DE3587227D1 - Antidiabetikaverbindungen. - Google Patents

Antidiabetikaverbindungen.

Info

Publication number
DE3587227D1
DE3587227D1 DE8585304162T DE3587227T DE3587227D1 DE 3587227 D1 DE3587227 D1 DE 3587227D1 DE 8585304162 T DE8585304162 T DE 8585304162T DE 3587227 T DE3587227 T DE 3587227T DE 3587227 D1 DE3587227 D1 DE 3587227D1
Authority
DE
Germany
Prior art keywords
diabetic compounds
compounds
present
diabetic
insulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585304162T
Other languages
English (en)
Other versions
DE3587227T2 (de
Inventor
Bruce Hill Frank
Allen Howard Pekar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE3587227D1 publication Critical patent/DE3587227D1/de
Application granted granted Critical
Publication of DE3587227T2 publication Critical patent/DE3587227T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8585304162T 1984-06-14 1985-06-12 Antidiabetikaverbindungen. Expired - Fee Related DE3587227T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/620,780 US4569792A (en) 1984-06-14 1984-06-14 Anti-diabetic compounds

Publications (2)

Publication Number Publication Date
DE3587227D1 true DE3587227D1 (de) 1993-05-06
DE3587227T2 DE3587227T2 (de) 1993-08-12

Family

ID=24487358

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585304162T Expired - Fee Related DE3587227T2 (de) 1984-06-14 1985-06-12 Antidiabetikaverbindungen.

Country Status (8)

Country Link
US (1) US4569792A (de)
EP (1) EP0171886B1 (de)
JP (1) JPH0633318B2 (de)
AT (1) ATE87662T1 (de)
CA (1) CA1244366A (de)
DE (1) DE3587227T2 (de)
DK (1) DK262485A (de)
MX (1) MX9203125A (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888414A (en) * 1987-04-09 1989-12-19 Board Of Regents, University Of Texas System Insulin-binding peptides and uses thereof
US4992418A (en) * 1987-07-17 1991-02-12 Mount Sinai School Of Medicine Superactive human insulin analogue-[10-Aspartic Acid-B]Human Insulin
US4992417A (en) * 1987-07-17 1991-02-12 Mount Sinai School Of Medicine Superactive human insulin analogues
US5208217A (en) * 1989-04-20 1993-05-04 Mount Sinai School Of Medicine Of The City University Of New York Hepatospecific insulin analogues
US5130236A (en) * 1989-12-07 1992-07-14 Eli Lilly And Company Process for producing des(64,65)-proinsulin
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
NZ245170A (en) * 1991-11-26 1994-07-26 Lilly Co Eli Insulin and proinsulin analogues with arg at b31, b32 and ao and pharmaceutical compositions
US6818217B1 (en) 1995-02-20 2004-11-16 Amrad Corporation Limited Immunoreactive peptides
JP2003528149A (ja) 2000-03-24 2003-09-24 ジェネンテック・インコーポレーテッド 軟骨性疾患の治療のためのインスリンの使用
JP2012531017A (ja) 2009-06-19 2012-12-06 スリーエム イノベイティブ プロパティズ カンパニー 遮蔽された電気ケーブル
US9685259B2 (en) 2009-06-19 2017-06-20 3M Innovative Properties Company Shielded electrical cable
TWI400376B (zh) * 2010-06-25 2013-07-01 Inprotex Co Ltd Sun light can cloth
CN101906696B (zh) * 2010-07-16 2012-09-19 吴国林 防晒光能布
KR20200080747A (ko) * 2018-12-27 2020-07-07 주식회사 폴루스 인슐린 전구체의 인슐린 효소 전환용 조성물 및 이를 이용하여 인슐린 전구체를 인슐린으로 전환하는 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430266A (en) 1980-11-28 1984-02-07 Eli Lilly And Company Process for producing an insulin precursor
DE3209184A1 (de) * 1982-03-13 1983-09-15 Hoechst Ag, 6230 Frankfurt Verfahren zur umwandlung von praeproinsulinanaloga zu insulinen
JPS58183659A (ja) * 1982-03-31 1983-10-26 ジェネテイックス、インスチチュ−ト、インコ−ポレ−テッド 修飾プロインシュリン前駆体、これを暗号化するｄｎａ配列およびそれらの産生方法

Also Published As

Publication number Publication date
ATE87662T1 (de) 1993-04-15
MX9203125A (es) 1992-07-01
US4569792A (en) 1986-02-11
EP0171886A3 (en) 1989-01-25
CA1244366A (en) 1988-11-08
DK262485A (da) 1985-12-15
DK262485D0 (da) 1985-06-12
JPH0633318B2 (ja) 1994-05-02
JPS6133198A (ja) 1986-02-17
DE3587227T2 (de) 1993-08-12
EP0171886A2 (de) 1986-02-19
EP0171886B1 (de) 1993-03-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee