DE3062097D1 - Pyridazin (2h)-3-ones, process for their preparation and their use in antihypertensive agents - Google Patents

Pyridazin (2h)-3-ones, process for their preparation and their use in antihypertensive agents

Info

Publication number
DE3062097D1
DE3062097D1 DE8080300391T DE3062097T DE3062097D1 DE 3062097 D1 DE3062097 D1 DE 3062097D1 DE 8080300391 T DE8080300391 T DE 8080300391T DE 3062097 T DE3062097 T DE 3062097T DE 3062097 D1 DE3062097 D1 DE 3062097D1
Authority
DE
Germany
Prior art keywords
pyridazin
ones
preparation
antihypertensive agents
antihypertensive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080300391T
Other languages
German (de)
English (en)
Inventor
Larry J Powers
Zavin S Ariyan
Russell Buchman
James A Scozzie
Robert E Moser
William J Pyne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SDS Biotech Corp
Original Assignee
Diamond Shamrock Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diamond Shamrock Corp filed Critical Diamond Shamrock Corp
Application granted granted Critical
Publication of DE3062097D1 publication Critical patent/DE3062097D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/18—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22—Nitrogen and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8080300391T 1979-02-12 1980-02-11 Pyridazin (2h)-3-ones, process for their preparation and their use in antihypertensive agents Expired DE3062097D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/011,416 US4238490A (en) 1979-02-12 1979-02-12 Antihypertensive pyridazin(2H)-3-ones

Publications (1)

Publication Number Publication Date
DE3062097D1 true DE3062097D1 (en) 1983-03-31

Family

ID=21750288

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080300391T Expired DE3062097D1 (en) 1979-02-12 1980-02-11 Pyridazin (2h)-3-ones, process for their preparation and their use in antihypertensive agents

Country Status (11)

Country Link
US (1) US4238490A (en:Method)
EP (1) EP0018063B1 (en:Method)
JP (1) JPS55111473A (en:Method)
AU (1) AU530470B2 (en:Method)
CA (1) CA1142920A (en:Method)
DE (1) DE3062097D1 (en:Method)
DK (1) DK58680A (en:Method)
IE (1) IE49390B1 (en:Method)
IL (1) IL59356A (en:Method)
NZ (1) NZ192845A (en:Method)
ZA (1) ZA80776B (en:Method)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982000402A1 (en) * 1980-08-07 1982-02-18 Shamrock Corp Diamond Herbicidal and plant growth regulant diphenylpyridazinones
US4545810A (en) * 1980-08-07 1985-10-08 Sds Biotech Corporation Herbicidal and plant growth regulant diphenylpyridazinones
WO1983000863A1 (en) * 1981-09-11 1983-03-17 Diamond Shamrock Corp Antiinflammatory and analgetic 4-pyridylpyridazin(2h)-3-ones
FR2648135B1 (fr) * 1989-06-07 1991-09-27 Pf Medicament Derives de phenyl-1-dihydro-1,4 amino-3 oxo-4 pyridazines, leur preparation et leur application en therapeutique
US5189163A (en) * 1989-08-30 1993-02-23 Imperial Chemical Industries Plc Method of preparing pyridazinone derivatives
US4992439A (en) * 1990-02-13 1991-02-12 Bristol-Myers Squibb Company Pyridazine carboxylic acids and esters
US6307047B1 (en) * 1997-08-22 2001-10-23 Abbott Laboratories Prostaglandin endoperoxide H synthase biosynthesis inhibitors
CZ300847B6 (cs) * 1997-08-22 2009-08-26 Abbott Laboratories Arylpyridazinony jako inhibitory biosyntézy prostaglandin endoperoxid H synthasy, jejich použití a farmaceutická kompozice s jejich obsahem
DE69926903T2 (de) * 1998-10-27 2006-07-13 Abbott Laboratories, Abbott Park Prostaglandin endoperoxyde h synthase biosynthese inhibitoren
JP2000247959A (ja) * 1999-02-26 2000-09-12 Kowa Co ピリダジン−３−オン誘導体及びこれを含有する医薬
CN102164485A (zh) * 2008-09-24 2011-08-24 纳幕尔杜邦公司 杀真菌哒嗪

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE528490A (en:Method) *
GB1402511A (en) * 1972-04-15 1975-08-13 Konishiroku Photo Ind Pyridone and pyridazone photographic yellow couplers

Also Published As

Publication number Publication date
JPS6159626B2 (en:Method) 1986-12-17
IE800253L (en) 1980-08-12
IL59356A0 (en) 1980-05-30
IL59356A (en) 1984-05-31
CA1142920A (en) 1983-03-15
DK58680A (da) 1980-08-13
AU5540480A (en) 1980-08-21
IE49390B1 (en) 1985-10-02
EP0018063B1 (en) 1983-02-23
NZ192845A (en) 1984-10-19
ZA80776B (en) 1981-02-25
US4238490A (en) 1980-12-09
AU530470B2 (en) 1983-07-14
JPS55111473A (en) 1980-08-28
EP0018063A1 (en) 1980-10-29

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SDS BIOTECH CORP., PAINESVILLE, OHIO, US

8339 Ceased/non-payment of the annual fee