DE3161869D1 - A pharmaceutical composition for treating hypertension containing l-alpha-methyl-3,4-dihydroxyphenylalanine and salicylamide - Google Patents

A pharmaceutical composition for treating hypertension containing l-alpha-methyl-3,4-dihydroxyphenylalanine and salicylamide

Info

Publication number
DE3161869D1
DE3161869D1 DE8181102809T DE3161869T DE3161869D1 DE 3161869 D1 DE3161869 D1 DE 3161869D1 DE 8181102809 T DE8181102809 T DE 8181102809T DE 3161869 T DE3161869 T DE 3161869T DE 3161869 D1 DE3161869 D1 DE 3161869D1
Authority
DE
Germany
Prior art keywords
dihydroxyphenylalanine
salicylamide
alpha
methyl
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181102809T
Other languages
German (de)
English (en)
Inventor
Stanley Vickers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3161869D1 publication Critical patent/DE3161869D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8181102809T 1980-04-14 1981-04-13 A pharmaceutical composition for treating hypertension containing l-alpha-methyl-3,4-dihydroxyphenylalanine and salicylamide Expired DE3161869D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/139,913 US4321264A (en) 1980-04-14 1980-04-14 α-methyldopa compositions

Publications (1)

Publication Number Publication Date
DE3161869D1 true DE3161869D1 (en) 1984-02-16

Family

ID=22488861

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181102809T Expired DE3161869D1 (en) 1980-04-14 1981-04-13 A pharmaceutical composition for treating hypertension containing l-alpha-methyl-3,4-dihydroxyphenylalanine and salicylamide

Country Status (8)

Country Link
US (1) US4321264A (OSRAM)
EP (1) EP0038060B1 (OSRAM)
JP (1) JPS56161326A (OSRAM)
AT (1) ATE5796T1 (OSRAM)
DE (1) DE3161869D1 (OSRAM)
GR (1) GR74873B (OSRAM)
IE (1) IE51805B1 (OSRAM)
PT (1) PT72802B (OSRAM)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6021570B2 (ja) * 1978-07-04 1985-05-28 三共株式会社 ド−パ類の高濃度製剤の製法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL263355A (OSRAM) * 1960-04-08
US3526698A (en) * 1968-04-11 1970-09-01 Merck & Co Inc Stabilization of levo-3-(3,4-dihydroxyphenyl)-2-methylalanine with sodium bisulfite and sorbitol
US3574834A (en) * 1969-04-30 1971-04-13 Merck & Co Inc Medicinal soporific composition
IE36780B1 (en) * 1971-11-11 1977-02-16 Ciba Geigy Ag New pharmaceutical preparations
IE49218B1 (en) * 1978-12-01 1985-08-21 Merck & Co Inc Methyldopa composition

Also Published As

Publication number Publication date
US4321264A (en) 1982-03-23
GR74873B (OSRAM) 1984-07-12
PT72802B (en) 1983-03-29
IE51805B1 (en) 1987-04-01
ATE5796T1 (de) 1984-01-15
EP0038060A1 (en) 1981-10-21
EP0038060B1 (en) 1984-01-11
IE810819L (en) 1981-10-14
JPS56161326A (en) 1981-12-11
PT72802A (en) 1981-05-01

Similar Documents

Publication Publication Date Title
IE801178L (en) 4-substituted-3-hydroxy-3-pyrroline-2,5-diones.
GB2110932A (en) Method and composition for treating acne
JPS5251327A (en) 3-trihydroxygermylpropionic acid and its salts and process for prepari ng the same
EP0114878A4 (en) PHTHALAZINE SUBSTITUTED AMINOMETHYLBENZOLE COMBS, COMPOSITIONS AND USE.
ES508202A0 (es) "procedimiento de tratamiento de vegetales".
JPS53105477A (en) 7-glycylprolylamono-4-methylcoumarine
AU5385479A (en) Cyanamides
IT7926662A0 (it) Composizione farmaceutica contenente 3,4-di-idro-3-osso-2-chinossaline.
AU7135881A (en) Indene-3-acetic, acid composition for relieving or preventing adiabetic complication
GR74873B (OSRAM)
ES510032A0 (es) "planta depuradora de aguas residuales en especial para la depuracion de alpechines o jamilas".
JPS525969A (en) Sewage disposal method
ES8404183A1 (es) Un procedimiento para la preparacion de composiciones farmaceuticas orales de acido propionhidroxamico.
AU532823B2 (en) Aspirin + heptaminol composition
JPS5231925A (en) Contact chip
JPS53124201A (en) 6-ethyl-substituted higher alkane and its use
JPS549271A (en) 3',4'-methylenedioxyphenylbutanal
FI834704A7 (fi) Uudet karboksamidoguanidiinit, menetelmä niiden aikaansaamiseksi ja ni itä sisältävät lääkekoostumukset.
IT8222611A0 (it) Composizione farmaceutica disintossicante.
JPS52124031A (en) Adhesives
JPS5234924A (en) Miticides
FI77023B (fi) Foerfarande foer framstaellning av 1-alkyl- eller 1,4-dialkyl-1h-pyrrol-2-aettiksyraestrar.
JPS5210421A (en) A thiadiazoline series germicide
JPS52142086A (en) Thiol carbamates and herbicides containing the same
ES264730Y (es) "juego de composicion, perfeccionado".

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee