DE3483332D1 - Verfahren und vorrichtung zum abtrennen von blutlymphozyten aus blut. - Google Patents
Verfahren und vorrichtung zum abtrennen von blutlymphozyten aus blut.Info
- Publication number
- DE3483332D1 DE3483332D1 DE8484300435T DE3483332T DE3483332D1 DE 3483332 D1 DE3483332 D1 DE 3483332D1 DE 8484300435 T DE8484300435 T DE 8484300435T DE 3483332 T DE3483332 T DE 3483332T DE 3483332 D1 DE3483332 D1 DE 3483332D1
- Authority
- DE
- Germany
- Prior art keywords
- blood
- separating
- lymphocytes
- blood lymphocytes
- separating blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000004369 blood Anatomy 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 210000004698 lymphocyte Anatomy 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D43/00—Separating particles from liquids, or liquids from solids, otherwise than by sedimentation or filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Ecology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/467,640 US4487700A (en) | 1983-02-18 | 1983-02-18 | Method and apparatus for separating lymphocytes from anticoagulated blood |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3483332D1 true DE3483332D1 (de) | 1990-11-08 |
Family
ID=23856512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484300435T Expired - Fee Related DE3483332D1 (de) | 1983-02-18 | 1984-01-25 | Verfahren und vorrichtung zum abtrennen von blutlymphozyten aus blut. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4487700A (de) |
EP (1) | EP0119692B1 (de) |
JP (1) | JPS59154362A (de) |
AU (1) | AU560898B2 (de) |
CA (1) | CA1210693A (de) |
DE (1) | DE3483332D1 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4666850A (en) * | 1983-10-28 | 1987-05-19 | Becton, Dickinson And Company | Microbial pathogen detecting system and process |
US4818418A (en) * | 1984-09-24 | 1989-04-04 | Becton Dickinson And Company | Blood partitioning method |
US4751001A (en) * | 1984-09-24 | 1988-06-14 | Becton Dickinson And Company | Blood partitioning apparatus |
US4917801A (en) * | 1984-12-04 | 1990-04-17 | Becton Dickinson And Company | Lymphocyte collection tube |
US5053134A (en) * | 1984-12-04 | 1991-10-01 | Becton Dickinson And Company | Lymphocyte collection tube |
US4640785A (en) * | 1984-12-24 | 1987-02-03 | Becton Dickinson And Company | Separation of lymphocytes and monocytes from blood samples |
US4927750A (en) * | 1986-04-09 | 1990-05-22 | Jeanette Simpson | Cell separation process |
US4927749A (en) * | 1986-04-09 | 1990-05-22 | Jeanette Simpson | Reagent for cell separation |
DE3616728A1 (de) * | 1986-05-17 | 1987-11-19 | Strahlen Umweltforsch Gmbh | Verfahren und vorrichtung zur isolierung von fraktionen von makromolekuelen aus dichtegradienten |
US4744907A (en) * | 1987-01-16 | 1988-05-17 | Interferon Sciences, Inc. | Blood cell separation |
US5223398A (en) * | 1987-03-13 | 1993-06-29 | Coulter Corporation | Method for screening cells or formed bodies for enumeration of populations expressing selected characteristics |
US5238812A (en) * | 1987-03-13 | 1993-08-24 | Coulter Corporation | Method and apparatus for rapid mixing of small volumes for enhancing biological reactions |
US4939081A (en) * | 1987-05-27 | 1990-07-03 | The Netherlands Cancer Institute | Cell-separation |
US4844818A (en) * | 1987-10-23 | 1989-07-04 | Becton Dickinson & Company | Method for separating the cellular components of blood samples |
US4957638A (en) * | 1987-10-23 | 1990-09-18 | Becton Dickinson And Company | Method for separating the cellular components of blood samples |
US4867887A (en) * | 1988-07-12 | 1989-09-19 | Becton Dickinson And Company | Method and apparatus for separating mononuclear cells from blood |
US4954264A (en) * | 1989-02-02 | 1990-09-04 | Becton-Dickinson And Company | Apparatus for separating mononuclear cells from blood and method of manufacturing and using the same |
US4994393A (en) * | 1989-02-22 | 1991-02-19 | Becton, Dickinson And Company | Blood partitioning composition |
CA2013021C (en) * | 1989-11-29 | 1995-05-09 | Richard Lewis Columbus | Blood collection device |
US5039401A (en) * | 1990-05-16 | 1991-08-13 | Eastman Kodak Company | Blood collection and centrifugal separation device including a valve |
US5724091A (en) | 1991-11-25 | 1998-03-03 | Actv, Inc. | Compressed digital data interactive program system |
US5576185A (en) | 1994-04-15 | 1996-11-19 | Coulter Corporation | Method of positive or negative selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation |
US5599501A (en) * | 1994-11-10 | 1997-02-04 | Ciba Corning Diagnostics Corp. | Incubation chamber |
JP2000500337A (ja) * | 1995-11-13 | 2000-01-18 | コールター コーポレイション | 細胞の集団又は亜集団のバルク濃縮のための方法および装置 |
JP2000500388A (ja) * | 1995-11-13 | 2000-01-18 | コールター インターナショナル コーポレイション | 粒子および重力沈降を使用するサンプルの集団または下位集団を選択する方法 |
US5840878A (en) * | 1996-03-12 | 1998-11-24 | Becton Dickinson And Company | Vehicle for delivery of particles to a sample |
US7947236B2 (en) | 1999-12-03 | 2011-05-24 | Becton, Dickinson And Company | Device for separating components of a fluid sample |
JP4128007B2 (ja) | 2000-04-28 | 2008-07-30 | ハーベスト・テクノロジーズ・コーポレイション | 血液成分分離用ディスク |
US20060018799A1 (en) * | 2004-07-21 | 2006-01-26 | Wong Cai Ne W | Universal tissue homogenizer device and methods |
US7673758B2 (en) * | 2005-08-10 | 2010-03-09 | The Regents Of The University Of California | Collection tubes apparatus, systems, and methods |
CN102149473B (zh) | 2008-07-21 | 2014-12-31 | 贝克顿·迪金森公司 | 密度相分离装置 |
JP5638603B2 (ja) | 2009-05-15 | 2014-12-10 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 密度相分離デバイス |
WO2012086243A1 (ja) * | 2010-12-21 | 2012-06-28 | 株式会社 島津製作所 | 管内で対象成分を操作するためのデバイス及び方法 |
EP2836245B1 (de) | 2012-04-12 | 2018-06-06 | President and Fellows of Harvard College | Verfahren zur isolierung von leukozyten |
US9694359B2 (en) | 2014-11-13 | 2017-07-04 | Becton, Dickinson And Company | Mechanical separator for a biological fluid |
US11291931B2 (en) | 2014-12-15 | 2022-04-05 | Akadeum Life Sciences, Inc. | Method and system for buoyant separation |
EP3233232A4 (de) | 2014-12-15 | 2018-11-14 | Akadeum Life Sciences LLC | Verfahren und system zur schwimmenden trennung |
CN107475094B (zh) * | 2017-08-11 | 2021-01-26 | 河南科技大学第一附属医院 | 一种血细胞分离管和分离方法 |
US20200009614A1 (en) | 2018-07-09 | 2020-01-09 | Akadeum Life Sciences, Inc. | System and method for buoyant particle processing |
CN115280145A (zh) * | 2020-03-11 | 2022-11-01 | 积水医疗株式会社 | 白细胞浓缩分离设备、血液采集容器和白细胞的分离方法 |
EP4392158A1 (de) | 2021-08-26 | 2024-07-03 | Akadeum Life Sciences, Inc. | Verfahren und system zur schwimmenden trennung |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3700555A (en) * | 1970-10-12 | 1972-10-24 | Technicon Instr | Method and apparatus for lymphocyte separation from blood |
US3709791A (en) * | 1971-04-13 | 1973-01-09 | Technicon Instr | Method and apparatus for lymphocyte separation from blood |
US3852194A (en) * | 1972-12-11 | 1974-12-03 | Corning Glass Works | Apparatus and method for fluid collection and partitioning |
US3814687A (en) * | 1973-06-01 | 1974-06-04 | Honeywell Inc | Blood platelet separation |
US3919085A (en) * | 1974-02-27 | 1975-11-11 | Becton Dickinson Co | Plasma separator assembly |
US4021340A (en) * | 1975-11-28 | 1977-05-03 | Corning Glass Works | Blood separating composition |
US4190535A (en) * | 1978-02-27 | 1980-02-26 | Corning Glass Works | Means for separating lymphocytes and monocytes from anticoagulated blood |
JPS54155891A (en) * | 1978-05-30 | 1979-12-08 | Asahi Chemical Ind | Specificcselection adsorbent |
US4250041A (en) * | 1979-06-25 | 1981-02-10 | Warner-Lambert Company | Removal of heparin from blood plasma samples using an insoluble protamine reaction product |
US4310430A (en) * | 1979-09-11 | 1982-01-12 | Terumo Corporation | α-Olefin-dialkylmaleate-based liquid separating agent |
DE3009126A1 (de) * | 1980-03-10 | 1981-10-08 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Verfahren zur gewinnung von funktionell und morphologisch intakten und lebensfaehigen leukozyten aus blut |
-
1983
- 1983-02-18 US US06/467,640 patent/US4487700A/en not_active Expired - Lifetime
-
1984
- 1984-01-20 CA CA000445739A patent/CA1210693A/en not_active Expired
- 1984-01-25 EP EP84300435A patent/EP0119692B1/de not_active Expired - Lifetime
- 1984-01-25 DE DE8484300435T patent/DE3483332D1/de not_active Expired - Fee Related
- 1984-01-31 AU AU23908/84A patent/AU560898B2/en not_active Ceased
- 1984-02-10 JP JP59022058A patent/JPS59154362A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
US4487700A (en) | 1984-12-11 |
AU2390884A (en) | 1984-08-23 |
JPH0442627B2 (de) | 1992-07-14 |
EP0119692B1 (de) | 1990-10-03 |
AU560898B2 (en) | 1987-04-16 |
CA1210693A (en) | 1986-09-02 |
EP0119692A3 (en) | 1986-10-29 |
EP0119692A2 (de) | 1984-09-26 |
JPS59154362A (ja) | 1984-09-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |