DE3163675D1 - Extraction of interferon from bacteria - Google Patents

Extraction of interferon from bacteria

Info

Publication number
DE3163675D1
DE3163675D1 DE8181109770T DE3163675T DE3163675D1 DE 3163675 D1 DE3163675 D1 DE 3163675D1 DE 8181109770 T DE8181109770 T DE 8181109770T DE 3163675 T DE3163675 T DE 3163675T DE 3163675 D1 DE3163675 D1 DE 3163675D1
Authority
DE
Germany
Prior art keywords
interferon
bacteria
extraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181109770T
Other languages
English (en)
Inventor
Paul Leibowitz
Marvin J Weinstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE3163675D1 publication Critical patent/DE3163675D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/005—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor after treatment of microbial biomass not covered by C12N1/02 - C12N1/08
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/811—Interferon
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE8181109770T 1980-11-26 1981-11-19 Extraction of interferon from bacteria Expired DE3163675D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21042680A 1980-11-26 1980-11-26
US06/221,135 US4315852A (en) 1980-11-26 1980-12-29 Extraction of interferon from bacteria

Publications (1)

Publication Number Publication Date
DE3163675D1 true DE3163675D1 (en) 1984-06-20

Family

ID=26905139

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181109770T Expired DE3163675D1 (en) 1980-11-26 1981-11-19 Extraction of interferon from bacteria

Country Status (9)

Country Link
US (1) US4315852A (de)
EP (1) EP0052861B1 (de)
CA (1) CA1176980A (de)
DE (1) DE3163675D1 (de)
DK (1) DK158475C (de)
FI (1) FI70927C (de)
HK (1) HK14187A (de)
IE (1) IE51858B1 (de)
IL (1) IL64385A (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62552A0 (en) 1980-04-03 1981-06-29 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
US4450103A (en) * 1982-03-01 1984-05-22 Cetus Corporation Process for recovering human IFN-β from a transformed microorganism
US4925919A (en) * 1984-04-25 1990-05-15 Roland Mertelsmann Purified interleukin 2
US4462940A (en) * 1982-09-23 1984-07-31 Cetus Corporation Process for the recovery of human β-interferon-like polypeptides
US5702699A (en) * 1982-09-23 1997-12-30 Cetus Corporation Process for the recovery of lipophilic proteins
US4992271A (en) * 1982-09-23 1991-02-12 Cetus Corporation Formulation for lipophilic IL-2 proteins
US4853332A (en) * 1982-10-19 1989-08-01 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of biologically active proteins
JP2551746B2 (ja) * 1983-07-19 1996-11-06 サントリー株式会社 改良プラスミドベクタ−およびその利用
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
US4908433A (en) * 1984-04-25 1990-03-13 Sloan-Kettering Institute For Cancer Research Uses of interleukin-2
US4908434A (en) * 1984-04-25 1990-03-13 Sloan-Kettering Institute For Cancer Research Process for preparing purified interleukin-2
DE3432196A1 (de) * 1984-09-01 1986-03-06 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neues mechanisches aufschlussverfahren von bakterienzellen zur isolierung von rekombinant hergestellten peptiden
US4675387A (en) * 1985-07-26 1987-06-23 E. I. Du Pont De Nemours And Company Method for extracting protein with organic acid
AU636043B2 (en) * 1990-06-04 1993-04-08 Schering Corporation Method for preparing interferon alpha-2 crystals
US5441734A (en) * 1993-02-25 1995-08-15 Schering Corporation Metal-interferon-alpha crystals
US6399296B1 (en) * 1994-07-20 2002-06-04 The General Hospital Corporation Interaction trap systems for detecting protein interactions
US6281337B1 (en) 1998-11-12 2001-08-28 Schering Corporation Methods for conversion of protein isoforms
CZ303110B6 (cs) 1998-11-12 2012-04-04 Schering Corporation Zpusob zvýšení výtežku prostredku obsahujícího interferon alfa
UY27373A1 (es) * 2001-07-09 2003-02-28 Schering Ag Formulaciones de interferón beta-humano
GB0319601D0 (en) 2003-08-20 2003-09-24 Sandoz Ag Production process
HUE052976T2 (hu) 2005-04-11 2021-06-28 Horizon Pharma Rheumatology Llc Urát-oxidáz variáns formái és azok alkalmazása
PL2013225T3 (pl) * 2006-04-12 2015-06-30 Crealta Pharmaceuticals Llc Oczyszczanie białek z zastosowaniem kationowego środka powierzchniowo czynnego
US20110257368A1 (en) 2008-12-23 2011-10-20 Schering Corporation Purification of recombinantly produced interferon
MX347903B (es) 2009-06-25 2017-05-18 Crealta Pharmaceuticals Llc Metodos y equipos para predecir el riesgo de reaccion a la infusion y perdida de respuesta mediada por anticuerpos al supervisar el acido urico en suero durante una terapia con uricasa conjugada con peg.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3699222A (en) * 1958-03-11 1972-10-17 Nat Res Dev Production of viral interfering substances
GB980227A (en) * 1962-08-16 1965-01-13 Glaxo Lab Ltd Purification and/or concentration of material containing interferon
GB1055896A (en) * 1963-12-10 1967-01-18 Glaxo Lab Ltd Silica adsorbents in interferon purification and/or concentration
US3256152A (en) * 1965-06-14 1966-06-14 Merck & Co Inc Concentration and purification of interferons, viral inhibiting substances (vis), viral inhibiting factors (vif), or viral inhibitory material
DE2961658D1 (en) * 1978-05-17 1982-02-18 Thomae Gmbh Dr K Process for preparing human interferon
US4262090A (en) * 1979-06-04 1981-04-14 Cetus Corporation Interferon production

Also Published As

Publication number Publication date
EP0052861A3 (en) 1983-01-26
DK158475C (da) 1990-10-15
HK14187A (en) 1987-02-27
FI70927B (fi) 1986-07-18
US4315852A (en) 1982-02-16
DK523881A (da) 1982-05-27
IE51858B1 (en) 1987-04-15
IE812767L (en) 1982-05-26
IL64385A0 (en) 1982-02-28
EP0052861A2 (de) 1982-06-02
EP0052861B1 (de) 1984-05-16
CA1176980A (en) 1984-10-30
FI813785L (fi) 1982-05-27
DK158475B (da) 1990-05-21
FI70927C (fi) 1986-10-27
IL64385A (en) 1984-09-30

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