680740D1 publication Critical patent/DE3680740D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE8686903000T 1985-04-23 1986-04-21 Die differenzierung maligner zellen bewirkende seco-sterol-verbindungen. Expired - Lifetime DE3680740D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72655385A 1985-04-23 1985-04-23
US72649685A 1985-04-23 1985-04-23
PCT/US1986/000833 WO1986006255A1 (en) 1985-04-23 1986-04-21 Seco-sterol compounds effective in inducing the differentiation of malignant cells

Publications (1)

Publication Number Publication Date
DE3680740D1 true DE3680740D1 (de) 1991-09-12

Family

ID=27111330

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686903000T Expired - Lifetime DE3680740D1 (de) 1985-04-23 1986-04-21 Die differenzierung maligner zellen bewirkende seco-sterol-verbindungen.

Country Status (6)

Country Link
EP (1) EP0218714B1 (de)
AU (2) AU599912B2 (de)
DE (1) DE3680740D1 (de)
GB (2) GB2185017B (de)
IE (1) IE58473B1 (de)
WO (1) WO1986006255A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0443021A1 (de) * 1989-09-11 1991-08-28 Wisconsin Alumni Research Foundation Verwendung von vitamin d-verbindungen zur hemmung der aids-viren-vermehrung
CA2062520C (en) * 1991-03-11 1998-08-11 Hector F. Deluca Synthesis of 1-alpha-hydroxy-secosterol compounds
WO2001090061A1 (fr) * 2000-05-23 2001-11-29 Chugai Seiyaku Kabushiki Kaisha Derives de 5, 6-trans-2-alkylevitamine d
CN1308303C (zh) * 2001-12-13 2007-04-04 威斯康星校友研究基金会 (20S)－1α－羟基－2－亚甲基－19－去甲－双高孕钙化醇及其应用
US6627622B2 (en) 2002-02-18 2003-09-30 Wisconsin Alumni Research Foundation (20S)-1α-hydroxy-2-methylene-19-nor-bishomopregnacalciferol and its uses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57149224A (en) * 1981-03-13 1982-09-14 Chugai Pharmaceut Co Ltd Tumor-suppressing agent
US4588716A (en) * 1984-05-04 1986-05-13 Wisconsin Alumni Research Foundation Method for treating metabolic bone disease in mammals
DE3577552D1 (de) * 1984-11-27 1990-06-13 Chugai Pharmaceutical Co Ltd Vitamin d-derivate und verfahren zu deren herstellung.

Also Published As

Publication number Publication date
GB2212803B (en) 1989-12-06
IE861044L (en) 1986-10-23
GB2185017B (en) 1989-11-29
GB8817383D0 (en) 1988-08-24
GB2185017A (en) 1987-07-08
AU5772786A (en) 1986-11-18
AU4537389A (en) 1990-03-08
EP0218714A1 (de) 1987-04-22
EP0218714A4 (de) 1987-08-12
AU599912B2 (en) 1990-08-02
GB8629783D0 (en) 1987-01-21
EP0218714B1 (de) 1991-08-07
AU616323B2 (en) 1991-10-24
IE58473B1 (en) 1993-09-22
WO1986006255A1 (en) 1986-11-06
GB2212803A (en) 1989-08-02

Similar Documents

Publication Publication Date Title
IT8622281A0 (it) Metodi per la preparazione di medicazioni.
ES557723A0 (es) Procedimiento para la produccion de tiazoles
IT1190018B (it) Procedimento per la produzione di beta-allumina
IT1189589B (it) Procedimento per l'esercizio di un estrusore
DE3677337D1 (de) Matrize.
ES552585A0 (es) Procedimiento para la union quimica de compuestos de moldeo.
ES556313A0 (es) Procedimiento para la produccion de gamma-butirolactona.
IT8519847A0 (it) Processo per la preparazione di fluorossi-alo-composti.
DK477186A (da) Indolobenzodiazepinforbindelser
DK282687A (da) Ekstrusionsmatrice
IT8620726A1 (it) Stampo
DK256886D0 (da) Granuleringsapparat
IT1201435B (it) Procedimento per la produzione di alchil trifluracetati
DE3680740D1 (de) Die differenzierung maligner zellen bewirkende seco-sterol-verbindungen.
DK429986A (da) 2-oxa-isocephemforbindelser
IT8622149A0 (it) Procedimento per la produzione di gnocchi.
DE3666434D1 (de) Oxodiazine compounds
DK135886A (da) Cyanoalkanimidamidoforbindelser
AT386772B (de) Strangpressmatrize
DE3581505D1 (de) Differenzierung menschlicher zellen.
FI863883A0 (fi) Anordning foer tillslutning av flaskhals.
IT1183535B (it) Procedimento per la produzione di isobutilene
BR8605955A (pt) Compostos de pirazolina
RO93100A2 (ro) Stanta
ES555439A0 (es) Procedimiento para la fabricacion de compuestos hidroximetilcefem

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee