DE3166731D1 - Bicyclo (3,2,1) octylbenzamides, a process for their preparation and pharmaceutical compositions containing them - Google Patents

Bicyclo (3,2,1) octylbenzamides, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3166731D1
DE3166731D1 DE8181305670T DE3166731T DE3166731D1 DE 3166731 D1 DE3166731 D1 DE 3166731D1 DE 8181305670 T DE8181305670 T DE 8181305670T DE 3166731 T DE3166731 T DE 3166731T DE 3166731 D1 DE3166731 D1 DE 3166731D1
Authority
DE
Germany
Prior art keywords
octylbenzamides
bicyclo
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181305670T
Other languages
English (en)
Inventor
Eric Alfred Watts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE3166731D1 publication Critical patent/DE3166731D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8181305670T 1980-12-12 1981-12-02 Bicyclo (3,2,1) octylbenzamides, a process for their preparation and pharmaceutical compositions containing them Expired DE3166731D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8039823 1980-12-12

Publications (1)

Publication Number Publication Date
DE3166731D1 true DE3166731D1 (en) 1984-11-22

Family

ID=10517932

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181305670T Expired DE3166731D1 (en) 1980-12-12 1981-12-02 Bicyclo (3,2,1) octylbenzamides, a process for their preparation and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (1) US4410535A (de)
EP (1) EP0055524B1 (de)
JP (1) JPS57122084A (de)
AU (1) AU548723B2 (de)
CA (1) CA1167443A (de)
DE (1) DE3166731D1 (de)
DK (1) DK529181A (de)
ES (1) ES8305359A1 (de)
GB (1) GB2091722B (de)
GR (1) GR77332B (de)
IE (1) IE51924B1 (de)
MX (1) MX7052E (de)
NZ (1) NZ199080A (de)
PT (1) PT74090B (de)
ZA (1) ZA818221B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0069482A1 (de) * 1981-06-29 1983-01-12 Beecham Group Plc Azabicycloalkylbenzamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE3368061D1 (en) * 1982-05-11 1987-01-15 Beecham Group Plc Azabicycloalkane derivatives, their preparation and medicaments containing them
GB8317597D0 (en) * 1983-06-29 1983-08-03 Beecham Group Plc Pharmaceutical compounds
US5070094A (en) * 1989-09-05 1991-12-03 G. D. Searle & Co. N-benzyltropaneamides
ES2400875T3 (es) * 2008-04-11 2013-04-15 Janssen Pharmaceutica N.V. Tiazolopiridin-2-iloxi-fenil y tiazolopirazin-2-iloxi-fenil aminas como moduladores de la leucotrieno A4 hidrolasa
NZ596137A (en) 2009-05-14 2013-08-30 Janssen Pharmaceutica Nv Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase
CN103319384A (zh) * 2013-06-18 2013-09-25 苏州诚和医药化学有限公司 制备2-甲氧基-4-氨基-5-乙砜基苯甲酸的方法
CN103304453A (zh) * 2013-06-18 2013-09-18 苏州诚和医药化学有限公司 两步法合成2-甲氧基-4-氨基-5-乙砜基苯甲酸

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593146A (en) * 1976-11-05 1981-07-15 Beecham Group Ltd Octahydro-quinolizinyl benzamide derivatives
FR2415099A1 (fr) * 1978-01-20 1979-08-17 Ile De France Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes
JPS5592384A (en) * 1978-12-30 1980-07-12 Beecham Group Ltd Compound having pharmacological activity
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2476088A2 (fr) * 1979-01-16 1981-08-21 Delalande Sa Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
IL61642A0 (en) * 1979-12-20 1981-01-30 Beecham Group Ltd Aniline derivatives,their preparation and pharmalceutical compositions containing them

Also Published As

Publication number Publication date
PT74090B (en) 1983-05-23
ZA818221B (en) 1982-10-27
JPS57122084A (en) 1982-07-29
EP0055524B1 (de) 1984-10-17
IE812913L (en) 1982-06-12
ES507918A0 (es) 1983-04-01
GB2091722B (en) 1984-09-12
PT74090A (en) 1982-01-01
EP0055524A2 (de) 1982-07-07
AU548723B2 (en) 1986-01-02
DK529181A (da) 1982-06-13
CA1167443A (en) 1984-05-15
NZ199080A (en) 1984-07-31
ES8305359A1 (es) 1983-04-01
EP0055524A3 (en) 1982-09-22
GB2091722A (en) 1982-08-04
US4410535A (en) 1983-10-18
GR77332B (de) 1984-09-11
AU7843881A (en) 1982-06-17
MX7052E (es) 1987-04-08
IE51924B1 (en) 1987-04-29

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee