DE3614292C1 - Holder for unframed biological mitral valve implant - Google Patents

Holder for unframed biological mitral valve implant

Info

Publication number
DE3614292C1
DE3614292C1 DE3614292A DE3614292A DE3614292C1 DE 3614292 C1 DE3614292 C1 DE 3614292C1 DE 3614292 A DE3614292 A DE 3614292A DE 3614292 A DE3614292 A DE 3614292A DE 3614292 C1 DE3614292 C1 DE 3614292C1
Authority
DE
Germany
Prior art keywords
holder
mitral valve
unframed
biological
characterized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3614292A
Other languages
German (de)
Inventor
Alexander Prof Dr Bernhard
Hans-Hinrich Dr Sievers
Mehrdad Dr Mahmoodi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BERNHARD ALEXANDER PROF DR 2300 KIEL DE
Original Assignee
BERNHARD ALEXANDER PROF DR 2300 KIEL DE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BERNHARD ALEXANDER PROF DR 2300 KIEL DE filed Critical BERNHARD ALEXANDER PROF DR 2300 KIEL DE
Priority to DE3614292A priority Critical patent/DE3614292C1/en
Application granted granted Critical
Publication of DE3614292C1 publication Critical patent/DE3614292C1/en
Application status is Expired legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2442Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2454Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
    • A61F2/2457Chordae tendineae prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/20Holders specially adapted for surgical or diagnostic appliances or instruments

Abstract

Holder for unframed biological mitral valve apparatus for the preparation, preservation, storage, fitment and/or sewing-in thereof, which comprises a holding ring designed in the form of the mitral valve ring and two plate elements each fastened on the holding ring by a respective connecting element made of a flexible material, the distance of the plate elements from the holding ring corresponding to the distance between the mitral valve ring and the papillary muscles of the mitral valve apparatus to be implanted.

Description

Die Erfindung betrifft einen Halter für ein ungerahmtes biologisches Mitralklappenimplantat. The invention relates to a holder for a unframed biological Mitralklappenimplantat.

Der Ersatz der menschlichen Mitralklappe durch biologi sche, vom Schwein gewonnene Mitralklappenimplantate ist seit längerem bekannt. The replacement of the human mitral valve through biological specific, derived from pigs Mitralklappenimplantate has long been known. Die dabei verwendeten Mitral klappenimplantate sind in einem mit dem Klappenimplantat zu implantierenden Rahmen versehen. The mitral valve implants used in this case are provided in a valve implant to be implanted with the frame. Die Verwendung derartiger gerahmter biologischer Implantate haben jedoch den Nachteil, Raum zu benötigen und so zu einer Stenose zu führen. The use of such framed biological implants have the need for space and thus lead to a stenosis disadvantage. Weiter wird die normale Bewegung behindert, was zu Thrombosen, Verkalkung oder Degenera tionserscheinungen führen kann. Next the normal movement is hindered, which can lead to thrombosis, calcification or Degenera tion phenomena. Nachteilig ist bei derartigen gerahmten biologischen Klappenimplantaten weiter, daß andere als bei dem normalen Herz der ven trikulare Muskel das funktionale Öffnen und Schließen der Klappe nicht unterstützt. The disadvantage with such framed biological valve implants on that other than in the normal heart muscle of ven trikulare not support the functional opening and closing the door.

Es ist daher wünschenswert, komplette biologische, ungerahmte, vorzugsweise vom Schwein gewonnene Mitral klappenimplantate mit Sehnenfäden und Papillarmuskel kopf zu implantieren. It is therefore desirable to complete biological, unframed, preferably derived from pig mitral fold implants to implant head with chordae and papillary muscle. Erste entsprechende Versuche waren bereits erfolgreich. First such attempts had been successful.

Die Präparation, Konservierung, Aufbewahrung, Einpas sung und Einnähung dieser Mitralklappenimplantate in die linke Herzkammer ohne besondere Vorrichtungen hat sich als schwierig erwiesen. The preparation, preservation, storage, measurement and insal Einnähung this Mitralklappenimplantate in the left ventricle without special devices has proven difficult.

Der Erfindung liegt die Aufgabe zugrunde, einen Halter für ein ungerahmtes biologisches Mitralklappenimplantat zu deren Präparation, Konservierung, Aufbewahrung, Einpassung und/oder Einnähung zu schaffen. The invention has for its object to provide a holder for a unframed biological Mitralklappenimplantat for their preparation, preservation, storage, fitting and / or Einnähung.

Erfindungsgemäß wird diese Aufgabe gelöst durch einen in Form eines menschlichen Mitralklappenringes ausge bildeten Haltering und zwei mittels jeweils einem aus einem biegsamen Material bestehenden Verbindungselemen ten an dem Haltering befestigte Plattenelemente, wobei der Abstand der Plattenelemente von dem Haltering dem Abstand zwischen dem Mitralklappenring und den Papillar muskeln des zu implantierenden Mitralklappenimplantats entspricht. According to the invention this object is achieved through a hollow in the form of a human mitral valve annulus formed retaining ring and two by means of each one consisting of a flexible material Verbindungselemen th fixed to the holding ring plate members, the distance of the plate elements of the retaining ring to the distance between the mitral valve annulus and the papillary muscles of the to be implanted Mitralklappenimplantats corresponds.

Vorzugsweise ist vorgesehen, daß der Haltering mit einer zur Aufnahme eines Klemmrings dienenden Innennut versehen ist, wobei der Haltering aus einem Kunststoff besteht. It is preferably provided that the retaining ring is provided with a serving to receive a clamping ring inner groove, wherein the retaining ring consists of a plastic.

Die Verbindungselemente bestehen vorzugsweise aus Me talldraht. The connecting elements are preferably talldraht from Me.

Als Material für die Plattenelemente kommt Kunststoff in Betracht. As the material of the plate elements plastic comes into consideration. Dabei sind vorzugsweise seitliche, eine Markierung des Vernähungsortes der Papillarmuskeln ermöglichende Ausnehmungen vorgesehen, durch die bei spielsweise ein Markierungsstich gesetzt werden kann. In this case, a marker of the papillary muscles Vernähungsortes enabling lateral recesses are preferably provided, a marker can be set by the stitch at play. Bei einer besonders bevorzugten Ausgestaltung bestehen die Plattenelemente jedoch aus einem Teflonfilz, wobei der Teflonfilz mit den bei der Präparation auf diesen aufgenähten Papillarmuskeln in der Herzkammer vernäht wird und in dieser verbleibt. In a particularly preferred embodiment, however, the plate members are made of a Teflon felt, the Teflon felt is sutured with the in the preparation of these sewn papillary muscles in the heart chamber and remains in this. Bei dieser Ausgestaltung müssen die Verbindungselemente naturgemäß von den Plat tenelementen lösbar, vorzugsweise herausziehbar ausge bildet sein. In this embodiment, the connecting elements must naturally tenelementen detachable from the Plat, preferably pulled out forms to be.

Weiter können besondere, sich von dem Haltering nach oben erstreckende Ösen vorgesehen sein, die zum Einfüh ren des Halters in die Herzkammer unter Verwendung eines besonderen Instruments dienen. Further, particularly, to be provided by the retainer ring upwardly extending eyelets for ren troduction of the holder are in the heart chamber using a special instrument.

Vorgeschlagen wird weiter ein Behälter zur Aufnahme des Halters, der aus einer zylindrischen Außenwandung und einer quer zu dieser verlaufenden Trennwand besteht, wobei die Trennwand mit einer der Form des Halterings entsprechenden Ausnehmung versehen ist. is proposed further comprising a container for receiving the holder which consists of a cylindrical outer wall and a partition wall extending transversely to this, wherein the dividing wall with the shape of the retaining ring is provided corresponding recess.

Weitere Merkmale und Vorteile der Erfindung ergeben sich aus der Zeichnung, in der ein Ausführungsbeispiel des erfindungsgemäßen Halters anhand einer Zeichnung erläutert wird. Further features and advantages of the invention will be apparent from the drawing, in which an embodiment of the holder according to the invention is explained with reference to a drawing. Dabei zeigt Here shows

Fig. 1 eine perspektivische Darstellung des Halters, und Fig. 1 is a perspective view of the holder, and

Fig. 2 eine entsprechende Darstellung mit in den Halter eingesetztem Mitralapparat. Fig. 2 is a representation corresponding with inserted into the holder Mitralapparat.

Der Halter besteht aus einem Haltering 10 , dessen Form dem des humanen Mitralklappenrings entspricht. The holder consists of a holding ring 10, whose shape corresponds to that of the human mitral valve annulus. An dem Haltering 10 sind mittels jeweils einem aus einem Me talldraht gefertigten Verbindungselement zwei Platten elemente 14 befestigt. Two plates members 14 attached to the retaining ring 10 by means of a respective talldraht made of a connecting element Me. Der Abstand der Plattenelemente 14 von dem Haltering 10 entspricht dabei dem Abstand zwischen dem Mitralklappenring und den Papillarmuskeln des zu implantierenden Mitralklappenapparates und kann durch eine entsprechende Biegung der Verbindungselemen te nach innen verkürzt werden. The distance between the plate members 14 of the retaining ring 10 corresponds to the distance between the mitral valve annulus and the papillary muscles of the mitral valve to be implanted and can be shortened on the inside by a corresponding bending of the Verbindungselemen te.

Der Haltering 10 ist auf seiner Innenseite mit einer zur Aufnahme eines Klemmrings 16 dienenden Innennut 18 versehen, zwischen dem und der Innenwandung des Halterings 10 das Implantat eingeklemmt wird, wie dies aus Fig. 2 deutlich wird. The retaining ring 10 is provided on its inside with a serving for receiving a clamping ring 16 inside groove 18, the implant is clamped between the inner wall and the retaining ring 10, as is clear from FIG. 2.

Die Plattenelemente 14 sind mit seitlichen Ausnehmungen versehen, durch die eine Markierung des Vernähungsortes bei dem Anpassen des Implantats - beispielsweise durch einen Markierungsstich - möglich wird. The plate members 14 are provided with lateral recesses, through which a marker of Vernähungsortes wherein the adjusting of the implant - for example by a stitch mark - is possible.

Die Plattenelemente 14 können aus einem gewebefreund lichen Teflonfilz hergestellt sein, wobei die Papillar muskeln des Implantats auf diesen aufgenäht sind. The plate elements 14 may be made of a tissue handy friend Teflon felt, with the papillary muscles of the implant are sewn onto it. Der Teflonfilz wird sodann an dem Papillarmuskelkopf ver näht und verbleibt in dem Herzen. The Teflon felt is then sewn to the ver Papillarmuskelkopf and remains in the heart. Bei dieser Ausfüh rungsform müssen die Verbindungselemente 12 natürlich von den Plattenelementen 14 lösbar sind, beispielsweise aus den Plattenelementen 14 herausgezogen werden kön nen. In this exporting approximately form the connecting elements have to be detached from the plate members 14, Kgs be pulled out, for example, the plate members 14 nen 12 naturally.

In der Zeichnung sind weiter zwei Halteösen 20 wieder gegeben, die nach oben weisend an den Haltering 10 angesetzt sind und das Einführen des Halters in die Herzkammer erleichtern. In the drawing, two eyelets 20 are passed back, which are attached facing up on the retaining ring 10 and facilitate the insertion of the holder into the heart chamber.

Der vorgeschlagene Halter erleichtert die Handhabung ungerahmter biologischer Mitralklappenapparate, sie können in diesen präpariert, konserviert, aufbewahrt und eingepaßt werden sowie bei der Vernähung des Im plantats in das Herz verwendet werden. The proposed holder facilitates handling unframed biological Mitralklappenapparate, they can prepared in these conserved, preserved and are fitted and are of use in suturing in plantats in the heart.

Die vorgeschlagenen Halter können weiter vor dem Einnä hen des Implantats zum Maßnehmen verwendet werden. The proposed holders may continue to be used before the Einnä hen of the implant for taking measurements. Zu diesem Zweck verfügt der Operateur über einen Satz verschieden großer Halter, die zu Vergleichszwecken nacheinander in die Herzkammer eingesetzt werden. To this end, the operator has a set of different sized holder, which are used for comparison purposes in succession into the heart chamber.

Claims (9)

1. Halter für ein ungerahmtes biologisches Mitral klappenimplantat, gekennzeichnet durch einen in Form eines menschlichen Mitralklappenringes ausgebildeten Haltering ( 10 ) und zwei mittels jeweils einem aus einem biegsamen Material bestehenden Verbindungselementen ( 12 ) an dem Haltering ( 10 ) befestigte Plattenelemente ( 14 ), wobei der Abstand der Plattenelemente ( 14 ) von dem Haltering ( 10 ) dem Abstand zwischen dem Mitral klappenring und den Papillarmuskeln des zu implantie renden Mitralklappenimplantats entspricht. 1. Holder for an unframed biological mitral valve implant, characterized by a formed in the shape of a human mitral valve annulus retaining ring (10) and two by means of each one consisting of a flexible material connection elements (12) on the retaining ring (10) attached to the plate elements (14), wherein the distance between the plate members (14) of the retaining ring (10) folded ring to the distance between the mitral and corresponds to the papillary muscles of the leaders to implantie Mitralklappenimplantats.
2. Halter nach Anspruch 1, dadurch gekennzeichnet, daß der Haltering ( 10 ) mit einer zur Aufnahme eines Klemmrings ( 16 ) dienenden Innennut ( 18 ) versehen ist. 2. Holder according to claim 1, characterized in that the retaining ring (10) serving with an for receiving a clamping ring (16) internal groove (18) is provided.
3. Halter nach Anspruch 1 oder 2, dadurch gekenn zeichnet, daß der Haltering ( 10 ) aus einem Kunststoff besteht. 3. Holder according to claim 1 or 2, characterized in that the retaining ring (10) consists of a plastic.
4. Halter nach einem der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Verbindungselemente ( 12 ) aus Metalldraht bestehen. 4. Holder according to one of the preceding claims, characterized in that the connecting elements (12) consist of metal wire.
5. Halter nach einem der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Plattenelemente ( 14 ) mit seitlichen, eine Markierung des Einnäherungsortes der Papillarmuskeln ermöglichenden Ausnehmungen versehen sind. 5. Holder according to one of the preceding claims, characterized in that the plate elements (14) are provided with lateral, enabling a marker of the papillary muscles Einnäherungsortes recesses.
6. Halter nach einem der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Plattenelemente ( 14 ) aus einem Teflonfilz bestehen. 6. Holder according to one of the preceding claims, characterized in that the plate elements (14) consist of a Teflon felt.
7. Halter nach einem der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Verbindungselemente ( 12 ) von den Plattenelementen ( 14 ) lösbar sind. 7. Holder according to one of the preceding claims, characterized in that the connecting elements (12) of the plate elements (14) are releasable.
8. Halter nach Anspruch 6, dadurch gekennzeichnet, daß die Verbindungselemente ( 12 ) aus den Plattenelemen ten ( 14 ) herausziehbar ausgebildet sind. 8. Holder according to claim 6, characterized in that the connecting elements (12) from the Plattenelemen ten (14) are pulled out.
9. Halter nach einem der vorangehenden Ansprüche, gekennzeichnet durch zwei auf den Haltering ( 10 ) aufge setzte, nach oben weisende Halteösen ( 20 ). 9. Holder set up according to one of the preceding claims, characterized by two on the retaining ring (10), upwardly facing attachment points (20).
DE3614292A 1986-04-26 1986-04-26 Holder for unframed biological mitral valve implant Expired DE3614292C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE3614292A DE3614292C1 (en) 1986-04-26 1986-04-26 Holder for unframed biological mitral valve implant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3614292A DE3614292C1 (en) 1986-04-26 1986-04-26 Holder for unframed biological mitral valve implant

Publications (1)

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DE3614292C1 true DE3614292C1 (en) 1987-11-19

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DE3614292A Expired DE3614292C1 (en) 1986-04-26 1986-04-26 Holder for unframed biological mitral valve implant

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Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0532678A4 (en) * 1990-06-07 1993-07-28 Robert William Mayo Frater Mitral heart valve replacements
DE4234127A1 (en) * 1992-10-09 1994-05-26 Vetter Herbert Dr Heart valve prosthesis - comprises distributor mitral valve which can be fixed to heart wall with aid of plastic patches
WO1997020524A1 (en) * 1995-12-01 1997-06-12 Medtronic, Inc. Physiologic mitral valve bioprosthesis
US5733331A (en) * 1992-07-28 1998-03-31 Newcor Industrial S.A. Total mitral heterologous bioprosthesis to be used in mitral or tricuspid heat replacement
US6165119A (en) * 1997-01-02 2000-12-26 Myocor, Inc. Heart wall tension reduction apparatus and method
US6261222B1 (en) 1997-01-02 2001-07-17 Myocor, Inc. Heart wall tension reduction apparatus and method
US6283993B1 (en) 1989-07-31 2001-09-04 Edwards Lifesciences Corporation Annuloplasty ring delivery system
US6332893B1 (en) * 1997-12-17 2001-12-25 Myocor, Inc. Valve to myocardium tension members device and method
US6402679B1 (en) * 1998-09-21 2002-06-11 Myocor, Inc. External stress reduction device and method
US6402680B2 (en) 1998-07-29 2002-06-11 Myocor, Inc. Stress reduction apparatus and method
US6406420B1 (en) 1997-01-02 2002-06-18 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US6537198B1 (en) 2000-03-21 2003-03-25 Myocor, Inc. Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly
US6622730B2 (en) 2001-03-30 2003-09-23 Myocor, Inc. Device for marking and aligning positions on the heart
US6723038B1 (en) 2000-10-06 2004-04-20 Myocor, Inc. Methods and devices for improving mitral valve function
US6746471B2 (en) 1998-07-29 2004-06-08 Myocor, Inc. Transventricular implant tools and devices
US6764510B2 (en) 2002-01-09 2004-07-20 Myocor, Inc. Devices and methods for heart valve treatment
US7213601B2 (en) 1993-02-22 2007-05-08 Heartport, Inc Minimally-invasive devices and methods for treatment of congestive heart failure
US7316712B2 (en) 1999-12-30 2008-01-08 St. Jude Medical, Inc. Tissue heart valve with annulus support structure
US7666224B2 (en) 2002-11-12 2010-02-23 Edwards Lifesciences Llc Devices and methods for heart valve treatment
US7883539B2 (en) 1997-01-02 2011-02-08 Edwards Lifesciences Llc Heart wall tension reduction apparatus and method
US8092367B2 (en) 2001-09-07 2012-01-10 Mardil, Inc. Method for external stabilization of the base of the heart
US8142495B2 (en) 2006-05-15 2012-03-27 Edwards Lifesciences Ag System and a method for altering the geometry of the heart
WO2012004679A3 (en) * 2010-07-09 2012-08-23 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US8506624B2 (en) 2002-01-09 2013-08-13 Edwards Lifesciences, Llc Devices and methods for heart valve treatment
US9107749B2 (en) 2010-02-03 2015-08-18 Edwards Lifesciences Corporation Methods for treating a heart

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS ERMITTELT *

Cited By (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6802860B2 (en) 1989-07-31 2004-10-12 Edwards Lifesciences Corporation Annuloplasty ring delivery system
US6283993B1 (en) 1989-07-31 2001-09-04 Edwards Lifesciences Corporation Annuloplasty ring delivery system
US6558416B2 (en) 1989-07-31 2003-05-06 Edwards Lifesciences Corporation Annuloplasty ring delivery method
EP0532678A4 (en) * 1990-06-07 1993-07-28 Robert William Mayo Frater Mitral heart valve replacements
US5733331A (en) * 1992-07-28 1998-03-31 Newcor Industrial S.A. Total mitral heterologous bioprosthesis to be used in mitral or tricuspid heat replacement
DE4234127A1 (en) * 1992-10-09 1994-05-26 Vetter Herbert Dr Heart valve prosthesis - comprises distributor mitral valve which can be fixed to heart wall with aid of plastic patches
US7213601B2 (en) 1993-02-22 2007-05-08 Heartport, Inc Minimally-invasive devices and methods for treatment of congestive heart failure
US5824067A (en) * 1995-12-01 1998-10-20 Medtronic, Inc. Physiologic mitral valve bioprosthesis
WO1997020524A1 (en) * 1995-12-01 1997-06-12 Medtronic, Inc. Physiologic mitral valve bioprosthesis
US8267852B2 (en) 1997-01-02 2012-09-18 Edwards Lifesciences, Llc Heart wall tension reduction apparatus and method
US6332864B1 (en) 1997-01-02 2001-12-25 Myocor, Inc. Heart wall tension reduction apparatus
US6332863B1 (en) 1997-01-02 2001-12-25 Myocor, Inc. Heart wall tension reduction kit
US8460173B2 (en) 1997-01-02 2013-06-11 Edwards Lifesciences, Llc Heart wall tension reduction apparatus and method
US6793618B2 (en) 1997-01-02 2004-09-21 Myocor, Inc. Heart wall tension reduction apparatus
US6406420B1 (en) 1997-01-02 2002-06-18 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US6514194B2 (en) 1997-01-02 2003-02-04 Myocor, Inc. Heart wall tension reduction apparatus and method
US7695425B2 (en) 1997-01-02 2010-04-13 Edwards Lifesciences Llc Heart wall tension reduction apparatus and method
US6165120A (en) * 1997-01-02 2000-12-26 Myocor, Inc. Heart wall tension reduction apparatus and method
US6589160B2 (en) 1997-01-02 2003-07-08 Myocor, Inc. Heart wall tension reduction apparatus
US6755777B2 (en) 1997-01-02 2004-06-29 Myocor, Inc. Heart wall tension reduction apparatus and method
US6629921B1 (en) 1997-01-02 2003-10-07 Myocor, Inc. Heart wall tension reduction apparatus and method
US6165119A (en) * 1997-01-02 2000-12-26 Myocor, Inc. Heart wall tension reduction apparatus and method
US7883539B2 (en) 1997-01-02 2011-02-08 Edwards Lifesciences Llc Heart wall tension reduction apparatus and method
US6261222B1 (en) 1997-01-02 2001-07-17 Myocor, Inc. Heart wall tension reduction apparatus and method
US8187323B2 (en) 1997-12-17 2012-05-29 Edwards Lifesciences, Llc Valve to myocardium tension members device and method
US8226711B2 (en) 1997-12-17 2012-07-24 Edwards Lifesciences, Llc Valve to myocardium tension members device and method
US6332893B1 (en) * 1997-12-17 2001-12-25 Myocor, Inc. Valve to myocardium tension members device and method
EP1637091A3 (en) * 1997-12-17 2010-09-22 Edwards Lifesciences AG Valve to myocardium tension members device and method
US7981020B2 (en) 1998-07-29 2011-07-19 Edwards Lifesciences Llc Transventricular implant tools and devices
US8439817B2 (en) 1998-07-29 2013-05-14 Edwards Lifesciences, Llc Chordae capturing methods for stress reduction
US6402680B2 (en) 1998-07-29 2002-06-11 Myocor, Inc. Stress reduction apparatus and method
US7722523B2 (en) 1998-07-29 2010-05-25 Edwards Lifesciences Llc Transventricular implant tools and devices
US6746471B2 (en) 1998-07-29 2004-06-08 Myocor, Inc. Transventricular implant tools and devices
US8579798B2 (en) 1998-09-21 2013-11-12 Edwards Lifesciences, Llc External cardiac stress reduction method
US6402679B1 (en) * 1998-09-21 2002-06-11 Myocor, Inc. External stress reduction device and method
US6808488B2 (en) 1998-09-21 2004-10-26 Myocor, Inc. External stress reduction device and method
US7316712B2 (en) 1999-12-30 2008-01-08 St. Jude Medical, Inc. Tissue heart valve with annulus support structure
US6537198B1 (en) 2000-03-21 2003-03-25 Myocor, Inc. Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly
US6723038B1 (en) 2000-10-06 2004-04-20 Myocor, Inc. Methods and devices for improving mitral valve function
US9198757B2 (en) 2000-10-06 2015-12-01 Edwards Lifesciences, Llc Methods and devices for improving mitral valve function
US7766812B2 (en) 2000-10-06 2010-08-03 Edwards Lifesciences Llc Methods and devices for improving mitral valve function
US6622730B2 (en) 2001-03-30 2003-09-23 Myocor, Inc. Device for marking and aligning positions on the heart
US9289298B2 (en) 2001-09-07 2016-03-22 Mardil, Inc. Method and apparatus for external stabilization of the heart
US8128553B2 (en) 2001-09-07 2012-03-06 Mardil, Inc. Method and apparatus for external stabilization of the heart
US8715160B2 (en) 2001-09-07 2014-05-06 Mardil, Inc. Method and apparatus for external stabilization of the heart
US8092367B2 (en) 2001-09-07 2012-01-10 Mardil, Inc. Method for external stabilization of the base of the heart
US8070805B2 (en) 2002-01-09 2011-12-06 Edwards Lifesciences Llc Devices and methods for heart valve treatment
US6764510B2 (en) 2002-01-09 2004-07-20 Myocor, Inc. Devices and methods for heart valve treatment
US7678145B2 (en) 2002-01-09 2010-03-16 Edwards Lifesciences Llc Devices and methods for heart valve treatment
US8506624B2 (en) 2002-01-09 2013-08-13 Edwards Lifesciences, Llc Devices and methods for heart valve treatment
US7666224B2 (en) 2002-11-12 2010-02-23 Edwards Lifesciences Llc Devices and methods for heart valve treatment
US8591576B2 (en) 2006-05-15 2013-11-26 Edwards Lifesciences Ag Method for altering the geometry of the heart
US8142495B2 (en) 2006-05-15 2012-03-27 Edwards Lifesciences Ag System and a method for altering the geometry of the heart
US9107749B2 (en) 2010-02-03 2015-08-18 Edwards Lifesciences Corporation Methods for treating a heart
WO2012004679A3 (en) * 2010-07-09 2012-08-23 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
EP2962664A1 (en) * 2010-07-09 2016-01-06 Highlife SAS Transcatheter atrio-ventricular valve prosthesis

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