DE3070534D1 - Pharmacologically active amine-carboxyboranes - Google Patents

Pharmacologically active amine-carboxyboranes

Info

Publication number
DE3070534D1
DE3070534D1 DE8080810406T DE3070534T DE3070534D1 DE 3070534 D1 DE3070534 D1 DE 3070534D1 DE 8080810406 T DE8080810406 T DE 8080810406T DE 3070534 T DE3070534 T DE 3070534T DE 3070534 D1 DE3070534 D1 DE 3070534D1
Authority
DE
Germany
Prior art keywords
carboxyboranes
pharmacologically active
active amine
amine
r1r2nhbh2c
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080810406T
Other languages
German (de)
English (en)
Inventor
Bernard F Spielvogel
Andrew T Mcphail
Iris H Hall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Application granted granted Critical
Publication of DE3070534D1 publication Critical patent/DE3070534D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/027—Organoboranes and organoborohydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8080810406T 1979-12-21 1980-12-19 Pharmacologically active amine-carboxyboranes Expired DE3070534D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10641679A 1979-12-21 1979-12-21

Publications (1)

Publication Number Publication Date
DE3070534D1 true DE3070534D1 (en) 1985-05-23

Family

ID=22311304

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080810406T Expired DE3070534D1 (en) 1979-12-21 1980-12-19 Pharmacologically active amine-carboxyboranes

Country Status (4)

Country Link
EP (1) EP0034238B1 (online.php)
JP (1) JPS57145886A (online.php)
AT (1) ATE12774T1 (online.php)
DE (1) DE3070534D1 (online.php)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6299384A (ja) * 1984-10-25 1987-05-08 デユ−ク・ユニヴア−シテイ （ｃｈ↓３）↓３ｎｂｈ↓２ｃｏｏｃｈ↓３を含む脂血低下剤
US4647555A (en) * 1984-10-25 1987-03-03 The United States Of America As Represented By The Secretary Of The Army Esters of boron analogues of amino acids
US4740504A (en) * 1985-10-08 1988-04-26 United States Borax & Chemical Corp. Antihyperlipidemic amine boranes
US4672060A (en) * 1985-10-18 1987-06-09 United States Borax & Chemical Corporation Antihyperlipidemic ammonium polyboranes
US4977268A (en) * 1988-04-08 1990-12-11 Duke University Boron dipeptide compounds
US5023513A (en) * 1989-06-09 1991-06-11 Boron Biologicals, Inc. Amine-alkylborane derivatives and methods
US5143907A (en) * 1991-05-10 1992-09-01 Boron Biologicals, Inc. Phosphite-borane compounds, and method of making and using the same
US5260427A (en) * 1991-05-10 1993-11-09 Boron Biolgicals, Inc. Nucleosidylphosphite-borane compounds and method of making the same
HU226659B1 (en) * 1999-10-05 2009-06-29 Mallinckrodt Inc Carbon monoxide source for preparation of transition-metal-carbonyl-complexes
GB0111872D0 (en) 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
EP2042181A1 (en) 2002-02-04 2009-04-01 ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
US7968605B2 (en) 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
WO2007032004A1 (en) * 2005-09-13 2007-03-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of amine-borane compounds as anti-microbial agents
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
US9163044B2 (en) 2011-04-19 2015-10-20 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
WO2013013179A1 (en) 2011-07-21 2013-01-24 Alfama, Inc. Ruthenium carbon monoxide releasing molecules and uses thereof

Also Published As

Publication number Publication date
EP0034238B1 (en) 1985-04-17
EP0034238A1 (en) 1981-08-26
JPS6228954B2 (online.php) 1987-06-23
ATE12774T1 (de) 1985-05-15
JPS57145886A (en) 1982-09-09

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee