DE3169235D1 - New 3h-naphtho(1,2-d)imidazoles, the process for preparing them, the compounds for use as antiinflammatory agents and compositions containing them - Google Patents
New 3h-naphtho(1,2-d)imidazoles, the process for preparing them, the compounds for use as antiinflammatory agents and compositions containing themInfo
- Publication number
- DE3169235D1 DE3169235D1 DE8181103678T DE3169235T DE3169235D1 DE 3169235 D1 DE3169235 D1 DE 3169235D1 DE 8181103678 T DE8181103678 T DE 8181103678T DE 3169235 T DE3169235 T DE 3169235T DE 3169235 D1 DE3169235 D1 DE 3169235D1
- Authority
- DE
- Germany
- Prior art keywords
- preparing
- compositions containing
- antiinflammatory agents
- compounds
- naphtho
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HCCNHYWZYYIOFM-UHFFFAOYSA-N 3h-benzo[e]benzimidazole Chemical class C1=CC=C2C(N=CN3)=C3C=CC2=C1 HCCNHYWZYYIOFM-UHFFFAOYSA-N 0.000 title abstract 2
- 229940121363 anti-inflammatory agent Drugs 0.000 title abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Resins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT22601/80A IT1150955B (it) | 1980-06-06 | 1980-06-06 | Derivati 3h-naft(1.2-d)-imidazolici il procedimento per la loro preparazione, il loro uso come agenti antiinfiammatori e le composizioni farmaceutiche che li contengono |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3169235D1 true DE3169235D1 (en) | 1985-04-18 |
Family
ID=11198315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8181103678T Expired DE3169235D1 (en) | 1980-06-06 | 1981-05-13 | New 3h-naphtho(1,2-d)imidazoles, the process for preparing them, the compounds for use as antiinflammatory agents and compositions containing them |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4411907A (forum.php) |
| EP (1) | EP0041630B1 (forum.php) |
| JP (1) | JPS5714577A (forum.php) |
| AT (1) | ATE12106T1 (forum.php) |
| AU (1) | AU538591B2 (forum.php) |
| CA (1) | CA1152993A (forum.php) |
| DE (1) | DE3169235D1 (forum.php) |
| IT (1) | IT1150955B (forum.php) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1582884A (en) * | 1977-05-19 | 1981-01-14 | Beecham Group Ltd | Clavulanic acid derivatives their preparation and use |
| ZA804670B (en) * | 1979-08-03 | 1981-07-29 | Beecham Group Ltd | Derivatives of clavulanic acid, a process for their preparation and their use |
| EP0053893B1 (en) * | 1980-12-09 | 1985-03-20 | Beecham Group Plc | Derivatives of clavulanic acid, their preparation and their use |
| NZ199200A (en) * | 1980-12-23 | 1984-07-31 | Beecham Group Ltd | Clavulanic acid derivatives and pharmaceutical compositions |
| US6858630B2 (en) * | 1999-12-06 | 2005-02-22 | Smithkline Beecham Corporation | Naphthimidazole derivatives and their use as thrombopoietin mimetics |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1484615A (en) * | 1974-11-23 | 1977-09-01 | Lepetit Spa | Tricyclic n-containing derivatives |
| ATE2269T1 (de) * | 1978-12-21 | 1983-02-15 | Gruppo Lepetit S.P.A. | 3h-naphtho(1,2-d)imidazole, verfahren zu deren herstellung, verbindungen zur verwendung als entzuendungshemmende und antimikrobielle mittel und sie enthaltende zusammensetzungen zu dieser verwendung. |
-
1980
- 1980-06-06 IT IT22601/80A patent/IT1150955B/it active
-
1981
- 1981-05-13 EP EP81103678A patent/EP0041630B1/en not_active Expired
- 1981-05-13 AT AT81103678T patent/ATE12106T1/de not_active IP Right Cessation
- 1981-05-13 DE DE8181103678T patent/DE3169235D1/de not_active Expired
- 1981-05-22 US US06/266,228 patent/US4411907A/en not_active Expired - Lifetime
- 1981-06-01 AU AU71233/81A patent/AU538591B2/en not_active Ceased
- 1981-06-05 JP JP8675281A patent/JPS5714577A/ja active Granted
- 1981-06-05 CA CA000379082A patent/CA1152993A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU538591B2 (en) | 1984-08-23 |
| CA1152993A (en) | 1983-08-30 |
| JPS5714577A (en) | 1982-01-25 |
| ATE12106T1 (de) | 1985-03-15 |
| AU7123381A (en) | 1981-12-10 |
| EP0041630B1 (en) | 1985-03-13 |
| US4411907A (en) | 1983-10-25 |
| IT1150955B (it) | 1986-12-17 |
| JPH0346468B2 (forum.php) | 1991-07-16 |
| IT8022601A0 (it) | 1980-06-06 |
| EP0041630A1 (en) | 1981-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |