DE3278470D1 - 2,6-di(t-butyl)-4-(2'-pyrroyl)phenol and antiinflammatory compositions containing it - Google Patents

2,6-di(t-butyl)-4-(2'-pyrroyl)phenol and antiinflammatory compositions containing it

Info

Publication number
DE3278470D1
DE3278470D1 DE8383900225T DE3278470T DE3278470D1 DE 3278470 D1 DE3278470 D1 DE 3278470D1 DE 8383900225 T DE8383900225 T DE 8383900225T DE 3278470 T DE3278470 T DE 3278470T DE 3278470 D1 DE3278470 D1 DE 3278470D1
Authority
DE
Germany
Prior art keywords
pyrroyl
phenol
butyl
compositions containing
antiinflammatory compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383900225T
Other languages
English (en)
Inventor
George G I Moore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riker Laboratories Inc
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Application granted granted Critical
Publication of DE3278470D1 publication Critical patent/DE3278470D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8383900225T 1981-11-23 1982-11-22 2,6-di(t-butyl)-4-(2'-pyrroyl)phenol and antiinflammatory compositions containing it Expired DE3278470D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/324,061 US4418074A (en) 1981-11-23 1981-11-23 2,6 Di(t-butyl)-4-(2'-pyrrol)-phenol and anti-inflammatory use thereof
PCT/US1982/001636 WO1983001774A1 (en) 1981-11-23 1982-11-22 Substituted pyrrole

Publications (1)

Publication Number Publication Date
DE3278470D1 true DE3278470D1 (en) 1988-06-16

Family

ID=23261896

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383900225T Expired DE3278470D1 (en) 1981-11-23 1982-11-22 2,6-di(t-butyl)-4-(2'-pyrroyl)phenol and antiinflammatory compositions containing it

Country Status (7)

Country Link
US (1) US4418074A (de)
EP (1) EP0094425B1 (de)
JP (1) JPS58502000A (de)
AU (2) AU564875B2 (de)
CA (1) CA1181752A (de)
DE (1) DE3278470D1 (de)
WO (1) WO1983001774A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644009A (en) * 1984-10-29 1987-02-17 Usv Pharmaceutical Corporation Aryl-alkyl heterocyclic compounds
US4833155A (en) * 1986-11-25 1989-05-23 Syntex (U.S.A.) Inc. 3-(ω-(3,5,-di-t-butyl-4-hydroxyphenyl)-alkanoyl)pyrroles, and anti-inflammatory uses thereof
US4935440A (en) * 1986-11-25 1990-06-19 Syntex (U.S.A.) Inc. 3-[ω-(3,5-Di-t-butyl-4-hydroxyphenyl)alkyl]pyrroles, and anti-inflammatory uses thereof
US5476876A (en) * 1994-05-24 1995-12-19 The Procter & Gamble Company Di-tert-butylphenol compounds useful as anti-inflammatory agents
US5684204A (en) * 1995-11-15 1997-11-04 The Procter & Gamble Company Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents
US7479507B2 (en) * 2003-01-14 2009-01-20 Adam Heller Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2171159A (en) * 1938-03-17 1939-08-29 Eastman Kodak Co Azo compounds and process for coloring therewith
US3117129A (en) * 1959-02-18 1964-01-07 American Cyanamid Co Salicyloyl pyridines
ES356485A1 (es) 1967-07-26 1970-01-16 Mcneilab Inc Un procedimiento para la preparacion de nuevos acidos 5- aroilpirrol-2-carboxilicos y derivados de acido carboxilico.
US3803171A (en) * 1972-01-21 1974-04-09 Mc Neil Labor Inc 5-phenylacetyl-pyrroles
US4000160A (en) * 1973-04-11 1976-12-28 Sterling Drug Inc. Pyrrolyl oxyphenyl ketones
US4200645A (en) * 1977-05-10 1980-04-29 Beecham Group Limited Pyrrole derivatives
US4128664A (en) * 1977-05-16 1978-12-05 Riker Laboratories, Inc. Substituted benzamides as anti-inflammatory agents
US4124725A (en) * 1977-05-16 1978-11-07 Riker Laboratories, Inc. Anti-inflammatory method
US4172151A (en) * 1977-05-16 1979-10-23 Riker Laboratories, Inc. Anti-inflammatory method
US4172082A (en) * 1977-05-16 1979-10-23 Riker Laboratories, Inc. Substituted thiophenes
US4222883A (en) * 1978-10-02 1980-09-16 Ethyl Corporation 4,4'-Furfurylidene bis(2,6-di-tert-butylphenol)antioxidant
EP0032314A1 (de) * 1980-01-09 1981-07-22 Beecham Group Plc Aroylpyrrolderivate, Verfahren zu ihrer Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
CA1181752A (en) 1985-01-29
AU564875B2 (en) 1987-08-27
EP0094425B1 (de) 1988-05-11
EP0094425A1 (de) 1983-11-23
WO1983001774A1 (en) 1983-05-26
US4418074A (en) 1983-11-29
JPS58502000A (ja) 1983-11-24
AU1101482A (en) 1983-06-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee