DE3065428D1 - Derivative of creatinol-o-phosphate having therapeutical action, process for the preparation thereof and related pharmaceutical compositions - Google Patents
Derivative of creatinol-o-phosphate having therapeutical action, process for the preparation thereof and related pharmaceutical compositionsInfo
- Publication number
- DE3065428D1 DE3065428D1 DE8080106293T DE3065428T DE3065428D1 DE 3065428 D1 DE3065428 D1 DE 3065428D1 DE 8080106293 T DE8080106293 T DE 8080106293T DE 3065428 T DE3065428 T DE 3065428T DE 3065428 D1 DE3065428 D1 DE 3065428D1
- Authority
- DE
- Germany
- Prior art keywords
- creatinol
- phosphate
- preparation
- derivative
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FOIPWTMKYXWFGC-UHFFFAOYSA-N creatinolfosfate Chemical class NC(=N)N(C)CCOP(O)(O)=O FOIPWTMKYXWFGC-UHFFFAOYSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 159000000003 magnesium salts Chemical class 0.000 abstract 3
- 206010061216 Infarction Diseases 0.000 abstract 1
- 230000007574 infarction Effects 0.000 abstract 1
- 150000002681 magnesium compounds Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT26854/79A IT1124697B (it) | 1979-10-26 | 1979-10-26 | Derivati di creatinolo o-fosfato ad azione terapeutica,procedimento per la sua preparazione e relativ-e composizioni farmaceutiche |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3065428D1 true DE3065428D1 (en) | 1983-12-01 |
Family
ID=11220382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8080106293T Expired DE3065428D1 (en) | 1979-10-26 | 1980-10-16 | Derivative of creatinol-o-phosphate having therapeutical action, process for the preparation thereof and related pharmaceutical compositions |
Country Status (6)
Country | Link |
---|---|
US (1) | US4376117A (de) |
EP (1) | EP0028336B1 (de) |
JP (1) | JPS5673089A (de) |
AT (1) | ATE5145T1 (de) |
DE (1) | DE3065428D1 (de) |
IT (1) | IT1124697B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63126755U (de) * | 1987-02-06 | 1988-08-18 | ||
US5108365A (en) * | 1990-06-20 | 1992-04-28 | Woods Jr Walter T | Transluminal infusion of magnesium during coronary angioplasty |
IT1306173B1 (it) * | 1999-07-23 | 2001-05-30 | Sigma Tau Healthscience Spa | Composizione per la prevenzione degli affaticamenti muscolari e permigliorare il rendimento energetico muscolare. |
WO2006034586A1 (en) * | 2004-09-29 | 2006-04-06 | Aplodan Formulations Ltd. | Nutritional composition for promoting muscle performance and acting as hydrogen (h+) blocker |
US7375097B2 (en) * | 2006-08-30 | 2008-05-20 | Aplodan Formulations Ltd. | Increasing ATP availability by inhibition of creatine kinase (CK) leakage resulting from high-intensity exercise |
US7368441B2 (en) * | 2006-08-30 | 2008-05-06 | Aplodan Formulations Ltd. | Method of increasing intracellular concentrations of phosphate and increasing the force of muscular contractions |
US8372821B2 (en) | 2008-04-09 | 2013-02-12 | Jack H. Owoc | Stable aqueous compositions comprising bioactive creatine species |
CN101671282B (zh) * | 2009-10-16 | 2012-12-19 | 天津天成制药有限公司 | 肌肉醇硫酸盐的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR6401E (fr) | 1906-01-12 | 1906-11-03 | Farbenfab Vorm Bayer F & Co | Production de produits de substitution mono-iodés d'acides gras supérieurs |
US3016399A (en) * | 1959-05-27 | 1962-01-09 | Fr De Rech S Biochimiques H Be | Cholinphosphoric acid salts and production thereof |
FR6401M (de) * | 1966-11-14 | 1968-10-21 | ||
US4039636A (en) * | 1973-06-28 | 1977-08-02 | The Dow Chemical Company | Magnesium dialkyl phosphates and their preparation |
-
1979
- 1979-10-26 IT IT26854/79A patent/IT1124697B/it active
-
1980
- 1980-10-16 DE DE8080106293T patent/DE3065428D1/de not_active Expired
- 1980-10-16 AT AT80106293T patent/ATE5145T1/de not_active IP Right Cessation
- 1980-10-16 EP EP80106293A patent/EP0028336B1/de not_active Expired
- 1980-10-17 US US06/198,263 patent/US4376117A/en not_active Expired - Lifetime
- 1980-10-24 JP JP14825680A patent/JPS5673089A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5673089A (en) | 1981-06-17 |
JPS616079B2 (de) | 1986-02-24 |
EP0028336A1 (de) | 1981-05-13 |
EP0028336B1 (de) | 1983-10-26 |
US4376117A (en) | 1983-03-08 |
IT1124697B (it) | 1986-05-14 |
ATE5145T1 (de) | 1983-11-15 |
IT7926854A0 (it) | 1979-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: ZAMBON GROUP S.P.A., VICENZA, IT |
|
8328 | Change in the person/name/address of the agent |
Free format text: DANNENBERG, G., DIPL.-ING., 6000 FRANKFURT WEINHOLD, P., DIPL.-CHEM. DR., 8000 MUENCHEN GUDEL, D., DR.PHIL. SCHUBERT, S., DIPL.-ING., 6000 FRANKFURT BARZ, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 8000 MUENCHEN |
|
8339 | Ceased/non-payment of the annual fee |