DE328598C - Process for the production of Kolapreparaten - Google Patents
Process for the production of KolapreparatenInfo
- Publication number
- DE328598C DE328598C DE1919328598D DE328598DD DE328598C DE 328598 C DE328598 C DE 328598C DE 1919328598 D DE1919328598 D DE 1919328598D DE 328598D D DE328598D D DE 328598DD DE 328598 C DE328598 C DE 328598C
- Authority
- DE
- Germany
- Prior art keywords
- alkaloids
- phosphoric acid
- cola
- production
- glycerol phosphoric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
Verfahren zur Herstellung von Kolapräparaten. Es ist bekännt, daß sich Verbindungen der Alkaloide mit Glyzerinphosphorsäure gegenüber Verbindungen derselben mit Mineralsäuren . durch besonders gute und schnelle Wirkung auszeichnen. Diese schnellere, bessere und ausgiebigere Wirkung ist darauf zurückzuführen, daß die glyzerinphosphorsauren Verbindungen direkt assimilierbar sind.Process for the production of cola preparations. It is known that compounds of alkaloids with glycerol phosphoric acid versus compounds the same with mineral acids. characterized by particularly good and fast effect. This faster, better and more extensive effect is due to the fact that the glycerol phosphoric acid compounds are directly assimilable.
Die Aufgabe der Erfindung war, die in den Kolanüssen enthaltenen Alkaloide (Koffein und Theobromin) in dem Kolapulver selbst in die glyzerinphosphorsauren Verbindungen überzuführen, um eine bessere Wirkung der Alkaloide zu erzielen und gleichzeitig Alkaloide mit einer an und für sich wirksamen Komponente - der Glyzerinphosphorsäure - zu vereinigen.The object of the invention was to find the alkaloids contained in the kola nuts (Caffeine and theobromine) in the cola powder itself into the glycerol phosphoric acids Transfer compounds in order to achieve a better effect of the alkaloids and at the same time alkaloids with a component that is effective in and of itself - glycerol phosphoric acid - to unite.
Während die Alkaloide der Kolanuß lediglich eine die Nerven anregende Wirkung besitzen, haben dagegen diese Alkaloide in Verbindung mit der Glyzerinphosphorsäure eine vorzügliche Wirkung auf die Nervenernährung und stehlen jene Form dar, in welcher der Phosphor in den Organismus aufgenommen wird.While the alkaloids of the kola nut only stimulate the nerves However, these alkaloids have an effect in connection with glycerol phosphoric acid an excellent effect on nerve nourishment and steal that form in which the phosphorus is absorbed into the organism.
Durch die gleichzeitige Anregung und Ernährung der Nerven wird, wie die therapeutischen Versuche ergeben haben, der beste Erfolg erzielt.By stimulating and nourishing the nerves at the same time, how which therapeutic attempts have shown the greatest success.
Das Verfahren besteht darin, daß in dem Kolapulver die Alkaloide mittels eines alkalischen Stoffes in Freiheit gesetzt werden, worauf soviel Glyzerinphosphorsäure zugesetzt wird, wie notwendig ist, um sowohl die freigewordenen Alkaloide wie den alkalischen Stoff selbst zu neutralisieren. Als alkalischen Stoff verwendet man am besten Atzkalk, weil den Kalksalzen als solchen schon eine hervorragende Wirkung für den Stoffwechsel zukommt; in dem Kolapulver würden ' demnach glyzerinphosphorsaure Alkaloide und glyzerinphosphorsaurer Kalk erzeugt, und zwar. auf eine sehr einfache und wenig kostspielige Weise.The method consists in that in the cola powder the alkaloids means of an alkaline substance are set free, whereupon so much glycerol phosphoric acid is added as necessary to both the released alkaloids and the neutralize alkaline substance itself. One uses as an alkaline substance best quicklime, because the lime salts as such have an excellent effect for the metabolism; accordingly, the cola powder would contain glycerol phosphoric acid Alkaloids and glycerophosphate produced, namely. on a very simple one and a little expensive way.
Beispiel: i ooo g fein gemahlenes Kolapulver werden mit io g fein gepulvertem Ätzkalk innig gemischt, darauf wird die Mischung mit .30o g Wasser gut durchfeuchtet und einige Stunden stehen gelassen. Hierauf werden 6o g Glyzerinphosphorsäure von 50 Prozent mit 6o g Wasser verdünnt und diese Mischung mit dem feuchten Kolapulver sorgfältig gemischt:. Danach wird getrocknet.Example: 100 g of finely ground kola powder are intimately mixed with 100 g of finely powdered quicklime, then the mixture is thoroughly moistened with .30 g of water and left to stand for a few hours. Then 60 g glycerol phosphoric acid of 50 percent are diluted with 60 g water and this mixture is carefully mixed with the moist cola powder. Then it is dried.
Auf diese Weise erhält man ein Kolapulver, welches neben den unveränderlichen Bestandteilen des Kolasamens die Glyzerophosphate des Koffeins und des Theobromins sowie das Glyzerophosphat des Kalziums enthält.In this way you get a cola powder, which is next to the unchangeable Ingredients of kola seed the glycerophosphates of caffeine and theobromine as well as the glycerophosphate of calcium.
Die Verwendung des Kalziums bietet auch den Vorteil, da$ es als schwäch alkalischer Stoff keine verändernde Wirkung auf die Substanzen der Koianuß ausübt.The use of the calcium also offers the advantage, as a weakly alkaline substance it has no changing effect on the substances the koi nut exercises.
Um einen größeren Gehalt an Kalziumglyzerinphosphat zu erzielen, kann man Ätzkalk Zünd Glyzerinphosphorsäure 'in größeren äquivalenten Mengen zusetzen.To achieve a higher content of calcium glycerol phosphate, you can add quicklime Zünd glycerol phosphoric acid in larger equivalent amounts.
Claims (1)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE328598T | 1919-08-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE328598C true DE328598C (en) | 1920-11-02 |
Family
ID=6186171
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1919328598D Expired DE328598C (en) | 1919-08-02 | 1919-08-02 | Process for the production of Kolapreparaten |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE328598C (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5028428A (en) * | 1988-08-09 | 1991-07-02 | Estee Lauder Inc. | Anti-irritant and desensitizing compositions and methods of their use |
-
1919
- 1919-08-02 DE DE1919328598D patent/DE328598C/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5028428A (en) * | 1988-08-09 | 1991-07-02 | Estee Lauder Inc. | Anti-irritant and desensitizing compositions and methods of their use |
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