DE2966199D1 - 6,7-cycloalkano-1,4-oxazepines, process for their preparation and medicines containing them - Google Patents

6,7-cycloalkano-1,4-oxazepines, process for their preparation and medicines containing them

Info

Publication number
DE2966199D1
DE2966199D1 DE7979104083T DE2966199T DE2966199D1 DE 2966199 D1 DE2966199 D1 DE 2966199D1 DE 7979104083 T DE7979104083 T DE 7979104083T DE 2966199 T DE2966199 T DE 2966199T DE 2966199 D1 DE2966199 D1 DE 2966199D1
Authority
DE
Germany
Prior art keywords
pct
cycloalkano
oxazepines
preparation
date
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979104083T
Other languages
German (de)
Inventor
Hans Joerg Dr Treiber
Dieter Dr Lenke
Wolfgang Dr Worstmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Priority to DE7979104083T priority Critical patent/DE2966199D1/en
Application granted granted Critical
Publication of DE2966199D1 publication Critical patent/DE2966199D1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Abstract

PCT No. PCT/EP79/00080 Sec. 371 Date Jun. 26, 1980 Sec. 102(e) Date Jun. 16, 1980 PCT Filed Oct. 22, 1979 PCT Pub. No. WO80/00838 PCT Pub. Date May 1, 1980. The invention relates to novel 1,4-cycloalkano-oxazepines of the general formula <IMAGE> where R1 is hydrogen, hydroxyl or alkoxy or acyloxy of 1 to 4 carbon atoms, R2 is a hydrocarbon radical of 1 to 3 carbon atoms, n is 1, 2 or 3 and x is 0 or 1, and of its salts with physiologically acceptable acids; processes for their preparation, and their use in therapy. The novel substances are suitable for the pharmacotherapy of pains of various origins.
DE7979104083T 1978-10-26 1979-10-22 6,7-cycloalkano-1,4-oxazepines, process for their preparation and medicines containing them Expired DE2966199D1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE7979104083T DE2966199D1 (en) 1978-10-26 1979-10-22 6,7-cycloalkano-1,4-oxazepines, process for their preparation and medicines containing them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782846567 DE2846567A1 (en) 1978-10-26 1978-10-26 NEW 1,4-CYCLOALKANOOXAZEPINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME
DE7979104083T DE2966199D1 (en) 1978-10-26 1979-10-22 6,7-cycloalkano-1,4-oxazepines, process for their preparation and medicines containing them

Publications (1)

Publication Number Publication Date
DE2966199D1 true DE2966199D1 (en) 1983-11-10

Family

ID=6053137

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19782846567 Pending DE2846567A1 (en) 1978-10-26 1978-10-26 NEW 1,4-CYCLOALKANOOXAZEPINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME
DE7979104083T Expired DE2966199D1 (en) 1978-10-26 1979-10-22 6,7-cycloalkano-1,4-oxazepines, process for their preparation and medicines containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19782846567 Pending DE2846567A1 (en) 1978-10-26 1978-10-26 NEW 1,4-CYCLOALKANOOXAZEPINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME

Country Status (23)

Country Link
US (1) US4336263A (en)
EP (2) EP0010717B1 (en)
JP (1) JPS6321670B2 (en)
AT (1) ATE4711T1 (en)
AU (1) AU531189B2 (en)
CA (1) CA1113090A (en)
CS (1) CS208458B2 (en)
DD (1) DD145915A5 (en)
DE (2) DE2846567A1 (en)
DK (1) DK150854C (en)
ES (1) ES485350A1 (en)
FI (1) FI66365C (en)
GR (1) GR65676B (en)
HU (1) HU177947B (en)
IE (1) IE49089B1 (en)
IL (1) IL58502A (en)
NO (1) NO149135C (en)
PL (1) PL115744B2 (en)
PT (1) PT70348A (en)
SU (1) SU799663A3 (en)
WO (1) WO1980000838A1 (en)
YU (1) YU261379A (en)
ZA (1) ZA795716B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52502B1 (en) * 1981-03-27 1987-11-25 Wyeth John & Brother Ltd Morpholines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3830803A (en) 1965-05-10 1974-08-20 Riker Laboratories Inc 5-loweralkyl-1-phenyl-1,3,4,6-tetrahydro-5h-benz(f)-2,5-oxazocines and 4-ones
US3598808A (en) * 1968-09-03 1971-08-10 Upjohn Co Perhydro-5-phenyl-cycloalkapolyene-1,4-oxazepines and their preparations
AT336026B (en) 1975-03-12 1977-04-12 Broschek G Chem Prod Gebro A PROCESS FOR THE PRODUCTION OF NEW 1,4-OXACEPINES AND - DIACEPINES

Also Published As

Publication number Publication date
EP0010717A1 (en) 1980-05-14
JPS6321670B2 (en) 1988-05-09
PL219169A2 (en) 1980-08-11
JPS55500865A (en) 1980-10-30
FI66365B (en) 1984-06-29
NO793421L (en) 1980-04-29
ATE4711T1 (en) 1983-10-15
IE49089B1 (en) 1985-07-24
DK272080A (en) 1980-06-25
SU799663A3 (en) 1981-01-23
HU177947B (en) 1982-02-28
EP0010717B1 (en) 1983-09-21
IE792014L (en) 1980-04-26
CA1113090A (en) 1981-11-24
GR65676B (en) 1980-10-17
AU531189B2 (en) 1983-08-11
AU5214479A (en) 1980-05-01
YU261379A (en) 1983-10-31
IL58502A (en) 1982-12-31
CS208458B2 (en) 1981-09-15
IL58502A0 (en) 1980-01-31
PL115744B2 (en) 1981-04-30
ZA795716B (en) 1980-11-26
WO1980000838A1 (en) 1980-05-01
ES485350A1 (en) 1980-05-16
FI793231A (en) 1980-04-27
DD145915A5 (en) 1981-01-14
PT70348A (en) 1979-11-01
DK150854C (en) 1988-02-29
NO149135B (en) 1983-11-14
NO149135C (en) 1984-02-29
DK150854B (en) 1987-07-06
FI66365C (en) 1984-10-10
US4336263A (en) 1982-06-22
DE2846567A1 (en) 1980-05-08
EP0020515A1 (en) 1981-01-07

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Legal Events

Date Code Title Description
8330 Complete renunciation