DE3268903D1 - Novel macrolidic antibiotics having antibiotic activity, process and microorganism for their preparation, and related pharmaceutical compositions - Google Patents

Novel macrolidic antibiotics having antibiotic activity, process and microorganism for their preparation, and related pharmaceutical compositions

Info

Publication number
DE3268903D1
DE3268903D1 DE8282200016T DE3268903T DE3268903D1 DE 3268903 D1 DE3268903 D1 DE 3268903D1 DE 8282200016 T DE8282200016 T DE 8282200016T DE 3268903 T DE3268903 T DE 3268903T DE 3268903 D1 DE3268903 D1 DE 3268903D1
Authority
DE
Germany
Prior art keywords
novel
microorganism
preparation
pharmaceutical compositions
erythronolide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282200016T
Other languages
English (en)
Inventor
Leonardo M Cappelletti
Roberto Spagnoli
Luciano Toscano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierrel SpA
Original Assignee
Pierrel SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel SpA filed Critical Pierrel SpA
Application granted granted Critical
Publication of DE3268903D1 publication Critical patent/DE3268903D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/48—Streptomyces antibioticus ; Actinomyces antibioticus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/888—Streptomyces antibioticus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE8282200016T 1981-01-09 1982-01-08 Novel macrolidic antibiotics having antibiotic activity, process and microorganism for their preparation, and related pharmaceutical compositions Expired DE3268903D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8119081A IT1169013B (it) 1981-01-09 1981-01-09 Composti macrolidici ad attivita' antibiotica, procedimento e microorganismo per la loro preparazione e relative composizioni farmaceutiche

Publications (1)

Publication Number Publication Date
DE3268903D1 true DE3268903D1 (en) 1986-03-20

Family

ID=11154383

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282200016T Expired DE3268903D1 (en) 1981-01-09 1982-01-08 Novel macrolidic antibiotics having antibiotic activity, process and microorganism for their preparation, and related pharmaceutical compositions

Country Status (11)

Country Link
US (2) US4429115A (de)
EP (1) EP0056290B1 (de)
JP (1) JPS57138384A (de)
AT (1) ATE17855T1 (de)
BE (1) BE891733A (de)
CA (1) CA1177427A (de)
CH (1) CH663034A5 (de)
DE (1) DE3268903D1 (de)
FI (1) FI72743C (de)
FR (1) FR2502156B1 (de)
IT (1) IT1169013B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502155A1 (fr) * 1981-01-09 1982-09-24 Pierrel Spa Nouveaux antibiotiques macrolides semi-synthetiques, procede microbiologique pour leur preparation et micro-organisme s'y rapportant, nouveaux produits intermediaires pour leur preparation et compositions pharmaceutiques les contenant
US5149639A (en) * 1986-03-24 1992-09-22 Abbott Laboratories Biologically pure cultures of streptomyces and use thereof in macrolide antibiotic production
CA2411293A1 (en) * 1999-01-28 2000-07-28 Pfizer Products Inc. Novel azalides and methods of making same
GB0327720D0 (en) * 2003-11-28 2003-12-31 Biotica Tech Ltd Erythromycins and process for their preparation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA564945A (en) * 1958-10-21 Walter L. Clifton, Jr. Door hinge
US3697547A (en) * 1970-12-18 1972-10-10 Abbott Lab Erythronolide b derivatives
BE793112A (fr) * 1971-12-22 1973-06-21 Ciba Geigy Pyridinium-s-triazines agissant sur la croissance des plantes
US3855200A (en) * 1973-04-23 1974-12-17 Polska Akademia Nauk Instytut Process for preparing 8-hydroxyerthromycin a and intermediates therefor
US3992264A (en) * 1974-02-04 1976-11-16 Hoffmann-La Roche Inc. Antibiotic 1745A/X and methods for the production thereof
US4152424A (en) * 1975-07-23 1979-05-01 Hoffmann-La Roche Inc. Antibiotic 1745A/X and methods for the production thereof
US4069379A (en) 1976-07-08 1978-01-17 Pfizer Inc. Semi-synthetic oleandomycins
US4036853A (en) 1976-08-06 1977-07-19 Pfizer Inc. Semi-synthetic oleandomycin derivatives-C8 modifications
US4085119A (en) 1977-02-04 1978-04-18 Pfizer Inc. 4-Substituted amino derivatives of oleandomycin

Also Published As

Publication number Publication date
EP0056290A2 (de) 1982-07-21
US4560662A (en) 1985-12-24
JPS57138384A (en) 1982-08-26
CA1177427A (en) 1984-11-06
FR2502156B1 (fr) 1986-10-31
JPH0365944B2 (de) 1991-10-15
CH663034A5 (it) 1987-11-13
FI72743B (fi) 1987-03-31
FI72743C (fi) 1987-07-10
US4429115A (en) 1984-01-31
ATE17855T1 (de) 1986-02-15
BE891733A (fr) 1982-04-30
FR2502156A1 (fr) 1982-09-24
IT1169013B (it) 1987-05-20
FI820056L (fi) 1982-07-10
IT8119081A0 (it) 1981-01-09
EP0056290B1 (de) 1986-02-05
EP0056290A3 (en) 1983-01-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee