DE3170401D1 - Triazoline derivatives and processes for their preparation - Google Patents

Triazoline derivatives and processes for their preparation

Info

Publication number
DE3170401D1
DE3170401D1 DE8181810299T DE3170401T DE3170401D1 DE 3170401 D1 DE3170401 D1 DE 3170401D1 DE 8181810299 T DE8181810299 T DE 8181810299T DE 3170401 T DE3170401 T DE 3170401T DE 3170401 D1 DE3170401 D1 DE 3170401D1
Authority
DE
Germany
Prior art keywords
processes
preparation
triazoline
derivatives
triazoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181810299T
Other languages
German (de)
English (en)
Inventor
Hans Prof Dr Zahner
Hans-Ulrich Dr Naegeli
Heinrich Dr Peter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of DE3170401D1 publication Critical patent/DE3170401D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/167—Heterorings having sulfur atoms as ring heteroatoms, e.g. vitamin B1, thiamine nucleus and open chain analogs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/48—Streptomyces antibioticus ; Actinomyces antibioticus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8181810299T 1980-07-28 1981-07-22 Triazoline derivatives and processes for their preparation Expired DE3170401D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH575580 1980-07-28
CH592580 1980-08-05

Publications (1)

Publication Number Publication Date
DE3170401D1 true DE3170401D1 (en) 1985-06-13

Family

ID=25698328

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181810299T Expired DE3170401D1 (en) 1980-07-28 1981-07-22 Triazoline derivatives and processes for their preparation

Country Status (13)

Country Link
US (1) US4406905A (enExample)
EP (1) EP0045281B1 (enExample)
AU (1) AU548331B2 (enExample)
CA (1) CA1172188A (enExample)
DE (1) DE3170401D1 (enExample)
DK (1) DK160304C (enExample)
ES (4) ES8301476A1 (enExample)
GB (1) GB2085873B (enExample)
GR (1) GR74313B (enExample)
IE (1) IE51430B1 (enExample)
IL (1) IL63428A (enExample)
NZ (1) NZ197840A (enExample)
PT (1) PT73439B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU200177B (en) * 1985-06-18 1990-04-28 Biogal Gyogyszergyar Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds
JPS63225373A (ja) * 1986-07-24 1988-09-20 Sumitomo Pharmaceut Co Ltd 新規チアゾリジン−４−オン誘導体およびその酸付加塩
CN1030415A (zh) * 1987-02-20 1989-01-18 山之内制药株式会社 饱和的杂环碳酰胺衍生物和它的制备方法
US4992455A (en) * 1987-05-22 1991-02-12 Sumitomo Pharmaceuticals Company, Limited Thiazolidin-4-one derivatives useful for treating diseases caused by platelet activating factor
ATE98631T1 (de) * 1988-01-20 1994-01-15 Ciba Geigy Ag Verfahren zur herstellung von komplexverbindungen.
US5021435A (en) * 1988-01-22 1991-06-04 Sumitomo Pharmaceuticals Company, Limited Certain pyridyl-thiazolidin-4-one having anti-ulcer activity
AU5602594A (en) * 1992-11-16 1994-06-08 University Of Florida Research Foundation, Inc. 2-(pyrid-2'-yl)-2-thiazoline-4(s)-carboxylic acid derivatives
US5840739A (en) * 1992-11-16 1998-11-24 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
ES2172591T3 (es) * 1994-08-05 2002-10-01 Shionogi & Co Nuevo antibiotico y procedimiento de produccion de este ultimo.
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
WO2000016763A2 (en) * 1998-09-21 2000-03-30 University Of Florida Research Foundation, Inc. Antimalarial agents
AU139723S (en) * 1999-02-09 2000-02-07 Colgate Palmolive Co Container
AT500490A1 (de) * 2001-10-16 2006-01-15 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von substituierten thiazolinen und deren zwischenprodukte
US6903220B2 (en) 2002-05-15 2005-06-07 Genzyme Corporation Synthesis of chiral 2-alkyl amino acids
WO2004031163A1 (ja) * 2002-10-01 2004-04-15 Kaneka Corporation 光学活性α−置換システインまたはその塩の製造方法並びにその合成中間体及びその製造方法
WO2005034949A1 (en) * 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
BRPI0610644B8 (pt) 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
NZ579994A (en) 2007-03-15 2011-09-30 Univ Florida Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal
WO2013090750A1 (en) 2011-12-16 2013-06-20 University Of Florida Research Foundation, Inc. Uses of 4'-desferrithiocin analogs
USD722879S1 (en) 2012-06-14 2015-02-24 S.C. Johnson & Son, Inc. Bottle
USD736089S1 (en) 2012-06-14 2015-08-11 S.C. Johnson & Son, Inc. Bottle
USD736637S1 (en) 2012-06-14 2015-08-18 S.C. Johnson & Son, Inc. Bottle
US10010535B2 (en) 2013-11-22 2018-07-03 University Of Florida Research Foundation, Incorporated Desferrithiocin analogs and uses thereof
CN106660959B (zh) 2014-07-08 2019-12-03 美国陶氏益农公司 3-羟基吡啶甲酸的制备方法
US9522887B2 (en) * 2014-07-08 2016-12-20 Dow Agrosciences Llc Process for the preparation of dibromohydroxypicolinonitrile
KR20170140306A (ko) 2015-04-27 2017-12-20 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 대사적으로 프로그램화된 금속 킬레이트화제 및 그의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592905A (en) * 1969-10-30 1971-07-13 Merck & Co Inc Therapeutic methods
CA962269A (en) * 1971-05-05 1975-02-04 Robert E. Grahame (Jr.) Thiazoles, and their use as insecticides
US3852293A (en) * 1972-06-21 1974-12-03 Uniroyal Inc 4-phenyl-2-(3-pyridyl)-thiazole carboxamides
US3842172A (en) * 1972-10-06 1974-10-15 Uniroyal Inc Pharmaceutical compositions containing a 4-substituted-2-(3-pyridyl)thiazole and methods of using same
FR2356423A1 (fr) * 1976-07-01 1978-01-27 Oeriu Simion Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments

Also Published As

Publication number Publication date
DK335781A (da) 1982-01-29
IE811697L (en) 1982-01-28
US4406905A (en) 1983-09-27
ES514586A0 (es) 1983-11-01
EP0045281A1 (de) 1982-02-03
GB2085873A (en) 1982-05-06
IE51430B1 (en) 1986-12-24
PT73439A (de) 1981-08-01
ES8308877A1 (es) 1983-10-01
ES8308878A1 (es) 1983-10-01
PT73439B (de) 1983-06-20
AU7343981A (en) 1982-02-04
ES514588A0 (es) 1983-10-01
IL63428A0 (en) 1981-10-30
CA1172188A (en) 1984-08-07
NZ197840A (en) 1985-08-30
ES514587A0 (es) 1983-10-01
IL63428A (en) 1984-12-31
GB2085873B (en) 1984-03-21
DK160304C (da) 1991-07-29
ES8400425A1 (es) 1983-11-01
AU548331B2 (en) 1985-12-05
GR74313B (enExample) 1984-06-22
ES504316A0 (es) 1982-12-01
EP0045281B1 (de) 1985-05-08
ES8301476A1 (es) 1982-12-01
DK160304B (da) 1991-02-25

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH

8339 Ceased/non-payment of the annual fee