DE3162388D1 - 2-aminotetralin compounds and pharmaceutical compositions having central alpha1 agonist activity - Google Patents

2-aminotetralin compounds and pharmaceutical compositions having central alpha1 agonist activity

Info

Publication number
DE3162388D1
DE3162388D1 DE8181304726T DE3162388T DE3162388D1 DE 3162388 D1 DE3162388 D1 DE 3162388D1 DE 8181304726 T DE8181304726 T DE 8181304726T DE 3162388 T DE3162388 T DE 3162388T DE 3162388 D1 DE3162388 D1 DE 3162388D1
Authority
DE
Germany
Prior art keywords
central
pharmaceutical compositions
agonist activity
alpha1
aminotetralin compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181304726T
Other languages
English (en)
Inventor
Robert Michael Demarinis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of DE3162388D1 publication Critical patent/DE3162388D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8181304726T 1980-11-24 1981-10-12 2-aminotetralin compounds and pharmaceutical compositions having central alpha1 agonist activity Expired DE3162388D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/210,470 US4320148A (en) 1980-11-24 1980-11-24 2-Aminotetralin compounds, pharmaceutical compositions and method of producing central alpha1 agonist activity

Publications (1)

Publication Number Publication Date
DE3162388D1 true DE3162388D1 (en) 1984-03-29

Family

ID=22783029

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181304726T Expired DE3162388D1 (en) 1980-11-24 1981-10-12 2-aminotetralin compounds and pharmaceutical compositions having central alpha1 agonist activity

Country Status (4)

Country Link
US (1) US4320148A (de)
EP (1) EP0052932B1 (de)
AT (1) ATE6358T1 (de)
DE (1) DE3162388D1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2512814A1 (fr) * 1981-09-16 1983-03-18 Synthelabo Derives d'amino-2 tetrahydro-1,2,3,4 naphtalene, leur preparation et leur application en therapeutique
US4456725A (en) * 1982-12-20 1984-06-26 General Electric Company Compositions comprising polycarbonates, acrylate resins, and aliphatic hydrocarbons
DE3832571A1 (de) * 1988-09-24 1990-05-31 Boehringer Ingelheim Kg Verwendung von 2,7-diamino-1,2,3,4-tetrahydronaphthalinen als arzneimittel, neue 2,7-diamino-1,2,3,4-tetrahydronaphthaline sowie verfahren zu ihrer herstellung
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins
ATE113271T1 (de) * 1989-01-09 1994-11-15 Upjohn Co Halogensubstituierte aminotetraline.
ZA901277B (en) * 1989-02-27 1991-10-30 Lilly Co Eli Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes
US5151446A (en) * 1989-09-25 1992-09-29 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
US5071875A (en) * 1989-09-25 1991-12-10 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
US5807897A (en) * 1996-03-01 1998-09-15 Zeneca Limited Aminotetralin derivative and compositions and method of use thereof
US6503935B1 (en) 1998-08-07 2003-01-07 Abbott Laboratories Imidazoles and related compounds as α1A agonists
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
DE10334188B4 (de) * 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
DE10334187A1 (de) * 2003-07-26 2005-03-03 Schwarz Pharma Ag Substituierte 2-Aminotetraline zur Behandlung von Depressionen
EP2215072B1 (de) * 2007-11-28 2015-09-02 UCB Pharma GmbH Polymorphe rotigotin-form

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3253037A (en) * 1962-06-19 1966-05-24 Ciba Geigy Corp N-2-alkynyl-amino-benzocylo-alkanes
US3637740A (en) * 1969-04-21 1972-01-25 Pfizer Aminobenzocycloalkane compounds
US4096173A (en) * 1977-03-28 1978-06-20 Eli Lilly And Company Chlorinated 1-aminoindane N-methyl transferase inhibitors

Also Published As

Publication number Publication date
EP0052932A1 (de) 1982-06-02
EP0052932B1 (de) 1984-02-22
ATE6358T1 (de) 1984-03-15
US4320148A (en) 1982-03-16

Similar Documents

Publication Publication Date Title
DE3069944D1 (en) Chloro- and alkoxy-substituted-2,4-diaminoquinazolines and pharmaceutical compositions containing them
IL56581A (en) 6-substituted-8-(methoxymethyl)or(methylmercaptomethyl)ergolines and ergolenes,their preparation and pharmaceutical compositions containing them
MX9203176A (es) 1,2,4-triazolonas substituidas con fenoxietilo y composiciones farmaceuticas que las contienen.
DE3162388D1 (en) 2-aminotetralin compounds and pharmaceutical compositions having central alpha1 agonist activity
MX9202623A (es) Compuestos de indol y composiciones farmaceuticas que los contienen.
DE3381822D1 (de) Gnrh-agonisten.
ES8203375A1 (es) Procedimiento de preparar triazoloquinoxalin-4-onas substi- tuidas antihipertensoras
IT8322309V0 (it) Cerniera per mobili.
ZA818737B (en) New tri-tetra-and penta-peptides,their preparation and compositions containing them.
ES247530Y (es) Dispositivo para la confeccion de ensambles modulares pris- maticos.
IL64266A (en) Tetra-substituted benzene compounds,their preparation and pharmaceutical compositions containing them
FI821167A0 (fi) Lokalt anvaendbara farmaceutiska kompositioner, som innehaoller antiinflammatoriska steroider
FI822386L (fi) Indol-tromboxansyntetas-inhibitorer, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska kompositioner
MX9203628A (es) Compuestos florados de benciltriazol y composiciones farmaceuticas que los contienen.
BR8301838A (pt) Composicao antioxidante hidroliticamente estavel
DK504283D0 (da) Baerer for flere genstande
KR880013918A (ko) 치환된 니트로알켄, 이의 제조방법 및 이를 함유하는 살충제 조성물
IL85189A (en) Beta-alkyl substituted melatonins,their preparation and pharmaceutical compositions containing them
AU2592988A (en) Novel beta-adrenergic agonists
IL62060A (en) Pharmaceutical and detergent antirhinovirus compositions containing substituted phenoxy(or phenylthio)alkanol derivatives,some new such compounds and their preparation
PT94011A (pt) Processo para a preparacao de 8 alfa- acilamino-ergolinas e de composicoes farmaceuticas que as contem
DE3168544D1 (en) 6,7,8,9-tetrahydro-3h-benz(e)indolamine derivatives, processes for their preparation and intermediates used therein, and pharmaceutical compositions containing the indolamine derivatives
ES267634Y (es) "funda para prendas de vestir".
IL62115A (en) Indane derivatives,their preparation and pharmaceutical compositions containing them
NO985079L (no) Eksplosiv formulering

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee