DE2963717D1 - Carbapenem derivatives, a process for their preparation and pharmaceutical compositions containing them - Google Patents

Carbapenem derivatives, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE2963717D1
DE2963717D1 DE7979300711T DE2963717T DE2963717D1 DE 2963717 D1 DE2963717 D1 DE 2963717D1 DE 7979300711 T DE7979300711 T DE 7979300711T DE 2963717 T DE2963717 T DE 2963717T DE 2963717 D1 DE2963717 D1 DE 2963717D1
Authority
DE
Germany
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
carbapenem derivatives
carbapenem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979300711T
Other languages
English (en)
Inventor
David Francis Corbett
Alfred John Eglington
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE2963717D1 publication Critical patent/DE2963717D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE7979300711T 1978-05-06 1979-04-26 Carbapenem derivatives, a process for their preparation and pharmaceutical compositions containing them Expired DE2963717D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1810178 1978-05-06
GB2435878 1978-05-30

Publications (1)

Publication Number Publication Date
DE2963717D1 true DE2963717D1 (en) 1982-11-04

Family

ID=26253157

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979300711T Expired DE2963717D1 (en) 1978-05-06 1979-04-26 Carbapenem derivatives, a process for their preparation and pharmaceutical compositions containing them

Country Status (6)

Country Link
US (1) US4278686A (de)
EP (1) EP0005348B1 (de)
AU (1) AU4665079A (de)
DE (1) DE2963717D1 (de)
DK (1) DK186179A (de)
ES (1) ES480264A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU503489B2 (en) * 1975-10-13 1979-09-06 Beecham Group Limited Substituted aminodeoxy clavulanic acid
DE2862394D1 (en) * 1978-01-26 1984-05-03 Beecham Group Plc Derivatives of clavulanic acid, process for their preparation and compositions containing them
DE2963580D1 (en) * 1978-08-02 1982-10-21 Beecham Group Plc Beta-lactam antibacterial agents, a process for their preparation and pharmaceutical compositions containing them
EP0024832B1 (de) * 1979-08-10 1985-03-13 Beecham Group Plc Beta-Lactam-Antibiotika, ihre Herstellung, sie enthaltende pharmazeutische Zusammensetzung und ihre Herstellung
US4426389A (en) 1979-09-27 1984-01-17 Beecham Group Limited Derivatives of clavulanic acid, a process for their preparation and their use
US4343807A (en) * 1979-09-27 1982-08-10 Beecham Group Limited Derivatives of clavulanic acid, a process for their preparation and their use
DK456580A (da) * 1979-10-29 1981-06-04 Beecham Group Ltd Fremgangsmaade til fremstilling af bicycliske beta-lactamringholdige forbindelser
EP0048096A1 (de) * 1980-09-13 1982-03-24 Beecham Group Plc Antimikrobielle beta-Lactam-Mittel
US4562182A (en) * 1980-12-23 1985-12-31 Beecham Group P.L.C. Compounds containing beta-lactams
JPS57109786A (en) * 1980-12-26 1982-07-08 Takeda Chem Ind Ltd Antibiotic c-19393e5 and its preparation
US4497742A (en) * 1981-03-04 1985-02-05 Takeda Chemical Industries, Ltd. Isomerization of β-lactam compounds
US4698339A (en) * 1983-09-28 1987-10-06 Takeda Chemical Industries, Ltd. Carbapenems, their production and use
EP0137403A3 (de) * 1983-09-28 1987-04-15 Takeda Chemical Industries, Ltd. Carbapenem-Verbindungen, ihre Herstellung und Verwendung
US5348875A (en) * 1989-09-07 1994-09-20 Kabushikikaisha Kibun Shokuhin Production of alginase from Enterobacter cloacae M-1 (FERM BP-2577)
US5409917A (en) * 1991-03-05 1995-04-25 Marvin S. Towsend Topical treatment of acne with cephalosporins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH633554A5 (en) * 1975-11-21 1982-12-15 Merck & Co Inc Process for the preparation of novel thienamycin derivatives.
US4181733A (en) * 1975-11-21 1980-01-01 Merck & Co., Inc. Carboxyl derivatives of thienamycin
DK145504C (da) * 1976-04-28 1983-04-25 Merck & Co Inc Fremgangsmaade til fremstilling af det antibiotiske stof 890a2og/eller det antibiotiske stof 890a5 og farmaceutisk acceptable salte deraf
US4162323A (en) * 1977-04-18 1979-07-24 Merck & Co., Inc. Antibiotic N-acetyl-dehydro-thienamycin
DE2724560A1 (de) * 1977-05-31 1978-12-21 Merck & Co Inc O-derivate von thienamycin

Also Published As

Publication number Publication date
US4278686A (en) 1981-07-14
ES480264A1 (es) 1980-09-01
DK186179A (da) 1979-12-10
EP0005348B1 (de) 1982-09-22
AU4665079A (en) 1979-11-08
EP0005348A1 (de) 1979-11-14

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Free format text: JUNG, E., DIPL.-CHEM. DR.PHIL. SCHIRDEWAHN, J., DIPL.-PHYS. DR.RER.NAT., PAT.-ANW., 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee