DE3068250D1 - 3-hydroxymethyldibenzo(b,f)thiepins and dibenzo(b,f)thiepin-3-carboxaldehydes as prostaglandin antagonists, process for their preparation and pharmaceutical compositions - Google Patents

3-hydroxymethyldibenzo(b,f)thiepins and dibenzo(b,f)thiepin-3-carboxaldehydes as prostaglandin antagonists, process for their preparation and pharmaceutical compositions

Info

Publication number
DE3068250D1
DE3068250D1 DE8080107205T DE3068250T DE3068250D1 DE 3068250 D1 DE3068250 D1 DE 3068250D1 DE 8080107205 T DE8080107205 T DE 8080107205T DE 3068250 T DE3068250 T DE 3068250T DE 3068250 D1 DE3068250 D1 DE 3068250D1
Authority
DE
Germany
Prior art keywords
hydroxymethyldibenzo
thiepins
carboxaldehydes
thiepin
dibenzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080107205T
Other languages
German (de)
English (en)
Inventor
Pierre A Hamel
Joshua A Rokach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Merck Sharp and Dohme IA Corp
Original Assignee
Merck Sharp and Dohme Ltd
Merck Sharp and Dohme IA Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/097,755 external-priority patent/US4237160A/en
Application filed by Merck Sharp and Dohme Ltd, Merck Sharp and Dohme IA Corp filed Critical Merck Sharp and Dohme Ltd
Application granted granted Critical
Publication of DE3068250D1 publication Critical patent/DE3068250D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DE8080107205T 1979-11-27 1980-11-20 3-hydroxymethyldibenzo(b,f)thiepins and dibenzo(b,f)thiepin-3-carboxaldehydes as prostaglandin antagonists, process for their preparation and pharmaceutical compositions Expired DE3068250D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9775979A 1979-11-27 1979-11-27
US06/097,755 US4237160A (en) 1979-11-27 1979-11-27 3-Hydroxymethyldibenzo[b,f]thiepins as prostaglandin antagonists

Publications (1)

Publication Number Publication Date
DE3068250D1 true DE3068250D1 (en) 1984-07-19

Family

ID=26793604

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080107205T Expired DE3068250D1 (en) 1979-11-27 1980-11-20 3-hydroxymethyldibenzo(b,f)thiepins and dibenzo(b,f)thiepin-3-carboxaldehydes as prostaglandin antagonists, process for their preparation and pharmaceutical compositions

Country Status (7)

Country Link
EP (1) EP0029587B1 (OSRAM)
DE (1) DE3068250D1 (OSRAM)
DK (1) DK502780A (OSRAM)
ES (1) ES497132A0 (OSRAM)
GR (1) GR71609B (OSRAM)
IE (1) IE50572B1 (OSRAM)
PT (1) PT72111B (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535171A (en) * 1982-11-18 1985-08-13 Merck Frosst Canada, Inc. Dibenzo[b,f]thiepin-3-carboxaldehydes as prostaglandin antagonists
US4622403A (en) * 1983-10-11 1986-11-11 Merck Frosst Canada, Inc. 6-H dibenz[b,f]thiepin compounds
US4663307A (en) * 1983-10-26 1987-05-05 Merck Frosst Canada, Inc. Anti-allergic and anti-thromboembolic 6H-dibenz-[b,e][1,4]-oxathiepin derivatives, compositions, and method of use therefor
US5334628A (en) * 1984-06-09 1994-08-02 Kaken Pharmaceutical Co., Ltd. Amine derivatives, processes for preparing the same and fungicides containing the same
EP0805155B1 (en) * 1994-09-28 2002-03-13 Nippon Suisan Kaisha, Ltd. Novel antioxidant tricyclic fused heterocyclic compound
WO2002056995A1 (en) * 2001-01-18 2002-07-25 Nicholas Jackson Water filter

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205170A (en) * 1976-12-03 1980-05-27 Nippon Chemiphar Company, Limited Propionic acid derivatives
PT68303A (en) * 1977-07-26 1978-08-01 Merck & Co Inc Process for the preparation of dibenzo/b,f/thiepin
IT7850376A0 (it) * 1977-07-26 1978-07-19 Merck & Co Inc Composizioni di dibenzo(b.f)tiepina e procedimento per la loro preparazione

Also Published As

Publication number Publication date
PT72111B (en) 1982-06-25
EP0029587A1 (en) 1981-06-03
PT72111A (en) 1980-12-01
DK502780A (da) 1981-05-28
ES8300742A1 (es) 1982-11-16
IE802455L (en) 1981-05-27
ES497132A0 (es) 1982-11-16
EP0029587B1 (en) 1984-06-13
GR71609B (OSRAM) 1983-06-17
IE50572B1 (en) 1986-05-14

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee